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2LSU
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BU of 2lsu by Molmil
The NMR high resolution structure of yeast Tah1 in a free form
Descriptor: TPR repeat-containing protein associated with Hsp90
Authors:Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X.
Deposit date:2012-05-07
Release date:2013-05-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex.
Structure, 21, 2013
2LSV
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BU of 2lsv by Molmil
The NMR high resolution structure of yeast Tah1 in complex with the Hsp90 C-terminal tail
Descriptor: ATP-dependent molecular chaperone HSP82, TPR repeat-containing protein associated with Hsp90
Authors:Back, R, Dominguez, C, Rothe, B, Bobo, C, Beaufils, C, Morera, S, Meyer, P, Charpentier, B, Branlant, C, Allain, F, Manival, X.
Deposit date:2012-05-07
Release date:2013-05-22
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex.
Structure, 21, 2013
5LM5
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BU of 5lm5 by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM2 peptide (region 435-451)
Descriptor: DNA topoisomerase 2-associated protein PAT1, mRNA decapping protein 2
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-29
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LMG
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BU of 5lmg by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM10 peptide (region 954-970)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-30
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LMF
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BU of 5lmf by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM3 peptide (region 484-500)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-30
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LON
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BU of 5lon by Molmil
Structure of /K. lactis/ Dcp1-Dcp2 decapping complex.
Descriptor: KLLA0E01827p, KLLA0F23980p
Authors:Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M.
Deposit date:2016-08-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
5LOP
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BU of 5lop by Molmil
Structure of the active form of /K. lactis/ Dcp1-Dcp2-Edc3 decapping complex bound to m7GDP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, KLLA0A11308p, KLLA0E01827p, ...
Authors:Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M.
Deposit date:2016-08-09
Release date:2016-10-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
4OGP
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BU of 4ogp by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator (Space group : P21)
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA topoisomerase 2-associated protein PAT1
Authors:Fourati-Kammoun, Z, Kolesnikova, O, Back, R, Keller, J, Lazar, N, Gaudon-Plesse, C, Seraphin, B, Graille, M.
Deposit date:2014-01-16
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.
Plos One, 9, 2014
4OJJ
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BU of 4ojj by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator (Space group : P212121)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Fourati-Kammoun, Z, Kolesnikova, O, Back, R, Keller, J, Lazar, N, Gaudon-Plesse, C, Seraphin, B, Graille, M.
Deposit date:2014-01-21
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.
Plos One, 9, 2014
2MJF
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BU of 2mjf by Molmil
Solution structure of the complex between the yeast Rsa1 and Hit1 proteins
Descriptor: Protein HIT1, Ribosome assembly 1 protein
Authors:Quinternet, M, Roth, B, Back, R, Jacquemin, C, Manival, X.
Deposit date:2014-01-08
Release date:2014-09-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction.
Nucleic Acids Res., 42, 2014
6Y3Z
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BU of 6y3z by Molmil
Crystal structure of the Pby1 ATP-grasp enzyme bound to the S. cerevisiae mRNA decapping complex (Dcp1-Dcp2-Edc3)
Descriptor: Enhancer of mRNA-decapping protein 3, MAGNESIUM ION, Probable tubulin--tyrosine ligase PBY1, ...
Authors:Graille, M.
Deposit date:2020-02-19
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
6Y3P
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BU of 6y3p by Molmil
Crystal structure of the C-terminal domain from K. lactis Pby1, an ATP-grasp enzyme interacting with the mRNA decapping enzyme Dcp2
Descriptor: KLLA0B12012p, SULFATE ION
Authors:Graille, M.
Deposit date:2020-02-18
Release date:2020-04-29
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
2MNJ
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BU of 2mnj by Molmil
NMR solution structure of the yeast Pih1 and Tah1 C-terminal domains complex
Descriptor: Protein interacting with Hsp90 1, TPR repeat-containing protein associated with Hsp90
Authors:Quinternet, M, Jacquemin, C, Charpentier, B, Manival, X.
Deposit date:2014-04-08
Release date:2015-08-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP Assembly.
J.Mol.Biol., 427, 2015
2M3F
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BU of 2m3f by Molmil
NMR structure of Rsa1p238-259 from S. Cerevisiae
Descriptor: Ribosome assembly 1 protein
Authors:Quinternet, M, Manival, X.
Deposit date:2013-01-17
Release date:2013-11-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly.
Nucleic Acids Res., 42, 2014
8C7M
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BU of 8c7m by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb fragment.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FAb4 Crystal Kappa Light chain, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-01-16
Release date:2024-01-31
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR6
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BU of 8cr6 by Molmil
mouse Interleukin-12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit alpha, Interleukin-12 subunit beta, ...
Authors:Merceron, R, Felix, J, Lambert, E, Bloch, Y, Savvides, S.N.
Deposit date:2023-03-07
Release date:2024-02-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR5
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BU of 8cr5 by Molmil
Murine Interleukin-12 receptor beta 1 domain 1 in complex with murine Interleukin-12 beta.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1, Interleukin-12 subunit beta, ...
Authors:Merceron, R, Bloch, Y, Felix, J, Savvides, S.N.
Deposit date:2023-03-07
Release date:2024-02-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8CR8
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BU of 8cr8 by Molmil
human Interleukin-23
Descriptor: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-03-08
Release date:2024-02-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8ODZ
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BU of 8odz by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ...
Authors:Felix, J, Bloch, Y, Savvides, S.N.
Deposit date:2023-03-10
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE4
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BU of 8oe4 by Molmil
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
Authors:Bloch, Y, Felix, J, Savvides, S.N.
Deposit date:2023-03-10
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8ODX
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BU of 8odx by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and VHH.
Descriptor: FAb4 Heavy chain, FAb4 Light chain, Interleukin-12 receptor subunit beta-1, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-03-09
Release date:2024-02-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE0
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BU of 8oe0 by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
Authors:Felix, J, Bloch, Y, Savvides, S.N.
Deposit date:2023-03-10
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8PB1
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BU of 8pb1 by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1), obtained after local refinement.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ...
Authors:Felix, J, Bloch, Y, Savvides, S.N.
Deposit date:2023-06-08
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8COO
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BU of 8coo by Molmil
Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3')
Authors:Nicastro, G, Abis, G, Taylor, I.A, Ramos, A.
Deposit date:2023-02-28
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023
8Q5B
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BU of 8q5b by Molmil
Characterization of the zinc finger u-protein HVO_0758 from Haloferax volcanii: biological roles, zinc binding, and NMR solution structure
Descriptor: Small CPxCG-related zinc finger protein
Authors:Pyper, D.J, Schwalbe, H.
Deposit date:2023-08-08
Release date:2023-12-27
Method:SOLUTION NMR
Cite:Characterization of the zinc finger mu-protein HVO_0758 from Haloferax volcanii : biological roles, zinc binding, and NMR solution structure.
Front Microbiol, 14, 2023

 

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