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7XME
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BU of 7xme by Molmil
Structure of Influenza A virus polymerase basic protein 2 (PB2) with an azazindole derivative
分子名称: (2~{S},3~{S})-3-[[5-dimethoxyphosphoryl-4-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, IODIDE ION, Polymerase basic protein 2
著者Zhang, Z.
登録日2022-04-25
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.521 Å)
主引用文献Discovery of a novel azaindole derivatives targeting the influenza PB2 cap binding region
To Be Published
3VAX
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BU of 3vax by Molmil
Crystal structure of DndA from streptomyces lividans
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative uncharacterized protein dndA
著者Zhang, Z, Chen, F, Lin, K, Wu, G.
登録日2011-12-30
公開日2013-01-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation
Plos One, 7, 2012
1TPB
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BU of 1tpb by Molmil
OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-02-03
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
Biochemistry, 34, 1995
1TPC
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BU of 1tpc by Molmil
OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-02-03
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
Biochemistry, 34, 1995
1AQC
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BU of 1aqc by Molmil
X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
分子名称: PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1997-12-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
5JO4
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BU of 5jo4 by Molmil
Antibody Fab Fragment Complex
分子名称: D80 Fab Heavy Chain, D80 Fab Light Chain, G6 Fab Heavy Chain, ...
著者Zhang, Z, Prachanronarong, K.P, Marasco, W.A, Schiffer, C.A.S.
登録日2016-05-01
公開日2017-11-08
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural Basis of an Influenza Hemagglutinin Stem-Directed Antibody Retaining the G6 Idiotype
To Be Published
5JQD
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BU of 5jqd by Molmil
Antibody Fab Fragment
分子名称: D80 Fab Fragment Heavy Chain, D80 Fab Fragment Light Chain
著者Zhang, Z, Prachanronarong, K, Gellatly, K, Marasco, W.A, Schiffer, C.A.
登録日2016-05-04
公開日2017-11-08
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.591 Å)
主引用文献Structural Basis of an Influenza Hemagglutinin Stem-Directed Antibody Retaining the G6 Idiotype
To Be Published
5LUN
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BU of 5lun by Molmil
Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - P1 ultra-high resolution crystal form in complex with iron, N-oxalylglycine and arginine
分子名称: 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, FE (III) ION, ...
著者McDonough, M.A, Zhang, Z, Schofield, C.J.
登録日2016-09-09
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5MOF
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BU of 5mof by Molmil
Ethylene Forming Enzyme from Pseudomonas syringae pv. phaseolicola - I222 crystal form in complex with manganese and 2-oxoglutarate
分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, CHLORIDE ION, ...
著者McDonough, M.A, Zhang, Z, Schofield, C.J.
登録日2016-12-14
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6K9H
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BU of 6k9h by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-phenyl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-15
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of new LXR beta agonists as glioblastoma inhibitors.
Eur.J.Med.Chem., 194, 2020
6K10
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BU of 6k10 by Molmil
Non substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.78962183 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
6K0Z
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BU of 6k0z by Molmil
Substrate bound state of Staphylococcus Aureus AldH
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GLYCEROL
著者Zhang, Z, Tao, X.
登録日2019-05-08
公開日2020-05-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4967258 Å)
主引用文献Structural Insight into the Substrate Gating Mechanism by Staphylococcus aureus Aldehyde Dehydrogenase
CCS Chemistry, 2, 2020
6K9G
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BU of 6k9g by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{R},3~{R})-2'-[3-[4-(hydroxymethyl)-3-methylsulfonyl-phenyl]phenyl]-2-oxidanylidene-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-15
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of new LXR beta agonists as glioblastoma inhibitors.
Eur.J.Med.Chem., 194, 2020
1TPV
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BU of 1tpv by Molmil
S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
1TPU
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BU of 1tpu by Molmil
S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
6YPC
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BU of 6ypc by Molmil
Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
分子名称: Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ...
著者Bellini, D, Zhang, Z, Barford, D.
登録日2020-04-15
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex.
Nucleic Acids Res., 48, 2020
1X11
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BU of 1x11 by Molmil
X11 PTB DOMAIN
分子名称: 13-MER PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1998-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
4XPU
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BU of 4xpu by Molmil
The crystal structure of EndoV from E.coli
分子名称: Endonuclease V
著者Xie, W, Zhang, Z.
登録日2015-01-18
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of E. coli endonuclease V, an essential enzyme for deamination repair
Sci Rep, 5, 2015
7RY3
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BU of 7ry3 by Molmil
Multidrug Efflux pump AdeJ with TP-6076 bound
分子名称: (4S,4aS,5aR,12aS)-4-(diethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-8-[(2S)-pyrrolidin-2-yl]-7-(trifluoromethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, Efflux pump membrane transporter
著者Zhang, Z.
登録日2021-08-24
公開日2022-02-02
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii.
Mbio, 13, 2022
4NSP
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BU of 4nsp by Molmil
Crystal structure of human ENDOV
分子名称: Endonuclease V
著者Xie, W, Zhang, Z, Hao, Z.
登録日2013-11-28
公開日2014-09-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human endonuclease V as an inosine-specific ribonuclease.
Acta Crystallogr.,Sect.D, 70, 2014
8EOJ
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BU of 8eoj by Molmil
Microsomal triglyceride transfer protein
分子名称: Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase
著者Zhang, Z.
登録日2022-10-03
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EOR
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BU of 8eor by Molmil
Liver carboxylesterase 1
分子名称: ETHYL ACETATE, Liver carboxylesterase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zhang, Z, Yu, E.
登録日2022-10-04
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8ENE
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BU of 8ene by Molmil
Aldehyde dehydrogenase 1 family member A1 from human liver
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 1
著者Zhang, Z.
登録日2022-09-29
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
2NCA
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BU of 2nca by Molmil
Structural Model for the N-terminal Domain of Human Cdc37
分子名称: Hsp90 co-chaperone Cdc37
著者Zhang, Z, Keramisanou, D, Gelis, I.
登録日2016-03-23
公開日2016-05-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Mechanism of Protein Kinase Recognition and Sorting by the Hsp90 Kinome-Specific Cochaperone Cdc37.
Mol.Cell, 62, 2016
6K9M
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BU of 6k9m by Molmil
Human LXR-beta in complex with an agonist
分子名称: Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate
著者Zhang, Z, Zhou, H.
登録日2019-06-16
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors.
Eur.J.Med.Chem., 206, 2020

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