5G53
| Structure of the adenosine A2A receptor bound to an engineered G protein | 分子名称: | ADENOSINE RECEPTOR A2A, ENGINEERED DOMAIN OF HUMAN G ALPHA S LONG ISOFORM, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Carpenter, B, Nehme, R, Warne, T, Leslie, A.G.W, Tate, C.G. | 登録日 | 2016-05-19 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of the Adenosine A2A Receptor Bound to an Engineered G Protein Nature, 536, 2016
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3V6O
| Leptin Receptor-antibody complex | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Carpenter, B, Hemsworth, G.R, Ross, R.J, Artymiuk, P.J. | 登録日 | 2011-12-20 | 公開日 | 2012-03-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody. Structure, 20, 2012
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3VG0
| Antibody Fab fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Monoclonal antibody 9F8 Fab fragment H chain, ... | 著者 | Carpenter, B, Hemsworth, G.R, Ross, R.J, Artymiuk, P.J. | 登録日 | 2012-01-10 | 公開日 | 2012-03-14 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody. Structure, 20, 2012
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6FUF
| Crystal structure of the rhodopsin-mini-Go complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(o) subunit alpha, RETINAL, ... | 著者 | Tsai, C.-J, Weinert, T, Muehle, J, Pamula, F, Nehme, R, Flock, T, Nogly, P, Edwards, P.C, Carpenter, B, Gruhl, T, Ma, P, Deupi, X, Standfuss, J, Tate, C.G, Schertler, G.F.X. | 登録日 | 2018-02-27 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.117 Å) | 主引用文献 | Crystal structure of rhodopsin in complex with a mini-Gosheds light on the principles of G protein selectivity. Sci Adv, 4, 2018
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6OKO
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3CH6
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3TG6
| Crystal Structure of Influenza A Virus nucleoprotein with Ligand | 分子名称: | Nucleocapsid protein, [4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone | 著者 | Pearce, B.C, Lewis, H.A, McDonnell, P.A, Steinbacher, S, Kiefersauer, R, Mortl, M, Maskos, K, Edavettal, S, Baldwin, E.T, Langley, D.R. | 登録日 | 2011-08-17 | 公開日 | 2012-08-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Biophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors To be Published
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6GDG
| Cryo-EM structure of the adenosine A2A receptor bound to a miniGs heterotrimer | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Garcia-Nafria, J, Lee, Y. | 登録日 | 2018-04-23 | 公開日 | 2018-05-16 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | 主引用文献 | Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein. Elife, 7, 2018
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3QCF
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3QCG
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3QCC
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3QCH
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3QCE
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3QCL
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3QCM
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3QCK
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3QCI
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3QCD
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3QCJ
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3QCB
| Human receptor protein tyrosine phosphatase gamma, domain 1, apo | 分子名称: | Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION | 著者 | Sheriff, S. | 登録日 | 2011-01-16 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
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3QCN
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