8VGT
Structure of the HKU1 RBD bound to the human TMPRSS2 receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike protein S1 | polymer | 338 | 37321.8 | 1 | UniProt (Q5MQD0) Pfam (PF09408) In PDB | Human coronavirus HKU1 (isolate N1) | |
2 | B | Transmembrane protease serine 2 | polymer | 416 | 46232.0 | 1 | UniProt (O15393) Pfam (PF15494) Pfam (PF00089) In PDB | Homo sapiens (human) | Serine protease 10 |
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A: 320 - 614 (UniProt: Q5MQD0)
B: 109 - 492 (UniProt: O15393)
PDB | External Database | Details |
---|---|---|
Met 288 | - | initiating methionine |
Gly 289 | - | expression tag |
Ile 290 | - | expression tag |
Leu 291 | - | expression tag |
Pro 292 | - | expression tag |
Ser 293 | - | expression tag |
Pro 294 | - | expression tag |
Gly 295 | - | expression tag |
Met 296 | - | expression tag |
Pro 297 | - | expression tag |
Ala 298 | - | expression tag |
Leu 299 | - | expression tag |
Leu 300 | - | expression tag |
Ser 301 | - | expression tag |
Leu 302 | - | expression tag |
Val 303 | - | expression tag |
Ser 304 | - | expression tag |
Leu 305 | - | expression tag |
Leu 306 | - | expression tag |
Ser 307 | - | expression tag |
Val 308 | - | expression tag |
Leu 309 | - | expression tag |
Leu 310 | - | expression tag |
Met 311 | - | expression tag |
Gly 312 | - | expression tag |
Cys 313 | - | expression tag |
Val 314 | - | expression tag |
Ala 315 | - | expression tag |
Glu 316 | - | expression tag |
Thr 317 | - | expression tag |
Gly 318 | - | expression tag |
Thr 319 | - | expression tag |
Gly 615 | - | expression tag |
Gly 616 | - | expression tag |
Ser 617 | - | expression tag |
His 618 | - | expression tag |
His 619 | - | expression tag |
His 620 | - | expression tag |
His 621 | - | expression tag |
His 622 | - | expression tag |
His 623 | - | expression tag |
His 624 | - | expression tag |
His 625 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 91 | - | initiating methionine |
Lys 92 | - | expression tag |
Trp 93 | - | expression tag |
Val 94 | - | expression tag |
Thr 95 | - | expression tag |
Phe 96 | - | expression tag |
Ile 97 | - | expression tag |
Ser 98 | - | expression tag |
Leu 99 | - | expression tag |
Leu 100 | - | expression tag |
Phe 101 | - | expression tag |
Leu 102 | - | expression tag |
Phe 103 | - | expression tag |
Ser 104 | - | expression tag |
Ser 105 | - | expression tag |
Ala 106 | - | expression tag |
Tyr 107 | - | expression tag |
Ser 108 | - | expression tag |
- | Ser 250 | deletion |
Asp 251 | Ser 251 | engineered mutation |
Asp 252 | Arg 252 | engineered mutation |
Asp 253 | Gln 253 | engineered mutation |
Asp 254 | Ser 254 | engineered mutation |
Lys 255 | Arg 255 | engineered mutation |
Ala 441 | Ser 441 | engineered mutation |
Cys 447 | Thr 447 | engineered mutation |
Asp 493 | - | expression tag |
Asp 494 | - | expression tag |
Asp 495 | - | expression tag |
Asp 496 | - | expression tag |
Lys 497 | - | expression tag |
Ser 498 | - | expression tag |
Gly 499 | - | expression tag |
His 500 | - | expression tag |
His 501 | - | expression tag |
His 502 | - | expression tag |
His 503 | - | expression tag |
His 504 | - | expression tag |
His 505 | - | expression tag |
His 506 | - | expression tag |
His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 83553.8 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 663.6 | |
All* | Total formula weight | 84641.8 |