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5E6J
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BU of 5e6j by Molmil
Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe
Descriptor: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ...
Authors:Lima, C.D, Bekes, M.
Deposit date:2015-10-09
Release date:2016-05-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Mol. Cell, 62, 2016
2G1P
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BU of 2g1p by Molmil
Structure of E. coli DNA adenine methyltransferase (DAM)
Descriptor: 5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3', DNA adenine methylase, GLYCEROL, ...
Authors:Horton, J.R, Liebert, K, Bekes, M, Jeltsch, A, Cheng, X.
Deposit date:2006-02-14
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase.
J.Mol.Biol., 358, 2006
8SGE
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BU of 8sge by Molmil
KLHDC2 Kelch Domain with ligand KDRLKZ-1
Descriptor: GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid
Authors:Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K.
Deposit date:2023-04-12
Release date:2024-01-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.509 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8SGF
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BU of 8sgf by Molmil
KLHDC2 Kelch Domain with KLHDC2 c-terminal peptide bound
Descriptor: GLYCEROL, HIS-SER-VAL-ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2
Authors:Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K.
Deposit date:2023-04-12
Release date:2024-01-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.418 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8SH2
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BU of 8sh2 by Molmil
KLHDC2 in complex with EloB and EloC
Descriptor: Elongin-B, Elongin-C, Kelch domain-containing protein 2
Authors:Digianantonio, K.M, Bekes, M.
Deposit date:2023-04-13
Release date:2024-01-03
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
6WX4
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BU of 6wx4 by Molmil
Crystal structure of the SARS CoV-2 Papain-like protease in complex with peptide inhibitor VIR251
Descriptor: Non-structural protein 3, VIR251, ZINC ION
Authors:Lv, Z, Olsen, S.K.
Deposit date:2020-05-09
Release date:2020-05-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.655 Å)
Cite:Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.
Sci Adv, 6, 2020
6WUU
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BU of 6wuu by Molmil
Crystal structure of the SARS CoV-2 Papain-like protease in complex with peptide inhibitor VIR250
Descriptor: MAGNESIUM ION, Non-structural protein 3, VIR250, ...
Authors:Lv, Z, Olsen, S.K.
Deposit date:2020-05-05
Release date:2020-05-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.
Sci Adv, 6, 2020
7LFV
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BU of 7lfv by Molmil
Crystal structure of the SARS CoV-1 Papain-like protease in complex with peptide inhibitor VIR251
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
Authors:Olsen, S.K, Lv, Z.
Deposit date:2021-01-18
Release date:2021-11-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease.
Cell Rep, 36, 2021
7LFU
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BU of 7lfu by Molmil
Crystal structure of the SARS CoV-1 Papain-like protease in complex with peptide inhibitor VIR250
Descriptor: Papain-like protease peptide inhibitor VIR250, papain-like protease
Authors:Olsen, S.K, Lv, Z.
Deposit date:2021-01-18
Release date:2021-11-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease.
Cell Rep, 36, 2021
2ORE
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BU of 2ore by Molmil
Binary Structure of Escherichia coli DNA Adenine Methyltransferase and S-adenosylhomocysteine
Descriptor: DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION
Authors:Horton, J.R, Cheng, X.
Deposit date:2007-02-02
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Two Alternative Conformations of S-Adenosyl-L-homocysteine Bound to Escherichia coli DNA Adenine Methyltransferase and the Implication of Conformational Changes in Regulating the Catalytic Cycle.
J.Biol.Chem., 282, 2007

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