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1AU6
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BU of 1au6 by Molmil
SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX, DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3')
著者Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Farrell, N, Wang, A.H.-J.
登録日1997-09-11
公開日1998-02-25
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA.
Nat.Struct.Biol., 2, 1995
1AU5
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BU of 1au5 by Molmil
SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: Cisplatin, DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3')
著者Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Wang, A.H.-J.
登録日1997-09-11
公開日1998-02-25
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
4WGL
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BU of 4wgl by Molmil
Crystal structure of a GroEL D83A/R197A double mutant
分子名称: 60 kDa chaperonin
著者Yang, D, Fei, X, LaRonde, N.A, Beckett, D, Lund, P.A, Lorimer, G.H.
登録日2014-09-19
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.13 Å)
主引用文献Crystal structure of a GroEL D83A/R197A double mutant
To Be Published
1KKH
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BU of 1kkh by Molmil
Crystal Structure of the Methanococcus jannaschii Mevalonate Kinase
分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate Kinase
著者Yang, D, Shipman, L.W, Roessner, C.A, Scott, A.I, Sacchettini, J.C.
登録日2001-12-08
公開日2002-03-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily.
J.Biol.Chem., 277, 2002
7MGW
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BU of 7mgw by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in NaCl in occluded conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
著者Yang, D, Gouaux, E.
登録日2021-04-13
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
3EAB
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BU of 3eab by Molmil
Crystal structure of Spastin MIT in complex with ESCRT III
分子名称: CHMP1b, Spastin
著者Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H.
登録日2008-08-25
公開日2008-11-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15, 2008
8DE3
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BU of 8de3 by Molmil
Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
分子名称: 15B8 Fab heavy chain variable domain, 15B8 Fab light chain variable domain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yang, D, Gouaux, E.
登録日2022-06-19
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Native serotonin transporter in complex with 15B8 Fab antibody in the presence of cocaine
To Be Published
8DE4
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Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine
分子名称: (2S)-N-methyl-1-phenylpropan-2-amine, 15B8 Fab heavy chain variable domain, 15B8 Fab light chain variable domain, ...
著者Yang, D, Gouaux, E.
登録日2022-06-19
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Native serotonin transporter in complex with 15B8 Fab in the presence of methamphetamine
To be published
4KUL
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BU of 4kul by Molmil
Crystal structure of N-terminal acetylated yeast Sir3 BAH domain V83P mutant
分子名称: Regulatory protein SIR3
著者Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
4KUI
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BU of 4kui by Molmil
Crystal structure of N-terminal acetylated yeast Sir3 BAH domain
分子名称: ACETIC ACID, ISOPROPYL ALCOHOL, Regulatory protein SIR3
著者Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
4KUD
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BU of 4kud by Molmil
Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle
分子名称: Histone H2A.2, Histone H2B.1, Histone H3, ...
著者Yang, D, Fang, Q, Wang, M, Ren, R, Wang, H, He, M, Sun, Y, Yang, N, Xu, R.M.
登録日2013-05-22
公開日2013-08-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Nat.Struct.Mol.Biol., 20, 2013
3MHV
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BU of 3mhv by Molmil
Crystal Structure of Vps4 and Vta1
分子名称: Vacuolar protein sorting-associated protein 4, Vacuolar protein sorting-associated protein VTA1
著者Yang, D, Hurley, J.H.
登録日2010-04-09
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural role of the Vps4-Vta1 interface in ESCRT-III recycling
Structure, 18, 2010
7LI9
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BU of 7li9 by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI7
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BU of 7li7 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in occluded conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, DECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI8
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BU of 7li8 by Molmil
apo serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in inward open conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, DODECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LI6
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apo SERT reconstituted in lipid nanodisc in KCl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
7LIA
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BU of 7lia by Molmil
5-HT bound serotonin transporter reconstituted in lipid nanodisc in presence of NaCl in outward facing conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLESTEROL, ...
著者Yang, D, Gouaux, E.
登録日2021-01-26
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Illumination of serotonin transporter mechanism and role of the allosteric site.
Sci Adv, 7, 2021
8WUA
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BU of 8wua by Molmil
cryo-EM structure of human TMEM63A
分子名称: CSC1-like protein 1
著者Yang, D.
登録日2023-10-20
公開日2024-01-24
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A monomeric structure of human TMEM63A protein.
Proteins, 2024
2LUU
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BU of 2luu by Molmil
NMR solution structure of midkine-b, mdkb
分子名称: Midkine-related growth factor Mdk2
著者Yang, D, Lim, J, Meng, D.
登録日2012-06-21
公開日2013-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.
Biochem.J., 451, 2013
7O1F
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BU of 7o1f by Molmil
PCNA from Chaetomium thermophilum in complex with PolD4 PIP peptide
分子名称: Peptide fragment from PolD4, Proliferating cell nuclear antigen, SODIUM ION
著者Alphey, M.A, MacNeill, S, Yang, D.
登録日2021-03-29
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
7O1E
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BU of 7o1e by Molmil
Crystal structure of PCNA from Chaetomium thermophilum
分子名称: Proliferating cell nuclear antigen
著者Alphey, M.A, MacNeill, S, Yang, D.
登録日2021-03-29
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
2MQA
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BU of 2mqa by Molmil
3D structure of RP domain of MiSp
分子名称: Minor ampullate fibroin 1
著者Yang, D, Gao, Z.
登録日2014-06-16
公開日2015-06-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献3D structure of RP domain of MiSp
To be Published
2M0M
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BU of 2m0m by Molmil
Structural Characterization of Minor Ampullate Spidroin Domains and their Distinct Roles in Fibroin Solubility and Fiber Formation
分子名称: Minor ampullate fibroin 1
著者Yang, D, Gao, Z, Lin, Z, Huang, W, Lai, C, Fan, J.
登録日2012-10-30
公開日2013-03-27
実験手法SOLUTION NMR
主引用文献Structural characterization of minor ampullate spidroin domains and their distinct roles in fibroin solubility and fiber formation
Plos One, 8, 2013
6DZZ
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BU of 6dzz by Molmil
Cryo-EM Structure of the wild-type human serotonin transporter in complex with ibogaine and 15B8 Fab in the inward conformation
分子名称: (5beta)-12-methoxyibogamine, 15B8 antibody heavy chain, 15B8 antibody light chain, ...
著者Yang, D, Coleman, J.A, Gouaux, E.
登録日2018-07-05
公開日2019-04-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Nature, 569, 2019
7LWD
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Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide, ...
著者Yang, D, Kalenderoglou, I.E, Gouaux, E, Coleman, J.A, Loland, C.J.
登録日2021-03-01
公開日2021-08-11
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.
Nat Commun, 12, 2021

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