4GZC
 
 | |
4GZD
 | |
4I56
 | | HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa | | Descriptor: | (3S,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8,21-trimethyl-10,14-dioxo-19-thioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | Authors: | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Crichelow, C.J, Rodwell, V.W, Wrensford, L.V, Min, J, Burgner II, J.W. | | Deposit date: | 2012-11-28 | | Release date: | 2013-07-17 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
|
|
4I64
 | | 3-hydroxy-3-methylglutaryl Coenzyme A reductase from Pseudomonas mevalonii, a high resolution native structure | | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | Authors: | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | Deposit date: | 2012-11-29 | | Release date: | 2013-07-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
|
|
4I6A
 | | 3-hydroxy-3-methylglutaryl (HMG) Coenzyme A reductase from Pseudomonas mevalonii complexed with HMG-CoA | | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | Authors: | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | Deposit date: | 2012-11-29 | | Release date: | 2013-07-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
|
|
4I6W
 | | 3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate | | Descriptor: | (3S)-3-hydroxy-3-methyl-5-sulfanylpentanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | Authors: | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | Deposit date: | 2012-11-30 | | Release date: | 2013-07-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
|
|
4I6Y
 | | 3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate | | Descriptor: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, ... | | Authors: | Steussy, C.N, Stauffacher, C.V, Schmidt, T, Burgner II, J.W, Rodwell, V.W, Wrensford, L.V, Critchelow, C.J, Min, J. | | Deposit date: | 2012-11-30 | | Release date: | 2013-07-17 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
Biochemistry, 52, 2013
|
|
1NY7
 | | COWPEA MOSAIC VIRUS (CPMV) | | Descriptor: | COWPEA MOSAIC VIRUS, LARGE (L) SUBUNIT, SMALL (S) SUBUNIT | | Authors: | Lin, T, Chen, Z, Usha, R, Stauffacher, C.V, Dai, J.-B, Schmidt, T, Johnson, J.E. | | Deposit date: | 2003-02-11 | | Release date: | 2003-03-18 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Refined Crystal Structure of Cowpea Mosaic Virus at 2.8A Resolution
Virology, 265, 1999
|
|
1PNT
 | |
1YSL
 | | Crystal structure of HMG-CoA synthase from Enterococcus faecalis with AcetoAcetyl-CoA ligand. | | Descriptor: | ACETOACETIC ACID, COENZYME A, GLYCEROL, ... | | Authors: | Steussy, C.N, Vartia, A.A, Burgner II, J.W, Sutherlin, A, Rodwell, V.W, Stauffacher, C.V. | | Deposit date: | 2005-02-08 | | Release date: | 2005-11-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray Crystal Structures of HMG-CoA Synthase from Enterococcus faecalis and a Complex with Its Second Substrate/Inhibitor Acetoacetyl-CoA.
Biochemistry, 44, 2005
|
|
1Z12
 | | Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Vanadate | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION | | Authors: | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | Deposit date: | 2005-03-03 | | Release date: | 2005-04-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
|
|
1Z13
 | | Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Molybdate | | Descriptor: | Low molecular weight phosphotyrosine protein phosphatase, MOLYBDATE ION | | Authors: | Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V. | | Deposit date: | 2005-03-03 | | Release date: | 2005-04-05 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
|
|
1P8A
 | |
1QAY
 | | TERNARY COMPLEX OF PSEUDOMONAS MEVALONII HMG-COA REDUCTASE WITH MEVALONATE AND NAD+ | | Descriptor: | (R)-MEVALONATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE) | | Authors: | Tabernero, L, Bochar, D.A, Rodwell, V.W, Stauffacher, C.V. | | Deposit date: | 1999-04-07 | | Release date: | 1999-06-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1QAX
 | | TERNARY COMPLEX OF PSEUDOMONAS MEVALONII HMG-COA REDUCTASE WITH HMG-COA AND NAD+ | | Descriptor: | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE) | | Authors: | Tabernero, L, Bochar, D.A, Rodwell, V.W, Stauffacher, C.V. | | Deposit date: | 1999-04-06 | | Release date: | 1999-06-18 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1R7I
 | | HMG-CoA Reductase from P. mevalonii, native structure at 2.2 angstroms resolution. | | Descriptor: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, GLYCEROL, SULFATE ION | | Authors: | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | | Deposit date: | 2003-10-21 | | Release date: | 2003-11-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-COA Reductase.
To be Published
|
|
1R31
 | | HMG-CoA reductase from Pseudomonas mevalonii complexed with HMG-CoA | | Descriptor: | (R)-MEVALONATE, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, ... | | Authors: | Watson, J.M, Steussy, C.N, Burgner, J.W, Lawrence, C.M, Tabernero, L, Rodwell, V.W, Stauffacher, C.V. | | Deposit date: | 2003-09-30 | | Release date: | 2003-10-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Investigations of the Basis for Stereoselectivity from the Binary Complex of HMG-CoA Reductase.
To be Published
|
|
5PNT
 | | CRYSTAL STRUCTURE OF A HUMAN LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE. IMPLICATIONS FOR SUBSTRATE SPECIFICITY | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LOW MOLECULAR WEIGHT PHOSPHOTYROSYL PHOSPHATASE | | Authors: | Zhang, M, Stauffacher, C, Lin, D, Vanetten, R. | | Deposit date: | 1998-04-29 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity.
J.Biol.Chem., 273, 1998
|
|
1T02
 | | Crystal structure of a Statin bound to class II HMG-CoA reductase | | Descriptor: | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | | Authors: | Tabernero, L, Rodwell, V.W, Stauffacher, C. | | Deposit date: | 2004-04-07 | | Release date: | 2004-08-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
J.Biol.Chem., 278, 2003
|
|
1JCK
 | |
1D1Q
 | | CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) COMPLEXED WITH THE SUBSTRATE PNPP | | Descriptor: | 4-NITROPHENYL PHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Wang, S, Tabernero, L, Zhang, M, Harms, E, Van Etten, R.L, Staufacher, C.V. | | Deposit date: | 1999-09-20 | | Release date: | 2000-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Biochemistry, 39, 2000
|
|
7M66
 | |
1AC6
 | |
