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4DOV
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BU of 4dov by Molmil
Structure of free mouse ORC1 BAH domain
Descriptor: Origin recognition complex subunit 1
Authors:Song, J, Patel, D.J.
Deposit date:2012-02-10
Release date:2012-03-07
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature, 484, 2012
4DOW
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BU of 4dow by Molmil
Structure of mouse ORC1 BAH domain bound to H4K20me2
Descriptor: Histone H4, Origin recognition complex subunit 1
Authors:Song, J, Patel, D.J.
Deposit date:2012-02-10
Release date:2012-03-07
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome.
Nature, 484, 2012
4K6L
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BU of 4k6l by Molmil
Structure of Typhoid Toxin
Descriptor: Cytolethal distending toxin subunit B homolog, GLYCEROL, Putative pertussis-like toxin subunit
Authors:Gao, X, Song, J, Galan, J.
Deposit date:2013-04-16
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin.
Nature, 499, 2013
5EXH
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BU of 5exh by Molmil
Crystal structure of mTET3-CXXC domain in complex with 5-carboxylcytosine DNA at 1.3 Angstroms resolution.
Descriptor: DNA (5'-D(*GP*AP*AP*TP*CP*(1CC)P*GP*GP*AP*TP*TP*C)-3'), Methylcytosine dioxygenase TET3, ZINC ION
Authors:Song, J.
Deposit date:2015-11-23
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration.
Cell Rep, 14, 2016
5W3T
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BU of 5w3t by Molmil
Crystal structure of PopP2 in complex with IP6
Descriptor: GLYCEROL, INOSITOL HEXAKISPHOSPHATE, PopP2 protein
Authors:Song, J, Zhang, Z.M.
Deposit date:2017-06-08
Release date:2017-08-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Mechanism of host substrate acetylation by a YopJ family effector.
Nat Plants, 3, 2017
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
Descriptor: Histone demethylase JARID1A, ZINC ION
Authors:Song, J, Wang, Z, Patel, D.J.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KGI
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BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
Descriptor: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
Authors:Song, J, Wang, Z, Patel, D.J.
Deposit date:2009-03-12
Release date:2009-05-05
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KU7
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BU of 2ku7 by Molmil
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
Descriptor: MLL1 PHD3-Cyp33 RRM chimeric protein
Authors:Song, J, Wang, Z, Patel, D.
Deposit date:2010-02-12
Release date:2010-07-07
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
2M0O
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BU of 2m0o by Molmil
The solution structure of human PHF1 in complex with H3K36me3
Descriptor: H3K36me3 peptide, PHD finger protein 1
Authors:Song, J, Patel, D.J.
Deposit date:2012-10-30
Release date:2013-01-16
Last modified:2013-02-27
Method:SOLUTION NMR
Cite:An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013
5HDA
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BU of 5hda by Molmil
Crystal Structure of the BS69 coiled coil-MYND domains bound to an EBNA2 PXLXP motif
Descriptor: Epstein-Barr nuclear antigen 2, ZINC ION, Zinc finger MYND domain-containing protein 11
Authors:Song, J, Harter, M.
Deposit date:2016-01-05
Release date:2016-01-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3899 Å)
Cite:BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2.
Plos Pathog., 12, 2016
6B9M
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BU of 6b9m by Molmil
Crystal structure of UHRF1 TTD domain in complex with the polybasic region
Descriptor: E3 ubiquitin-protein ligase UHRF1
Authors:Song, J, Tan, X.
Deposit date:2017-10-10
Release date:2018-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association.
Structure, 26, 2018
6B9L
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BU of 6b9l by Molmil
Crystal structure of EphA2 with peptide 135E2
Descriptor: Ephrin type-A receptor 2, HIS TAG CLEAVED OFF, peptide 135E2, ...
Authors:Song, J, Tan, X.
Deposit date:2017-10-10
Release date:2018-10-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.
