5VID

Receptor binding domain of BoNT/B in complex with mini-protein binder Bot.0671.2

Summary for 5VID

DescriptorBotulinum neurotoxin type B, Bot.0671.2 (3 entities in total)
Functional Keywordsmini-protein binder, inhibitor, toxin
Biological sourceClostridium botulinum
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Cellular locationBotulinum neurotoxin B light chain: Secreted. Botulinum neurotoxin B heavy chain: Secreted P10844
Total number of polymer chains9
Total molecular weight293076.98
Authors
Jin, R.,Lam, K.,Yao, G. (deposition date: 2017-04-15, release date: 2017-09-20, Last modification date: 2017-10-18)
Primary citation
Chevalier, A.,Silva, D.A.,Rocklin, G.J.,Hicks, D.R.,Vergara, R.,Murapa, P.,Bernard, S.M.,Zhang, L.,Lam, K.H.,Yao, G.,Bahl, C.D.,Miyashita, S.I.,Goreshnik, I.,Fuller, J.T.,Koday, M.T.,Jenkins, C.M.,Colvin, T.,Carter, L.,Bohn, A.,Bryan, C.M.,Fernandez-Velasco, D.A.,Stewart, L.,Dong, M.,Huang, X.,Jin, R.,Wilson, I.A.,Fuller, D.H.,Baker, D.
Massively parallel de novo protein design for targeted therapeutics.
Nature, 550:74-79, 2017
PubMed: 28953867 (PDB entries with the same primary citation)
DOI: 10.1038/nature23912
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.234900.1%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution