6AF5
| DJ-1 after backsoaking | 分子名称: | CHLORIDE ION, ISATIN, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AFG
| DJ-1 with compound 9 | 分子名称: | 1-methylindole-2,3-dione, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AFH
| DJ-1 with compound 10 | 分子名称: | 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AFA
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6AFE
| DJ-1 with compound 7 | 分子名称: | 7-(trifluoromethyl)-1~{H}-indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AF9
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6AFJ
| DJ-1 with compound 13 | 分子名称: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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6AFF
| DJ-1 with compound 8 | 分子名称: | CHLORIDE ION, Protein/nucleic acid deglycase DJ-1, methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate | 著者 | Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. | 登録日 | 2018-08-08 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
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5CIP
| Crystal Structure of Unbound 4E10 | 分子名称: | FAB 4E10 HEAVY CHAIN, FAB 4E10 LIGHT CHAIN | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | 登録日 | 2015-07-13 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10 J.Virol., 89, 2015
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5CIL
| Crystal Structure of non-neutralizing version of 4E10 (WDWD) with epitope bound | 分子名称: | ACETATE ION, CHLORIDE ION, FAB 4E10 HEAVY CHAIN, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | 登録日 | 2015-07-13 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10 J.Virol., 89, 2015
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5CIN
| Crystal Structure of non-neutralizing version of 4E10 (DeltaLoop) with epitope bound | 分子名称: | CHLORIDE ION, FAB 4E10 HEAVY CHAIN, FAB 4E10 LIGHT CHAIN, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L, Tsumoto, K. | 登録日 | 2015-07-13 | 公開日 | 2015-09-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10 J.Virol., 89, 2015
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5YD4
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5YQ5
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5YD5
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5YD3
| Crystal structure of the scFv antibody 4B08 with epitope peptide | 分子名称: | Epitope peptide, GLYCEROL, SULFATE ION, ... | 著者 | Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. | 登録日 | 2017-09-11 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody J. Biochem., 164, 2018
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5YC5
| Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, ... | 著者 | Caaveiro, J.M.M, Tamura, H, Tsumoto, K, Kiyoshi, M. | 登録日 | 2017-09-06 | 公開日 | 2018-03-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered Fc gamma Receptor IIIa-Immobilized Column. Sci Rep, 8, 2018
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5YY4
| Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide | 分子名称: | C-C chemokine receptor type 5, CHLORIDE ION, SULFATE ION, ... | 著者 | Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. | 登録日 | 2017-12-07 | 公開日 | 2018-07-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody Biochemistry, 57, 2018
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3QUG
| Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Gallium-porphyrin | 分子名称: | GLYCEROL, Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING GA, ... | 著者 | Moriwaki, Y, Caaveiro, J.M.M, Tsumoto, K. | 登録日 | 2011-02-24 | 公開日 | 2011-03-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus. Biochemistry, 50, 2011
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3QUH
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3VUA
| Apo IsdH-NEAT3 in space group P3121 at a resolution of 1.85 A | 分子名称: | ACETATE ION, GLYCEROL, Iron-regulated surface determinant protein H, ... | 著者 | Vu, N.T, Caaveiro, J.M.M, Moriwaki, Y, Tsumoto, K. | 登録日 | 2012-06-26 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin To be Published
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3VTM
| Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin | 分子名称: | GLYCEROL, Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING INDIUM | 著者 | Vu, N.T, Caaveiro, J.M.M, Moriwaki, Y, Tsumoto, K. | 登録日 | 2012-05-31 | 公開日 | 2013-05-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus Protein Sci., 22, 2013
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3VWI
| High resolution crystal structure of FraC in the monomeric form | 分子名称: | AMMONIUM ION, CHLORIDE ION, Fragaceatoxin C, ... | 著者 | Tanaka, K, Morante, K, Caaveiro, J.M.M, Gonzalez-Manas, J.M, Tsumoto, K. | 登録日 | 2012-08-23 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for self-assembly of a cytolytic pore lined by protein and lipid Nat Commun, 6, 2015
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5Y25
| EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062 | 分子名称: | (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor | 著者 | Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A. | 登録日 | 2017-07-24 | 公開日 | 2018-07-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | 主引用文献 | Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nat.Chem.Biol., 15, 2019
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4WD4
| Crystal structure of human HO1 H25R | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K. | 登録日 | 2014-09-06 | 公開日 | 2015-09-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis Biochemistry, 55, 2016
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5GHW
| Crystal structure of broad neutralizing antibody 10E8 with long epitope bound | 分子名称: | Endogenous retrovirus group K member 8 Env polyprotein, FAB 10E8 HEAVY CHAIN, FAB 10E8 LIGHT CHAIN, ... | 著者 | Caaveiro, J.M.M, Rujas, E, Morante, K, Nieva, J.L, Tsumoto, K. | 登録日 | 2016-06-21 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface Sci Rep, 6, 2016
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