4A4T
 
 | | UNAC Tetraloops: To What Extent Can They Mimic GNRA Tetraloops | | Descriptor: | 5'-R(*GP*GP*AP*CP*CP*CP*GP*GP*CP*UP*UP*AP*CP*GP *CP*UP*GP*GP*GP*UP*CP*C)-3' | | Authors: | Zhao, Q, Huang, H, Nagaswamy, U, Xia, Y, Gao, X, Fox, G. | | Deposit date: | 2011-10-20 | | Release date: | 2012-05-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Unac Tetraloops: To What Extent Can They Mimic Gnra Tetraloops
Biopolymers, 97, 2012
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2HEM
 | | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit. | | Descriptor: | 5'-R(P*GP*GP*GP*AP*AP*GP*GP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*CP*GP*GP*CP*CP*C)-3' | | Authors: | Zhao, Q, Nagaswamy, U, Lee, H, Xia, Y, Gao, X, Fox, G. | | Deposit date: | 2006-06-21 | | Release date: | 2006-09-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure and Mg2+ binding of an RNA segment that underlies the L7/L12 stalk in the E.coli 50S ribosomal subunit
Nucleic Acids Res., 33, 2005
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4OR2
 | | Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, CHOLESTEROL, ... | | Authors: | Wu, H, Wang, C, Gregory, K.J, Han, G.W, Cho, H.P, Xia, Y, Niswender, C.M, Katritch, V, Cherezov, V, Conn, P.J, Stevens, R.C, GPCR Network (GPCR) | | Deposit date: | 2014-02-10 | | Release date: | 2014-03-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
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4I0U
 | | Improved structure of Thermotoga maritima CorA at 2.7 A resolution | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Nordin, N, Guskov, A, Phua, T, Sahaf, N, Xia, Y, Lu, S.Y, Eshaghi, H, Eshaghi, S. | | Deposit date: | 2012-11-19 | | Release date: | 2013-03-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport.
Biochem.J., 451, 2013
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6JMT
 | | Crystal structure of GIT/PIX complex | | Descriptor: | ARF GTPase-activating protein GIT2, ZINC ION, beta PIX | | Authors: | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | | Deposit date: | 2019-03-13 | | Release date: | 2020-05-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
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6JMU
 | | Crystal structure of GIT1/Paxillin complex | | Descriptor: | ARF GTPase-activating protein GIT1, Paxillin | | Authors: | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | | Deposit date: | 2019-03-13 | | Release date: | 2020-05-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
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2MZ0
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8JFQ
 | | Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-back Loop | | Descriptor: | 26mer-DNA | | Authors: | Liu, Y, Li, J, Zhang, Y, Wang, Y, Chen, J, Bian, Y, Xia, Y, Yang, M.H, Zheng, K, Wang, K.B, Kong, L.Y. | | Deposit date: | 2023-05-18 | | Release date: | 2023-08-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure of the Major G-Quadruplex in the Human EGFR Oncogene Promoter Adopts a Unique Folding Topology with a Distinctive Snap-Back Loop.
J.Am.Chem.Soc., 145, 2023
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8GV8
 | | The cryo-EM structure of hAE2 with DIDS | | Descriptor: | 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2 | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-14 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GVF
 | | The outward-facing structure of hAE2 in basic pH | | Descriptor: | Anion exchange protein 2 | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-15 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GVA
 | | The intermediate structure of hAE2 in basic pH | | Descriptor: | Anion exchange protein 2 | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-14 | | Release date: | 2023-04-12 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GVC
 | | The cryo-EM structure of hAE2 with bicarbonate | | Descriptor: | Anion exchange protein 2, BICARBONATE ION | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-14 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GV9
 | | The cryo-EM structure of hAE2 with chloride ion | | Descriptor: | Anion exchange protein 2, CHLORIDE ION | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-14 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GVE
 | | The asymmetry structure of hAE2 | | Descriptor: | Anion exchange protein 2 | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-15 | | Release date: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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8GVH
 | | Human AE2 in acidic KNO3 | | Descriptor: | Anion exchange protein 2, CHOLESTEROL HEMISUCCINATE | | Authors: | Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2022-09-15 | | Release date: | 2023-04-12 | | Last modified: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
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7CZB
 | | The cryo-EM structure of the ERAD retrotranslocation channel formed by human Derlin-1 | | Descriptor: | Derlin-1 | | Authors: | Rao, B, Li, S, Yao, D, Wang, Q, Xia, Y, Jia, Y, Shen, Y, Cao, Y. | | Deposit date: | 2020-09-07 | | Release date: | 2021-03-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The cryo-EM structure of an ERAD protein channel formed by tetrameric human Derlin-1.
Sci Adv, 7, 2021
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7EQ4
 | | Crystal Structure of the N-terminus of Nonstructural protein 1 from SARS-CoV-2 | | Descriptor: | Host translation inhibitor nsp1 | | Authors: | Liu, Y, Ke, Z, Hu, H, Zhao, K, Xiao, J, Xia, Y, Li, Y. | | Deposit date: | 2021-04-29 | | Release date: | 2021-06-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1.
Microbiol Spectr, 9, 2021
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7EWT
 | | The crystal structure of Lysophospholipid acyltransferase LPCAT3 (MOBAT5) in its monomeric and apo form | | Descriptor: | Lysophospholipid acyltransferase 5 | | Authors: | Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Cao, Y. | | Deposit date: | 2021-05-26 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
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7F3X
 | | Lysophospholipid acyltransferase LPCAT3 in complex with lysophosphatidylcholine | | Descriptor: | LPCAT3, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM | | Authors: | Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y. | | Deposit date: | 2021-06-17 | | Release date: | 2021-12-01 | | Last modified: | 2022-02-23 | | Method: | ELECTRON MICROSCOPY (3.57 Å) | | Cite: | The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
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7F40
 | | Lysophospholipid acyltransferase LPCAT3 in a complex with Arachidonoyl-CoA | | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, LPCAT3, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate | | Authors: | Zhang, Q, Yao, D, Rao, B, Li, S, Jian, L, Chen, Y, Hu, K, Xia, Y, Shen, Y, Cao, Y. | | Deposit date: | 2021-06-17 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-15 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3.
Nat Commun, 12, 2021
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7YIW
 | | The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Acidic pH | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ... | | Authors: | Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Cao, Y. | | Deposit date: | 2022-07-18 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
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7YIV
 | | The Crystal Structure of Human Tissue Nonspecific Alkaline Phosphatase (ALPL) at Basic pH | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ... | | Authors: | Cao, Y, Qin, A, Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y. | | Deposit date: | 2022-07-18 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
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7YIX
 | | The Cryo-EM Structure of Human Tissue Nonspecific Alkaline Phosphatase and Single-Chain Fragment Variable (ScFv) Complex. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, ... | | Authors: | Yu, Y.T, Yao, D.Q, Zhang, Q, Rao, B, Xia, Y, Lu, Y, Qin, A, Ma, P.X, Cao, Y. | | Deposit date: | 2022-07-18 | | Release date: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase.
Nat Commun, 14, 2023
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7Y53
 | | The cryo-EM structure of human ERAD retro-translocation complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase | | Authors: | Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y. | | Deposit date: | 2022-06-16 | | Release date: | 2023-10-18 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.61 Å) | | Cite: | The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
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7Y4W
 | | The cryo-EM structure of human ERAD retro-translocation complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase | | Authors: | Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y. | | Deposit date: | 2022-06-16 | | Release date: | 2023-10-18 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
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