5G53

Structure of the adenosine A2A receptor bound to an engineered G protein

Summary for 5G53

• Entry DOI: 10.2210/pdb5g53/pdb
• Descriptor: ADENOSINE RECEPTOR A2A, ENGINEERED DOMAIN OF HUMAN G ALPHA S LONG ISOFORM, N-ETHYL-5'-CARBOXAMIDO ADENOSINE, ... (5 entities in total)
• Functional Keywords: signaling protein, g protein coupled receptor, adenosine receptor, seven-helix receptor, integral membrane protein, gpcr, engineered g protein, gpcr-g protein complex, mini-gs
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 124745.90

Authors

Carpenter, B.,Nehme, R.,Warne, T.,Leslie, A.G.W.,Tate, C.G. (deposition date: 2016-05-19, release date: 2016-08-03, Last modification date: 2024-01-10)

• Primary citation: Carpenter, B.,Nehme, R.,Warne, T.,Leslie, A.G.W.,Tate, C.G.; Structure of the Adenosine A2A Receptor Bound to an Engineered G Protein; Nature, 536:104-, 2016; PubMed: 27462812; DOI: 10.1038/NATURE18966

Experimental method

X-RAY DIFFRACTION (3.4 Å)