ACS Chem. Biol., 13, 2018
7UBU
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BU of 7ubu by Molmil
Crystal structure of ZMET2 in complex with hemimethylated CAG DNA and a histone H3Kc9me2 peptide
Descriptor: 5MC SSDNA, C49 SSDNA, DNA (cytosine-5)-methyltransferase 1, ...
Authors:Fang, J, Song, J.
Deposit date:2022-03-15
Release date:2022-06-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Mechanistic basis for maintenance of CHG DNA methylation in plants.
Nat Commun, 13, 2022
8FZB
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BU of 8fzb by Molmil
Crystal structure of human FAM86A
Descriptor: Protein-lysine N-methyltransferase EEF2KMT, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Shao, Z, Lu, J, Song, J.
Deposit date:2023-01-28
Release date:2023-06-21
Last modified:2023-06-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The FAM86 domain of FAM86A confers substrate specificity to promote EEF2-Lys525 methylation.
J.Biol.Chem., 299, 2023
8T1U
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BU of 8t1u by Molmil
Crystal structure of the DRM2-CTA DNA complex
Descriptor: DNA (5'-D(P*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*AP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*TP*TP*TP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Chen, J, Lu, J, Song, J.
Deposit date:2023-06-03
Release date:2023-11-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2.
J.Biol.Chem., 299, 2023
6F57
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BU of 6f57 by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with single CpG-containing DNA
Descriptor: DNA (5'-D(*AP*GP*AP*GP*CP*GP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*ZP*GP*CP*TP*CP*T)-3'), DNA (cytosine-5)-methyltransferase 3-like, ...
Authors:Zhang, Z.M, Song, J.
Deposit date:2017-12-01
Release date:2018-01-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Structural basis for DNMT3A-mediated de novo DNA methylation.
Nature, 554, 2018
7SUO
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BU of 7suo by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein
Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
Authors:Biswal, M, Lu, J, Song, J.
Deposit date:2021-11-17
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:SARS-CoV-2 Nucleocapsid Protein Targets a Conserved Surface Groove of the NTF2-like Domain of G3BP1.
J.Mol.Biol., 434, 2022
6W8D
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BU of 6w8d by Molmil
Structure of DNMT3A (R882H) in complex with CGT DNA
Descriptor: CGT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ...
Authors:Anteneh, H, Song, J.
Deposit date:2020-03-20
Release date:2020-04-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation.
Nat Commun, 11, 2020
7L4C
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BU of 7l4c by Molmil
Crystal structure of the DRM2-CTT DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*TP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-18
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4K
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BU of 7l4k by Molmil
Crystal structure of the DRM2-CCG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4H
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BU of 7l4h by Molmil
Crystal structure of the DRM2-CTG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*TP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*AP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4N
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BU of 7l4n by Molmil
Crystal structure of the DRM2 (C397R)-CCG DNA complex
Descriptor: DNA (5'-D(*AP*TP*TP*CP*CP*TP*AP*AP*TP*(C49)P*CP*GP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*TP*TP*CP*GP*GP*AP*TP*TP*AP*GP*GP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.247 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4M
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BU of 7l4m by Molmil
Crystal structure of the DRM2-CCT DNA complex
Descriptor: DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*CP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (cytosine-5)-methyltransferase DRM2, ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
7L4F
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BU of 7l4f by Molmil
Crystal structure of the DRM2-CAT DNA complex
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*AP*TP*TP*CP*CP*TP*CP*CP*TP*(C49)P*AP*TP*CP*CP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*GP*GP*AP*TP*GP*AP*GP*GP*AP*GP*GP*AP*AP*T)-3'), ...
Authors:Fang, J, Song, J.
Deposit date:2020-12-19
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Substrate deformation regulates DRM2-mediated DNA methylation in plants.
Sci Adv, 7, 2021
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Descriptor: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
Authors:Ren, W, Song, J.
Deposit date:2019-08-01
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020

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