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7Y3C
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BU of 7y3c by Molmil
Crystal structure of TRIM7 bound to RACO-1
分子名称: E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y3B
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BU of 7y3b by Molmil
Crystal structure of TRIM7 bound to GN1
分子名称: E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7Y3A
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BU of 7y3a by Molmil
Crystal structure of TRIM7 bound to 2C
分子名称: E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
分子名称: Optineurin, ubiquitin
著者Li, F, Pan, L.
登録日2016-11-23
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5X0W
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BU of 5x0w by Molmil
Molecular mechanism for the binding between Sharpin and HOIP
分子名称: E3 ubiquitin-protein ligase RNF31, Sharpin
著者Liu, J, Li, F, Cheng, X, Pan, L.
登録日2017-01-23
公開日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
5YDR
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BU of 5ydr by Molmil
Structure of DNMT1 RFTS domain in complex with ubiquitin
分子名称: DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ...
著者Qian, C.
登録日2017-09-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
Nucleic Acids Res., 46, 2018
7EAA
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BU of 7eaa by Molmil
crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain
分子名称: Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA7
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BU of 7ea7 by Molmil
crystal structure of NAP1 LIR in complex with GABARAP
分子名称: Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
7EA2
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BU of 7ea2 by Molmil
crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain
分子名称: 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
著者Fu, T, Pan, L.
登録日2021-03-06
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
8GTN
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BU of 8gtn by Molmil
Cryo-EM structure of the gasdermin B pore
分子名称: Isoform 4 of Gasdermin-B
著者Hou, Y.J, Cheng, H, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTK
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BU of 8gtk by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex
分子名称: GSDMB isoform-1, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTJ
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BU of 8gtj by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
分子名称: Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
5GIY
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BU of 5giy by Molmil
HSA-Palmitic acid-[RuCl5(ind)]2-
分子名称: PALMITIC ACID, Serum albumin, pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)
著者Yang, F, Wang, T.
登録日2016-06-25
公開日2017-07-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.543 Å)
主引用文献Structure of HSA-Palmitic acid-[RuCl5(ind)]2-
To Be Published
6JPE
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BU of 6jpe by Molmil
Crystal structure of FGFR4 kinase domain with irreversible inhibitor 1
分子名称: Fibroblast growth factor receptor 4, N-[2-[[6-[2-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]amino]pyridin-3-yl]pyrimidin-4-yl]amino]-3-methyl-phenyl]prop-2-enamide, SULFATE ION
著者Chen, X, Dai, S, Zhou, Z, Chen, Y.
登録日2019-03-26
公開日2020-05-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma.
J.Med.Chem., 63, 2020
7YFK
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BU of 7yfk by Molmil
The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin
分子名称: Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
著者Xia, Y, Yao, D, Huang, C, Cao, Y.
登録日2022-07-08
公開日2023-06-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Nat Commun, 14, 2023

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件を2024-05-15に公開中

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