8VGT

Structure of the HKU1 RBD bound to the human TMPRSS2 receptor

Summary for 8VGT

Entry DOI	10.2210/pdb8vgt/pdb
EMDB information	43224
Descriptor	Spike protein S1, Transmembrane protease serine 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	spike glycoprotein, fusion protein, structural genomics, seattle structural genomics center for infectious disease, ssgcid, inhibitor, viral protein
Biological source	Human coronavirus HKU1 (isolate N1) More
Total number of polymer chains	2
Total formula weight	84641.81
Authors	Park, Y.J.,Seattle Structural Genomics Center for Infectious Disease (SSGCID),Veesler, D. (deposition date: 2023-12-27, release date: 2024-03-06, Last modification date: 2024-07-17)
Primary citation	McCallum, M.,Park, Y.J.,Stewart, C.,Sprouse, K.R.,Addetia, A.,Brown, J.,Tortorici, M.A.,Gibson, C.,Wong, E.,Ieven, M.,Telenti, A.,Veesler, D. Human coronavirus HKU1 recognition of the TMPRSS2 host receptor. Cell, 2024 Cited by PubMed: 38964328 DOI: 10.1016/j.cell.2024.06.006 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation