8DFA
| type I-C Cascade bound to ssDNA target | Descriptor: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | Deposit date: | 2022-06-21 | Release date: | 2023-02-22 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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8DFS
| type I-C Cascade bound to AcrIF2 | Descriptor: | Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ... | Authors: | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | Deposit date: | 2022-06-22 | Release date: | 2023-02-22 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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2DFS
| 3-D structure of Myosin-V inhibited state | Descriptor: | Calmodulin, Myosin-5A | Authors: | Liu, J, Taylor, D.W, Krementsova, E.B, Trybus, K.M, Taylor, K.A. | Deposit date: | 2006-03-03 | Release date: | 2006-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON CRYSTALLOGRAPHY (24 Å) | Cite: | Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography Nature, 442, 2006
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6N8L
| Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8M
| Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | Descriptor: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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6N8N
| Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | Descriptor: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | Authors: | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | Deposit date: | 2018-11-29 | Release date: | 2019-03-13 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
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7S4V
| Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | Authors: | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | Deposit date: | 2021-09-09 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
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4CMP
| Crystal structure of S. pyogenes Cas9 | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | Authors: | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | Deposit date: | 2014-01-16 | Release date: | 2014-02-12 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation. Science, 343, 2014
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4CMQ
| Crystal structure of Mn-bound S.pyogenes Cas9 | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | Authors: | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | Deposit date: | 2014-01-17 | Release date: | 2014-02-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation Science, 343, 2014
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7JHY
| Type IV-B CRISPR Complex | Descriptor: | Csf2 (Cas7), Csf4 (Cas11), RNA (31-MER) | Authors: | Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2020-07-21 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of a type IV CRISPR-Cas ribonucleoprotein complex. Iscience, 24, 2021
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7L1F
| SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate | Descriptor: | Non-structural protein 7, Non-structural protein 8, RNA (5'-R(P*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*UP*UP*AP*G)-3'), ... | Authors: | Bravo, J.P.K, Taylor, D.W. | Deposit date: | 2020-12-14 | Release date: | 2021-02-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. Mol.Cell, 81, 2021
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6BIH
| The Structure of the Actin-Smooth Muscle Myosin Motor Domain Complex in the Rigor State | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Taylor, K.A, Banerjee, C, Hu, Z. | Deposit date: | 2017-11-02 | Release date: | 2018-09-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | The structure of the actin-smooth muscle myosin motor domain complex in the rigor state. J. Struct. Biol., 200, 2017
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3J04
| EM structure of the heavy meromyosin subfragment of Chick smooth muscle Myosin with regulatory light chain in phosphorylated state | Descriptor: | Myosin light polypeptide 6, Myosin regulatory light chain 2, smooth muscle major isoform, ... | Authors: | Baumann, B.A.J, Taylor, D, Huang, Z, Tama, F, Fagnant, P.M, Trybus, K, Taylor, K. | Deposit date: | 2011-02-18 | Release date: | 2011-11-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation. J.Mol.Biol., 415, 2012
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4OGC
| Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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4OGE
| Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii | Descriptor: | HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... | Authors: | Jiang, F, Ma, E, Lin, S, Doudna, J.A. | Deposit date: | 2014-01-15 | Release date: | 2014-02-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
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5F9R
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3V7A
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7KOG
| Lethocerus Myosin II complete coiled-coil domain resolved in its native environment | Descriptor: | Myosin heavy chain isoform Mhc_X1 | Authors: | Rahmani, H, Hu, Z, Daneshparvar, N, Taylor, D, Taylor, K.A. | Deposit date: | 2020-11-09 | Release date: | 2021-03-24 | Last modified: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | The myosin II coiled-coil domain atomic structure in its native environment. Proc.Natl.Acad.Sci.USA, 118, 2021
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7KHA
| Cryo-EM Structure of the Desulfovibrio vulgaris Type I-C Apo Cascade | Descriptor: | CRISPR-associated protein, CT1133 family, CT1134 family, ... | Authors: | O'Brien, R, Wrapp, D, Bravo, J.P.K, Schwartz, E, Taylor, D. | Deposit date: | 2020-10-20 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis for assembly of non-canonical small subunits into type I-C Cascade. Nat Commun, 11, 2020
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