6B9L

Crystal structure of EphA2 with peptide 135E2

Summary for 6B9L

• Entry DOI: 10.2210/pdb6b9l/pdb
• Descriptor: Ephrin type-A receptor 2, peptide 135E2, (DUG)SAYPDSVPFR, HIS TAG CLEAVED OFF (3 entities in total)
• Functional Keywords: complex, ligand binding domain, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 9
• Total formula weight: 94920.75

Authors

Song, J.,Tan, X. (deposition date: 2017-10-10, release date: 2018-10-17)

• Primary citation: Gambini, L.,Salem, A.F.,Udompholkul, P.,Tan, X.F.,Baggio, C.,Shah, N.,Aronson, A.,Song, J.,Pellecchia, M.; Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.; ACS Chem. Biol., 13:2633-2644, 2018; PubMed: 30110533; DOI: 10.1021/acschembio.8b00556

Experimental method

X-RAY DIFFRACTION (3.2 Å)