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5YD4
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BU of 5yd4 by Molmil
Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation T6A)
Descriptor: Epitope peptide (mutation T6A), SULFATE ION, scFv 4B08
Authors:Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K.
Deposit date:2017-09-11
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody
J. Biochem., 164, 2018
5YD5
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BU of 5yd5 by Molmil
Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation N3A)
Descriptor: Peptide epitope (mutation N3A), SULFATE ION, scFv 4B08
Authors:Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K.
Deposit date:2017-09-11
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody
J. Biochem., 164, 2018
1UFU
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BU of 1ufu by Molmil
Crystal structure of ligand binding domain of immunoglobulin-like transcript 2 (ILT2; LIR-1)
Descriptor: Immunoglobulin-like transcript 2
Authors:Shiroishi, M, Amano, K, Rasubala, L, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K.
Deposit date:2003-06-10
Release date:2004-08-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Kinetic and thermodynamic properties of the interaction between Immunoglobulin like transcript (ILT) and MHC class I
To be Published
7CMF
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BU of 7cmf by Molmil
Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
Descriptor: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3
Authors:Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K.
Deposit date:2020-07-27
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
7CME
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BU of 7cme by Molmil
Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
Descriptor: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ...
Authors:Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K.
Deposit date:2020-07-27
Release date:2021-09-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
1J1P
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BU of 1j1p by Molmil
Crystal structure of HyHEL-10 Fv mutant LS91A complexed with hen egg white lysozyme
Descriptor: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
Authors:Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I.
Deposit date:2002-12-13
Release date:2003-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION
J.BIOL.CHEM., 278, 2003
1J08
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BU of 1j08 by Molmil
Crystal structure of glutaredoxin-like protein from Pyrococcus horikoshii
Descriptor: glutaredoxin-like protein
Authors:Tanaka, Y, Tanabe, E, Tsumoto, K, Kumagai, I, Yao, M, Tanaka, I.
Deposit date:2002-11-11
Release date:2003-05-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Protein disulfide isomerase from hyperthermophile as an additives of refolding of an immunoglobulin-folded protein
To be Published
1J05
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BU of 1j05 by Molmil
The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
Descriptor: GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ...
Authors:Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I.
Deposit date:2002-11-01
Release date:2003-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
To be Published
1J1O
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BU of 1j1o by Molmil
Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme
Descriptor: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
Authors:Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I.
Deposit date:2002-12-13
Release date:2003-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION
J.BIOL.CHEM., 278, 2003
1J1X
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BU of 1j1x by Molmil
Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme
Descriptor: Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region
Authors:Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I.
Deposit date:2002-12-20
Release date:2003-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION
J.BIOL.CHEM., 278, 2003
1J2V
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BU of 1j2v by Molmil
Crystal Structure of CutA1 from Pyrococcus Horikoshii
Descriptor: 102AA long hypothetical periplasmic divalent cation tolerance protein CUTA
Authors:Tanaka, Y, Sakai, N, Yasutake, Y, Yao, M, Tsumoto, K, Kumagai, I, Tanaka, I.
Deposit date:2003-01-11
Release date:2004-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural implications for heavy metal-induced reversible assembly and aggregation of a protein: the case of Pyrococcus horikoshii CutA.
Febs Lett., 556, 2004
3VTM
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BU of 3vtm by Molmil
Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin
Descriptor: GLYCEROL, Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING INDIUM
Authors:Vu, N.T, Caaveiro, J.M.M, Moriwaki, Y, Tsumoto, K.
Deposit date:2012-05-31
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus
Protein Sci., 22, 2013
1WT5
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BU of 1wt5 by Molmil
The Crystal Structure Of A Humanized Antibody Fv 528
Descriptor: ANTI EGFR ANTIBODY FV REGION
Authors:Makabe, K, Tsumoto, K, Asano, R, Kondo, H, Kumagai, I.
Deposit date:2004-11-16
Release date:2005-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528
J.Biol.Chem., 283, 2008
3VUA
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BU of 3vua by Molmil
Apo IsdH-NEAT3 in space group P3121 at a resolution of 1.85 A
Descriptor: ACETATE ION, GLYCEROL, Iron-regulated surface determinant protein H, ...
Authors:Vu, N.T, Caaveiro, J.M.M, Moriwaki, Y, Tsumoto, K.
Deposit date:2012-06-26
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin
To be Published
2Z4Q
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BU of 2z4q by Molmil
Crystal structure of a murine antibody FAB 528
Descriptor: CADMIUM ION, CHLORIDE ION, anti egfr antibody fab, ...
