2QV8
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2RET
| The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus | 分子名称: | CHLORIDE ION, EpsJ, Pseudopilin EpsI, ... | 著者 | Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J. | 登録日 | 2007-09-27 | 公開日 | 2008-02-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus. J.Mol.Biol., 375, 2008
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7UP7
| Crystal structure of C-terminal Domain of MSK1 in complex with covalently bound with literature RSK2 inhibitor indazole cyanoacrylamide compound 26 (soak) | 分子名称: | (2S)-2-cyano-N-(1-hydroxy-2-methylpropan-2-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]propanamide, Ribosomal protein S6 kinase alpha-5 | 著者 | Yano, J.K, Abendroth, J, Hall, A. | 登録日 | 2022-04-14 | 公開日 | 2022-07-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. Acs Med.Chem.Lett., 13, 2022
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7UP8
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7UP4
| Crystal structure of C-terminal Domain of MSK1 in complex with covalently bound pyrrolopyrimidine compound 20 (co-crystal) | 分子名称: | (5M)-5-(2,5-dichloropyrimidin-4-yl)-5H-pyrrolo[3,2-d]pyrimidine, Ribosomal protein S6 kinase alpha-5 | 著者 | Yano, J.K, Abendroth, J, Hall, A. | 登録日 | 2022-04-14 | 公開日 | 2022-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. Acs Med.Chem.Lett., 13, 2022
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7UP6
| Crystal structure of C-terminal domain of MSK1 in complex with in covalently bound literature RSK2 inhibitor pyrrolopyrimidine cyanoacrylamide compound 25 (co-crystal) | 分子名称: | (E)-3-(3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)-2-cyanoacrylamide bound form, OXAMIC ACID, Ribosomal protein S6 kinase alpha-5 | 著者 | Yano, J.K, Abendroth, J, Hall, A. | 登録日 | 2022-04-14 | 公開日 | 2022-08-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. Acs Med.Chem.Lett., 13, 2022
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7RBX
| Crystal structure of isocitrate lyase and phosphorylmutase:isocitrate lyase from Brucella melitensis biovar Abortus 2308 bound to itaconic acid | 分子名称: | 1,2-ETHANEDIOL, 2-methylidenebutanedioic acid, Isocitrase, ... | 著者 | Seattle Structural Genomics Center for Infectious Disease, Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2021-07-06 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice. Plos Pathog., 17, 2021
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4XIN
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4XUX
| Structure of ampC bound to RPX-7009 at 1.75 A | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Beta-lactamase, ... | 著者 | Clifton, M.C, Abendroth, J. | 登録日 | 2015-01-26 | 公開日 | 2015-04-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of a Cyclic Boronic Acid beta-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases. J.Med.Chem., 58, 2015
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5DLC
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5E0I
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4OGX
| Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.4 Angstrom resolution | 分子名称: | DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, Plasma kallikrein, ... | 著者 | Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. | 登録日 | 2014-01-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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4OGY
| Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution | 分子名称: | 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ... | 著者 | Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. | 登録日 | 2014-01-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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6CHD
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6U94
| Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344 | 分子名称: | GLYCEROL, RND efflux system, outer membrane lipoprotein, ... | 著者 | Horanyi, P.S, Fox III, D, Abendroth, J, Lorimer, D, Edwards, T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2019-09-06 | 公開日 | 2019-10-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344 To Be Published
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6CAU
| UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UDP-N-acetylmuramate--L-alanine ligase | 著者 | Horanyi, P.S, Abendroth, J, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-01-31 | 公開日 | 2018-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | UDP-N-acetylmuramate--alanine ligase from Acinetobacter baumannii AB5075-UW with AMPPNP To be Published
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6CKG
| D-glycerate 3-kinase from Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487) | 分子名称: | 1,2-ETHANEDIOL, D-glycerate 3-kinase | 著者 | Horanyi, P.S, Abendroth, J, Lorimer, D.D, Edwards, T.E, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2018-02-28 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | D-glycerate 3-kinase from Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487) To be Published
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4NI5
| Crystal Structure of a Short Chain Dehydrogenase from Brucella suis | 分子名称: | MAGNESIUM ION, Oxidoreductase, short-chain dehydrogenase/reductase family protein | 著者 | Dranow, D.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2013-11-05 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of a Short Chain Dehydrogenase from Brucella suis TO BE PUBLISHED
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3UWB
| Crystal structure of a probable peptide deformylase from strucynechococcus phage S-SSM7 in complex with actinonin | 分子名称: | 1,2-ETHANEDIOL, ACTINONIN, CHLORIDE ION, ... | 著者 | Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F. | 登録日 | 2011-12-01 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure and function of a cyanophage-encoded peptide deformylase. ISME J, 7, 2013
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3UWA
| Crystal structure of a probable peptide deformylase from synechococcus phage S-SSM7 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, RIIA-RIIB membrane-associated protein, ZINC ION | 著者 | Lorimer, D, Abendroth, J, Edwards, T.E, Burgin, A, Segall, A, Rohwer, F. | 登録日 | 2011-12-01 | 公開日 | 2013-01-09 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure and function of a cyanophage-encoded peptide deformylase. ISME J, 7, 2013
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4KMS
| Crystal structure of Acetoacetyl-CoA reductase from Rickettsia felis | 分子名称: | Acetoacetyl-CoA reductase | 著者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID), Abendroth, J, Lukacs, C, Edwards, T.E, Lorimer, D. | 登録日 | 2013-05-08 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis. Acta Crystallogr.,Sect.F, 77, 2021
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4EYE
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4PN3
| Crystal structure of 3-hydroxyacyl-CoA-dehydrogenase from Brucella melitensis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyacyl-CoA dehydrogenase | 著者 | Lukacs, C.M, Abendroth, J, Edwards, T.E, Lorimer, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2014-05-22 | 公開日 | 2014-06-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of 3-hydroxyacyl-CoA-dehydrogenase from Brucella melitensis To Be Published
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4PBC
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4PFZ
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