Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7MER
DownloadVisualize
BU of 7mer by Molmil
Structure of ALDH4A1 complexed with trans-4-Hydroxy-L-proline
Descriptor: 4-HYDROXYPROLINE, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ...
Authors:Bogner, A.N, Stiers, K.M, Tanner, J.J.
Deposit date:2021-04-07
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline.
Protein Sci., 30, 2021
7MES
DownloadVisualize
BU of 7mes by Molmil
Structure of ALDH4A1 complexed with trans-4-Hydroxy-D-proline
Descriptor: (4S)-4-hydroxy-D-proline, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ...
Authors:Bogner, A.N, Stiers, K.M, Tanner, J.J.
Deposit date:2021-04-07
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline.
Protein Sci., 30, 2021
7SQN
DownloadVisualize
BU of 7sqn by Molmil
Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with (2S)-oxetane-2-carboxylic acid
Descriptor: (2S)-oxetane-2-carboxylic acid, Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2021-11-05
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase.
Org.Biomol.Chem., 20, 2022
8DKQ
DownloadVisualize
BU of 8dkq by Molmil
Minimal PutA proline dehydrogenase domain (design #2) complexed with 2-(Furan-2-yl)acetic acid
Descriptor: (furan-2-yl)acetic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-07-05
Release date:2022-12-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure-based engineering of minimal proline dehydrogenase domains for inhibitor discovery.
Protein Eng.Des.Sel., 35, 2022
8DKP
DownloadVisualize
BU of 8dkp by Molmil
Minimal PutA proline dehydrogenase domain (design #2) complexed with S-(-)-tetrahydro-2-furoic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, TETRAHYDROFURAN-2-CARBOXYLIC ACID
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-07-05
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Structure-based engineering of minimal proline dehydrogenase domains for inhibitor discovery.
Protein Eng.Des.Sel., 35, 2022
8DKO
DownloadVisualize
BU of 8dko by Molmil
Minimal PutA proline dehydrogenase domain (design #1) complexed with S-(-)-tetrahydro-2-furoic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, TETRAHYDROFURAN-2-CARBOXYLIC ACID
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-07-05
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based engineering of minimal proline dehydrogenase domains for inhibitor discovery.
Protein Eng.Des.Sel., 35, 2022
7MWT
DownloadVisualize
BU of 7mwt by Molmil
Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with 1,1-Cyclobutanedicarboxylate
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2021-05-17
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase.
Org.Biomol.Chem., 20, 2022
7MWV
DownloadVisualize
BU of 7mwv by Molmil
Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with cyclopropanecarboxylic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2021-05-17
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase.
Org.Biomol.Chem., 20, 2022
7MWU
DownloadVisualize
BU of 7mwu by Molmil
Structure of the E. coli PutA proline dehydrogenase domain (residues 86-630) complexed with cyclobutanecarboxylic acid
Descriptor: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2021-05-17
Release date:2022-01-19
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure-affinity relationships of reversible proline analog inhibitors targeting proline dehydrogenase.
Org.Biomol.Chem., 20, 2022
7US3
DownloadVisualize
BU of 7us3 by Molmil
Structure of Putrescine N-hydroxylase Involved Complexed with NADP+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putrescine N-hydroxylase, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2022-04-22
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and Structural Characterization of a Flavin-Dependent Putrescine N -Hydroxylase from Acinetobacter baumannii.
Biochemistry, 61, 2022
6XP3
DownloadVisualize
BU of 6xp3 by Molmil
Structure of human PYCR1 complexed with cyclopentanecarboxylic acid
Descriptor: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION, ...
Authors:Tanner, J.J, Bogner, A.N.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
6X9B
DownloadVisualize
BU of 6x9b by Molmil
Structure of proline utilization A with cis-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: (4R)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X9C
DownloadVisualize
BU of 6x9c by Molmil
Structure of proline utilization A with L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6XOZ
DownloadVisualize
BU of 6xoz by Molmil
Structure of human PYCR1 complexed with L-tetrahydro-2-furoic acid
Descriptor: CHLORIDE ION, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
6XP0
DownloadVisualize
BU of 6xp0 by Molmil
Structure of human PYCR1 complexed with N-formyl L-proline
Descriptor: 1-formyl-L-proline, Pyrroline-5-carboxylate reductase 1, mitochondrial
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
6X9A
DownloadVisualize
BU of 6x9a by Molmil
Structure of proline utilization A with trans-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: (4S)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6XP1
DownloadVisualize
BU of 6xp1 by Molmil
Structure of human PYCR1 complexed with L-thiazolidine-2-carboxylate
Descriptor: (2S)-1,3-thiazolidine-2-carboxylic acid, Pyrroline-5-carboxylate reductase 1, mitochondrial, ...
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
6X9D
DownloadVisualize
BU of 6x9d by Molmil
Structure of proline utilization A with trans-4-hydroxy-L-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: 4-HYDROXYPROLINE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6X99
DownloadVisualize
BU of 6x99 by Molmil
Structure of proline utilization A with D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site
Descriptor: Bifunctional protein PutA, D-PROLINE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A.
Arch.Biochem.Biophys., 698, 2020
6XP2
DownloadVisualize
BU of 6xp2 by Molmil
Structure of human PYCR1 complexed with L-thiazolidine-4-carboxylate
Descriptor: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION, ...
Authors:Tanner, J.J, Christensen, E.M.
Deposit date:2020-07-07
Release date:2020-11-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1.
J.Biol.Chem., 295, 2020
7MYB
DownloadVisualize
BU of 7myb by Molmil
Structure of proline utilization A with tetrahydrothiophene-2-carboxylate bound in the proline dehydrogenase active site
Descriptor: (2R)-thiolane-2-carboxylic acid, (2S)-thiolane-2-carboxylic acid, Bifunctional protein PutA, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MY9
DownloadVisualize
BU of 7my9 by Molmil
Structure of proline utilization A with 1,3-dithiolane-2-carboxylate bound in the proline dehydrogenase active site
Descriptor: 1,3-dithiolane-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.628 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MYA
DownloadVisualize
BU of 7mya by Molmil
Structure of proline utilization A with the FAD covalently-modified by 1,3-dithiolane
Descriptor: Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021
7MYC
DownloadVisualize
BU of 7myc by Molmil
Structure of proline utilization A with the FAD covalently modified by tetrahydrothiophene
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanner, J.J, Campbell, A.C.
Deposit date:2021-05-20
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles.
Acs Chem.Biol., 16, 2021

221371

PDB entries from 2024-06-19

PDB statisticsPDBj update infoContact PDBjnumon