Authors:Nakanishi, T, Tsumoto, K, Asano, R, Kondo, H, Kumagai, I.
Deposit date:2007-06-22
Release date:2007-10-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528
J.Biol.Chem., 283, 2008
7CUE
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BU of 7cue by Molmil
Crystal structure of HID2 bound to human Hemoglobin
Descriptor: Amino acid ABC transporter substrate-binding protein, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Caaveiro, J.M.M, Hoshino, M, Tsumoto, K.
Deposit date:2020-08-22
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the recognition of human hemoglobin by the Shr protein from Streptococcus pyogenes
To Be Published
7CUD
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BU of 7cud by Molmil
Crystal structure of HID in the unbound form
Descriptor: Amino acid ABC transporter substrate-binding protein, BROMIDE ION
Authors:Caaveiro, J.M.M, Hoshino, M, Tsumoto, K.
Deposit date:2020-08-22
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the recognition of human hemoglobin by the Shr protein from Streptococcus pyogenes
To Be Published
7CYM
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BU of 7cym by Molmil
Crystal structure of LI-Cadherin EC1-4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Caaveiro, J.M.M, Yui, A, Tsumoto, K.
Deposit date:2020-09-03
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
5YQ5
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BU of 5yq5 by Molmil
Crystal structure of human osteomodulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Osteomodulin, PHOSPHATE ION
Authors:Caaveiro, J.M.M, Tashima, T, Tsumoto, K.
Deposit date:2017-11-05
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin.
Commun Biol, 1, 2018
4YRD
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BU of 4yrd by Molmil
Crystal structure of CapF with inhibitor 3-isopropenyl-tropolone
Descriptor: 2-hydroxy-3-(prop-1-en-2-yl)cyclohepta-2,4,6-trien-1-one, Capsular polysaccharide synthesis enzyme Cap5F, ZINC ION
Authors:Nakano, K, Chigira, T, Miyafusa, T, Nagatoishi, S, Caaveiro, J.M.M, Tsumoto, K.
Deposit date:2015-03-15
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.
Sci Rep, 5, 2015
3VWI
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BU of 3vwi by Molmil
High resolution crystal structure of FraC in the monomeric form
Descriptor: AMMONIUM ION, CHLORIDE ION, Fragaceatoxin C, ...
Authors:Tanaka, K, Morante, K, Caaveiro, J.M.M, Gonzalez-Manas, J.M, Tsumoto, K.
Deposit date:2012-08-23
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
5AZ2
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BU of 5az2 by Molmil
Crystal structure of the Fab fragment of 9E5, a murine monoclonal antibody specific for human epiregulin
Descriptor: anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain
Authors:Kado, Y, Mizohata, E, Nagatoishi, S, Iijima, M, Shinoda, K, Miyafusa, T, Nakayama, T, Yoshizumi, T, Sugiyama, A, Kawamura, T, Lee, Y.H, Matsumura, H, Doi, H, Fujitani, H, Kodama, T, Shibasaki, Y, Tsumoto, K, Inoue, T.
Deposit date:2015-09-16
Release date:2015-12-09
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
2D31
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BU of 2d31 by Molmil
Crystal structure of disulfide-linked HLA-G dimer
Descriptor: 9-mer peptide from Histone H2A, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shiroishi, M, Kuroki, K, Ose, T, Rasubala, L, Shiratori, I, Arase, H, Tsumoto, K, Kumagai, I, Kohda, D, Maenaka, K.
Deposit date:2005-09-23
Release date:2006-03-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Efficient Leukocyte Ig-like Receptor Signaling and Crystal Structure of Disulfide-linked HLA-G Dimer
J.Biol.Chem., 281, 2006
5BTQ
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BU of 5btq by Molmil
Crystal structure of human heme oxygenase 1 H25R with biliverdin bound
Descriptor: BILIVERDINE IX ALPHA, Heme oxygenase 1, SULFATE ION
Authors:Caaveiro, J.M.M, Morante, K, Sigala, P, Tsumoto, K.
Deposit date:2015-06-03
Release date:2016-06-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis
Biochemistry, 55, 2016
5BPG
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BU of 5bpg by Molmil
Crystal structure of the water-soluble FraC purified starting from the trans-membrane pore
Descriptor: CHLORIDE ION, Fragaceatoxin C, GLYCEROL
Authors:Caaveiro, J.M.M, Tanaka, K, Tsumoto, K.
Deposit date:2015-05-28
Release date:2015-11-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Bidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native States
Biochemistry, 54, 2015

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