4I6Y

3-hydroxy-3-methyl (HMG) Coenzyme A Reductase bound to R-Mevalonate

Summary for 4I6Y

Entry DOI	10.2210/pdb4i6y/pdb
Related	4I4B 4I56 4I64 4I6A 4I6W
Descriptor	3-hydroxy-3-methylglutaryl-coenzyme A reductase, (R)-MEVALONATE, GLYCEROL, ... (6 entities in total)
Functional Keywords	oxidoreductase
Biological source	Pseudomonas mevalonii
Total number of polymer chains	2
Total formula weight	92567.54
Authors	Steussy, C.N.,Stauffacher, C.V.,Schmidt, T.,Burgner II, J.W.,Rodwell, V.W.,Wrensford, L.V.,Critchelow, C.J.,Min, J. (deposition date: 2012-11-30, release date: 2013-07-17, Last modification date: 2019-07-17)
Primary citation	Steussy, C.N.,Critchelow, C.J.,Schmidt, T.,Min, J.K.,Wrensford, L.V.,Burgner, J.W.,Rodwell, V.W.,Stauffacher, C.V. A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase. Biochemistry, 52:5195-5205, 2013 Cited by PubMed: 23802607 DOI: 10.1021/bi400335g PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation