4HAF
 
 | | Crystal structure of fc-fragment of human IgG2 antibody (primitive crystal form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2 chain C region | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Zhao, Y, Gilliland, G. | | 登録日 | 2012-09-26 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface.
Mol.Immunol., 56, 2013
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7DRT
 | | Human Wntless in complex with Wnt3a | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhong, Q, Zhao, Y, Ye, F, Xiao, Z, Huang, G, Zhang, Y, Lu, P, Xu, W, Zhou, Q, Ma, D. | | 登録日 | 2020-12-29 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-09-08 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Cryo-EM structure of human Wntless in complex with Wnt3a.
Nat Commun, 12, 2021
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8HYA
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4J1L
 | | Mutant Endotoxin TeNT | | 分子名称: | Tetanus toxin, ZINC ION | | 著者 | Guo, J, Pan, X, Zhao, Y, Chen, S. | | 登録日 | 2013-02-01 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Engineering Clostridia Neurotoxins with elevated catalytic activity
Toxicon, 74, 2013
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8HMB
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with benidipine (BEN) | | 分子名称: | (3R)-1-benzylpiperidin-3-yl methyl (2R,3R,4R,5R,6S)-2,6-dimethyl-4-(3-nitrophenyl)piperidine-3,5-dicarboxylate, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HMA
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-12-02 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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8HLP
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Wei, Y, Yu, Z, Zhao, Y. | | 登録日 | 2022-11-30 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
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4JYY
 | | Crystal structure of the azide and iron substituted Clostrium difficile SOD2 complex | | 分子名称: | AZIDE ION, FE (III) ION, Superoxide dismutase | | 著者 | Li, W, Ying, T.L, Wang, C.L, Zhao, Y, Wang, H.F, Tan, X.S. | | 登録日 | 2013-04-01 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Crystal structure of the azide and iron substituted Clostrium difficile SOD2 complex
To be Published
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4JZG
 | | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | | 著者 | Li, W, Wang, C.L, Zhao, Y, Wang, H.F, Tan, S.X. | | 登録日 | 2013-04-02 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.321 Å) | | 主引用文献 | Crystal structure of a single cambialistic SOD2 occupied by Manganese ion from Clostridium difficile
To be Published
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4JZ2
 | | Crystal structure of Co ion substituted SOD2 from Clostridium difficile | | 分子名称: | COBALT (II) ION, Superoxide dismutase | | 著者 | Li, W, Ying, T.L, Wang, C.L, Zhao, Y, Wang, H.F, Tan, X.S. | | 登録日 | 2013-04-02 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of Co ion substituted SOD2 from Clostridium difficile
To be Published
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6OCP
 | | Crystal structure of a human GABAB receptor peptide bound to KCTD16 T1 | | 分子名称: | BTB/POZ domain-containing protein KCTD16, Gamma-aminobutyric acid type B receptor subunit 2 | | 著者 | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | | 登録日 | 2019-03-25 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OCR
 | | Crystal structure of human KCTD16 T1 domain | | 分子名称: | BTB/POZ domain-containing protein KCTD16 | | 著者 | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | | 登録日 | 2019-03-25 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OCT
 | | Crystal structure of human KCTD16 T1 domain | | 分子名称: | BTB/POZ domain-containing protein KCTD16 | | 著者 | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | | 登録日 | 2019-03-25 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8J76
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8J77
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8J75
 | | Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, monomeric state | | 分子名称: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), High affinity choline transporter 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Gao, Y, Qiu, Y, Zhao, Y. | | 登録日 | 2023-04-27 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Transport mechanism of presynaptic high-affinity choline uptake by CHT1.
Nat.Struct.Mol.Biol., 31, 2024
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8J74
 | | Human high-affinity choline transporter CHT1 in the HC-3-bound outward-facing open conformation, dimeric state | | 分子名称: | (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), CHOLESTEROL HEMISUCCINATE, HEXADECANE, ... | | 著者 | Gao, Y, Qiu, Y, Zhao, Y. | | 登録日 | 2023-04-27 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Transport mechanism of presynaptic high-affinity choline uptake by CHT1.
Nat.Struct.Mol.Biol., 31, 2024
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5YR0
 | | Structure of Beclin1-UVRAG coiled coil domain complex | | 分子名称: | Beclin-1, UV radiation resistance associated protein | | 著者 | Pan, X, Zhao, Y, He, Y. | | 登録日 | 2017-11-08 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZMM
 | | Structure of the Type IV phosphorothioation-dependent restriction endonuclease ScoMcrA | | 分子名称: | SULFATE ION, Uncharacterized protein McrA, ZINC ION | | 著者 | Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X. | | 登録日 | 2018-04-04 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
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5ZMN
 | | Sulfur binding domain and SRA domain of ScoMcrA complexed with phosphorothioated DNA | | 分子名称: | DNA (5'-D(*CP*CP*CP*GP*(GS)P*CP*CP*GP*GP*G)-3'), SULFATE ION, Uncharacterized protein McrA | | 著者 | Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X. | | 登録日 | 2018-04-04 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
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5ZMO
 | | Sulfur binding domain of ScoMcrA complexed with phosphorothioated DNA | | 分子名称: | DNA (5'-D(P*CP*CP*GP*(GS)P*CP*CP*GP*G)-3'), PHOSPHATE ION, Uncharacterized protein McrA | | 著者 | Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X. | | 登録日 | 2018-04-04 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
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4PX7
 | | Crystal structure of lipid phosphatase E. coli PgpB | | 分子名称: | GLYCEROL, LAURYL DIMETHYLAMINE-N-OXIDE, Phosphatidylglycerophosphatase | | 著者 | Fan, J, Jiang, D, Zhao, Y, Zhang, X.C. | | 登録日 | 2014-03-22 | | 公開日 | 2014-05-28 | | 最終更新日 | 2022-08-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4R6M
 | | Crystal Structure of DNA Duplex Containing Two Consecutive Mercury-mediated Base Pairs | | 分子名称: | DNA (5'-D(P*CP*GP*CP*GP*TP*TP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*TP*CP*GP*CP*G)-3'), MERCURY (II) ION | | 著者 | Xu, C.Y, Yu, F, Wang, L.H, Zhao, Y, Lin, T, Fan, C.H, He, J.H. | | 登録日 | 2014-08-26 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.357 Å) | | 主引用文献 | Crystal Structure of DNA Duplex Containing Two Consecutive Mercury-mediated Base Pairs
To be Published
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7EMA
 | | Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I | | 分子名称: | Beta-2-microglobulin, Leucocyte antigen, TYR-SER-SER-ASP-VAL-THR-THR-LEU-VAL | | 著者 | Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J. | | 登録日 | 2021-04-13 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I.
J.Virol., 96, 2022
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7EMB
 | | Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I | | 分子名称: | ALA-ALA-ALA-ILE-GLU-GLU-GLU-ASP-ILE, Beta-2-microglobulin, Leucocyte antigen | | 著者 | Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J. | | 登録日 | 2021-04-13 | | 公開日 | 2021-12-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I.
J.Virol., 96, 2022
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