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8VYG
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BU of 8vyg by Molmil
SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Heavy Chain, S309 Light Chain, ...
Authors:McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-08
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
8VYE
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BU of 8vye by Molmil
SARS-CoV-2 S (C.37 Lambda variant) plus S309, S2L20, and S2X303 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, S2L20 Light Chain, ...
Authors:McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-08
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
8VYF
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BU of 8vyf by Molmil
SARS-CoV-2 S NTD (C.37 Lambda variant) plus S2L20 and S2X303 Fabs, local refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, ...
Authors:McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-08
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.
Nat Commun, 15, 2024
8UR7
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BU of 8ur7 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-10-25
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
8UR5
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BU of 8ur5 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-1heptad-I53_dn5 (local refinement of TH-1heptad)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-10-25
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023
6WPT
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BU of 6wpt by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment (open state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WPS
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BU of 6wps by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S309 neutralizing antibody heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, De Marco, A, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
6WS6
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BU of 6ws6 by Molmil
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
Descriptor: O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), S309 antigen-binding (Fab) fragment, heavy chain, ...
Authors:Pinto, D, Park, Y.J, Beltramello, M, Walls, A.C, Tortorici, M.A, Bianchi, S, Jaconi, S, Culap, K, Zatta, F, Marco, A.D, Peter, A, Guarino, B, Spreafico, R, Cameroni, E, Case, J.B, Chen, R.E, Havenar-Daughton, C, Snell, G, Telenti, A, Virgin, H.W, Lanzavecchia, A, Diamond, M.S, Fink, K, Veesler, D, Corti, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-30
Release date:2020-05-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
Nature, 583, 2020
8U29
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BU of 8u29 by Molmil
Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ...
Authors:Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-09-05
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
8U0T
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BU of 8u0t by Molmil
PRD-0038 RBD bound to Rhinolophus alcyone ACE2 (local refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, PRD-0038, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-08-29
Release date:2023-12-06
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
6X79
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BU of 6x79 by Molmil
Prefusion SARS-CoV-2 S ectodomain trimer covalently stabilized in the closed conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:McCallum, M, Walls, A.C, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-05-29
Release date:2020-08-19
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation.
Nat.Struct.Mol.Biol., 27, 2020
6OHW
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BU of 6ohw by Molmil
Structural basis for human coronavirus attachment to sialic acid receptors. Apo-HCoV-OC43 S
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike surface glycoprotein, ...
Authors:Tortorici, M.A, Walls, A.C, Lang, Y, Wang, C, Li, Z, Koerhuis, D, Boons, G.J, Bosch, B.J, Rey, F.A, de Groot, R, Veesler, D.
Deposit date:2019-04-07
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
3JCL
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BU of 3jcl by Molmil
Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer
Descriptor: Spike glycoprotein
Authors:Walls, A.C, Tortorici, M.A, Bosch, B.J, Frenz, B, Rottier, P.J.M, DiMaio, F, Rey, F.A, Veesler, D.
Deposit date:2015-12-21
Release date:2016-02-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer.
Nature, 531, 2016
4IOS
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BU of 4ios by Molmil
Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11.
Descriptor: BPP, GLYCEROL, Llama nanobody 11
Authors:Desmyter, A, Farenc, C, Mahony, J, Spinelli, S, Bebeacua, C, Blangy, S, Veesler, D, van Sinderen, D, Cambillau, C.
Deposit date:2013-01-08
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
7SKZ
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BU of 7skz by Molmil
Crystal Structure of VN01H1 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain of VN01H1 Fab, Light chain of VN01H1 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-10-22
Release date:2022-07-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
7SL5
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BU of 7sl5 by Molmil
Crystal Structure of VP12E7 Fab in complex with SARS-CoV-2 S fusion peptide
Descriptor: Heavy chain VP12E7 Fab, Light chain VP12E7 Fab, PRO-SER-LYS-ARG-SER-PHE-ILE-GLU-ASP-LEU-LEU-PHE-ASN
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-10-22
Release date:2022-07-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.
Science, 377, 2022
6NB4
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BU of 6nb4 by Molmil
MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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BU of 6nb7 by Molmil
SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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BU of 6nb6 by Molmil
SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB3
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BU of 6nb3 by Molmil
MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LCA60 heavy chain, ...
Authors:Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
8VGT
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BU of 8vgt by Molmil
Structure of the HKU1 RBD bound to the human TMPRSS2 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-12-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human coronavirus HKU1 recognition of the TMPRSS2 host receptor
To Be Published
8TVB
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BU of 8tvb by Molmil
Ghanaian virus fusion glycoprotein (GhV F)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-08-17
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVI
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BU of 8tvi by Molmil
Langya Virus G glycoprotein (LayV G) with stabilizing mutations
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment glycoprotein G, ZINC ION
Authors:McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-08-18
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVE
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BU of 8tve by Molmil
Langya henipavirus fusion protein in postfusion state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya henipavirus fusion protein in postfusion state
Authors:Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-08-18
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TVH
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BU of 8tvh by Molmil
Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ...
Authors:Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-08-18
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024

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數據於2024-05-29公開中

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