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4FTV
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BU of 4ftv by Molmil
The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide
Descriptor: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2012-06-28
Release date:2013-07-03
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
To be Published
1N8Q
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BU of 1n8q by Molmil
LIPOXYGENASE IN COMPLEX WITH PROTOCATECHUIC ACID
Descriptor: 3,4-DIHYDROXYBENZOIC ACID, FE (II) ION, lipoxygenase-3
Authors:Borbulevych, O.Y, Jankun, J, Selman, S.H, Skrzypczak-Jankun, E.
Deposit date:2002-11-21
Release date:2003-06-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 A resolution.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
3MYJ
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BU of 3myj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) (R1Y) peptide variant.
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-05-10
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
1TVB
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BU of 1tvb by Molmil
Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
1TVH
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BU of 1tvh by Molmil
Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
3HPJ
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BU of 3hpj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-06-04
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3IXA
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BU of 3ixa by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tax peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-09-03
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H7B
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BU of 3h7b by Molmil
Human Class I MHC HLA-A2 in complex with the Tel1p peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-04-24
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9H
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BU of 3h9h by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-04-30
Release date:2010-01-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
3H9S
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BU of 3h9s by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide
Descriptor: A6 TCR alpha chain, Beta-2-microglobulin, GLYCEROL, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2009-04-30
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
2GTW
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BU of 2gtw by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A27L substitution
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-28
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.548 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GUO
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BU of 2guo by Molmil
Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-05-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GTZ
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BU of 2gtz by Molmil
Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-28
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GT9
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BU of 2gt9 by Molmil
Human Class I MHC HLA-A2 in complex with the decameric Melan-A/MART-1(26-35) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-27
Release date:2007-06-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
3PWJ
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BU of 3pwj by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWN
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BU of 3pwn by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWL
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BU of 3pwl by Molmil
Human Class I MHC HLA-A2 in complex with the HuD peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3PWP
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BU of 3pwp by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
3QDJ
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BU of 3qdj by Molmil
The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-18
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3QEQ
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BU of 3qeq by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide
Descriptor: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-20
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3QDM
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BU of 3qdm by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide
Descriptor: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-18
Release date:2011-07-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3QEU
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BU of 3qeu by Molmil
The crystal structure of TCR DMF5
Descriptor: DMF5 alpha chain, DMF5 beta chain, GLYCEROL, ...
Authors:Borbulevych, O.Y, Santhanagopolan, S.M, Baker, B.M.
Deposit date:2011-01-20
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3QDG
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BU of 3qdg by Molmil
The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-18
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3D3V
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BU of 3d3v by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(3,4-difluoroPhenylalanine)) peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
Deposit date:2008-05-12
Release date:2009-06-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner.
Biochem.J., 423, 2009
3D39
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BU of 3d39 by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5(4-fluoroPhenylalanine)) peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Clemens, J.R, Baker, B.M.
Deposit date:2008-05-09
Release date:2009-06-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
Biochem.J., 423, 2009

 

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