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6LJM
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BU of 6ljm by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P13
分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-SER-LEU-GLY-SLL, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6LJN
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BU of 6ljn by Molmil
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P15
分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-HIS-PHE-SER-SLL, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
6LJK
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BU of 6ljk by Molmil
Crystal structure of human Sirt5 in complex with an internally quenched fluorescent substrate GluIQF
分子名称: BE2-SER-ALA-ILE-LYS-SER-NIY-GLY-SET, GLUTARIC ACID, NAD-dependent protein deacylase sirtuin-5, ...
著者Chen, Q, Yu, Y.
登録日2019-12-17
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.394 Å)
主引用文献Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.
Eur.J.Med.Chem., 192, 2020
7XF3
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BU of 7xf3 by Molmil
The structure of HLA-B*1501/BM58-66AF9
分子名称: 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen
著者Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L.
登録日2022-03-31
公開日2023-02-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape.
J Immunol., 210, 2023
8GUO
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BU of 8guo by Molmil
Crystal structure of the nuclease domain of EsaD in complex with EsaG from Staphylococcus aureus
分子名称: Type VII secretion system protein EsaG, Type VII secretion system protein EssD
著者Zhang, Z.M, Wang, Y.J.
登録日2022-09-13
公開日2022-11-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5939517 Å)
主引用文献A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
8GUP
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BU of 8gup by Molmil
Crystal structure of EsaG from Staphylococcus aureus
分子名称: CITRIC ACID, Type VII secretion system protein EsaG
著者Zhang, Z.M, Wang, Y.J.
登録日2022-09-13
公開日2022-11-09
実験手法X-RAY DIFFRACTION (2.298725 Å)
主引用文献A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
8GUN
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BU of 8gun by Molmil
Crystal structure of mutant H528A of EsaD from Staphylococcus aureus
分子名称: MAGNESIUM ION, Type VII secretion system protein EssD
著者Zhang, Z.M, Wang, Y.J.
登録日2022-09-13
公開日2022-11-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.30001378 Å)
主引用文献A toxin-deformation dependent inhibition mechanism in the T7SS toxin-antitoxin system of Gram-positive bacteria.
Nat Commun, 13, 2022
7FAQ
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Crystal structure of PDE5A in complex with inhibitor L1
分子名称: 2-[(4-chlorophenyl)methyl]-5-methoxy-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one, MAGNESIUM ION, SULFATE ION, ...
著者Wu, D, Huang, Y.Y, Luo, H.B.
登録日2021-07-07
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.200136 Å)
主引用文献Free energy perturbation (FEP)-guided scaffold hopping.
Acta Pharm Sin B, 12, 2022
7FAR
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BU of 7far by Molmil
Crystal structure of PDE5A in complex with inhibitor L12
分子名称: 5-[bis(fluoranyl)methoxy]-2-[(4-chlorophenyl)methyl]-10-(3-methoxypropyl)-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one, MAGNESIUM ION, ZINC ION, ...
著者Wu, D, Huang, Y.Y, Luo, H.B.
登録日2021-07-07
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.40006471 Å)
主引用文献Free energy perturbation (FEP)-guided scaffold hopping.
Acta Pharm Sin B, 12, 2022
7Y73
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Crystal structure of sDscam Ig1 domain, isoform beta3v7
分子名称: Down Syndrome Cell Adhesion Molecules, GLYCEROL
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-21
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8I
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Crystal structure of sDscam FNIII3 domain, isoform alpha7
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ...
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y9A
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BU of 7y9a by Molmil
Crystal structure of sDscam Ig1-2 domains, isoform beta2v6
分子名称: Down Syndrome Cell Adhesion Molecules, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)][beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5J
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BU of 7y5j by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha1v7
分子名称: Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-17
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8S
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Crystal structure of sDscam FNIII1-3 domains, isoform beta2v6
分子名称: Dscam, SODIUM ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6O
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Crystal structure of sDscam Ig1-3 domains, isoform alpha25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-21
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y54
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BU of 7y54 by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha1
分子名称: Down Syndrome Cell Adhesion Molecules
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-16
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y5R
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BU of 7y5r by Molmil
Crystal structure of sDscam FNIII2 domain, isoform alpha7
分子名称: Down Syndrome Cell Adhesion Molecules, GLYCEROL
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-17
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.562 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y4X
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BU of 7y4x by Molmil
Crystal structure of sDscam Ig1 domain, isoform alpha7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-16
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.952 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y6E
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BU of 7y6e by Molmil
Crystal structure of sDscam FNIII23 domains, isoform Beta2v6
分子名称: Dscam
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-20
公開日2023-05-24
実験手法X-RAY DIFFRACTION (3.034 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y95
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Crystal structure of sDscam Ig1 domain, isoform beta6v2
分子名称: Dscam, GLYCEROL, SODIUM ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
7Y8H
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BU of 7y8h by Molmil
Crystal structure of sDscam FNIII1 domain, isoform alpha7
分子名称: Down Syndrome Cell Adhesion Molecules, SULFATE ION
著者Chen, Q, Yu, Y, Cheng, J.
登録日2022-06-23
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
8HN9
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BU of 8hn9 by Molmil
Human SIRT3 Recognizing CCNE2K348la peptide
分子名称: CCNE2 peptide, IMIDAZOLE, NAD-dependent protein deacetylase sirtuin-3, ...
著者Wang, Y, Ding, W.
登録日2022-12-07
公開日2023-05-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth.
Embo Rep., 24, 2023
7VS2
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secreted fungal effector protein MoErs1
分子名称: MoErs1
著者Wang, F.F, Xing, W.M.
登録日2021-10-25
公開日2023-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting Magnaporthe oryzae effector MoErs1 and host papain-like protease OsRD21 interaction to combat rice blast.
Nat.Plants, 2024
7X8C
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BU of 7x8c by Molmil
Crystal structure of a KTSC family protein from Euryarchaeon Methanolobus vulcani
分子名称: KTSC domain-containing protein, SODIUM ION
著者Zhang, Z.F, Zhu, K.L, Chen, Y.Y, Cao, P, Gong, Y.
登録日2022-03-12
公開日2022-08-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Biochemical and structural characterization of a KTSC family single-stranded DNA-binding protein from Euryarchaea.
Int.J.Biol.Macromol., 216, 2022
7YI4
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Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state
分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
著者Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
登録日2022-07-14
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023

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