8VYG

SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement

Summary for 8VYG

• Entry DOI: 10.2210/pdb8vyg/pdb
• Related: 8VYE 8VYF
• EMDB information: 43660
• Descriptor: S309 Heavy Chain, S309 Light Chain, Spike glycoprotein, ... (4 entities in total)
• Functional Keywords: sars-cov-2, coronavirus, lambda, s309, c.37, antibody, fab, s protein, spike, fusion protein, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 166471.39

Authors

McCallum, M.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2024-02-08, release date: 2024-03-27)

• Primary citation: Magaret, C.A.,Li, L.,deCamp, A.C.,Rolland, M.,Juraska, M.,Williamson, B.D.,Ludwig, J.,Molitor, C.,Benkeser, D.,Luedtke, A.,Simpkins, B.,Heng, F.,Sun, Y.,Carpp, L.N.,Bai, H.,Dearlove, B.L.,Giorgi, E.E.,Jongeneelen, M.,Brandenburg, B.,McCallum, M.,Bowen, J.E.,Veesler, D.,Sadoff, J.,Gray, G.E.,Roels, S.,Vandebosch, A.,Stieh, D.J.,Le Gars, M.,Vingerhoets, J.,Grinsztejn, B.,Goepfert, P.A.,de Sousa, L.P.,Silva, M.S.T.,Casapia, M.,Losso, M.H.,Little, S.J.,Gaur, A.,Bekker, L.G.,Garrett, N.,Truyers, C.,Van Dromme, I.,Swann, E.,Marovich, M.A.,Follmann, D.,Neuzil, K.M.,Corey, L.,Greninger, A.L.,Roychoudhury, P.,Hyrien, O.,Gilbert, P.B.; Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features.; Nat Commun, 15:2175-2175, 2024; PubMed: 38467646; DOI: 10.1038/s41467-024-46536-w

Experimental method

ELECTRON MICROSCOPY (3.1 Å)