6SFT
| Solution structure of protein ARR_CleD in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Two-component receiver protein CleD | Authors: | Habazettl, J, Hee, C.S, Jenal, U, Schirmer, T, Grzesiek, S. | Deposit date: | 2019-08-02 | Release date: | 2020-06-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Intercepting second-messenger signaling by rationally designed peptides sequestering c-di-GMP. Proc.Natl.Acad.Sci.USA, 117, 2020
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6TTR
| Crystal Structure of the coiled coil and GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF diguanylate cyclase DgcB, PHOSPHATE ION | Authors: | Holzschuh, F, Schirmer, T, Teixeira, R.D. | Deposit date: | 2019-12-30 | Release date: | 2021-01-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of the coiled coil and GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP To Be Published
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6TTS
| Crystal structure of the GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF diguanylate cyclase DgcB, SULFATE ION | Authors: | Holzschuh, F, Schirmer, T, Teixeira, R. | Deposit date: | 2019-12-30 | Release date: | 2021-01-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the GGDEF domain of DgcB from Caulobacter crescentus in complex with c-di-GMP To Be Published
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2WPU
| Chaperoned ruthenium metallodrugs that recognize telomeric DNA | Descriptor: | (3AS,4S,6AR)-4-(5-((3R,4R)-3,4-DIAMINOPYRROLIDIN-1-YL)-5-OXOPENTYL)TETRAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-2(3H)-ONE-P-CYMENE-CHLORO-RUTHENIUM(III), GLYCEROL, STREPTAVIDIN, ... | Authors: | Heinisch, T, Schirmer, T, Zimbron, J.M, Sardo, A, Wohlschlager, T, Gradinaru, J, Creus, M, Ward, T.R. | Deposit date: | 2009-08-10 | Release date: | 2010-10-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Chemo-Genetic Optimization of DNA Recognition by Metallodrugs Using a Presenter-Protein Strategy. Chemistry, 16, 2010
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4KIE
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1OHW
| 4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-vinyl GABA | Descriptor: | 4-AMINO HEXANOIC ACID, 4-AMINOBUTYRATE AMINOTRANSFERASE, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Storici, P, Schirmer, T. | Deposit date: | 2003-06-03 | Release date: | 2003-10-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of {Gamma}-Aminobutyric Acid (Gaba) Aminotransferase, a Pyridoxal 5'-Phosphate, and [2Fe-2S] Cluster-Containing Enzyme, Complexed with {Gamma}-Ethynyl-Gaba and with the Antiepilepsy Drug Vigabatrin J.Biol.Chem., 279, 2004
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1OHY
| 4-AMINOBUTYRATE-AMINOTRANSFERASE inactivated by gamma-ethynyl GABA | Descriptor: | (4E)-4-AMINOHEX-4-ENOIC ACID, 4-AMINOBUTYRATE AMINOTRANSFERASE, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Storici, P, Schirmer, T. | Deposit date: | 2003-06-03 | Release date: | 2003-10-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of {Gamma}-Aminobutyric Acid (Gaba) Aminotransferase, a Pyridoxal 5'-Phosphate, and [2Fe-2S] Cluster-Containing Enzyme, Complexed with {Gamma}-Ethynyl-Gaba and with the Antiepilepsy Drug Vigabatrin J.Biol.Chem., 279, 2004
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1OHV
| 4-AMINOBUTYRATE-AMINOTRANSFERASE FROM PIG | Descriptor: | 4-AMINOBUTYRATE AMINOTRANSFERASE, ACETATE ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Storici, P, Schirmer, T. | Deposit date: | 2003-06-02 | Release date: | 2003-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of {Gamma}-Aminobutyric Acid (Gaba) Aminotransferase, a Pyridoxal 5'-Phosphate, and [2Fe-2S] Cluster-Containing Enzyme, Complexed with {Gamma}-Ethynyl-Gaba and with the Antiepilepsy Drug Vigabatrin J.Biol.Chem., 279, 2004
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4LJ3
| Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++ | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Cyclic di-GMP phosphodiesterase YahA, ... | Authors: | Sundriyal, A, Schirmer, T. | Deposit date: | 2013-07-04 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Inherent Regulation of EAL Domain-catalyzed Hydrolysis of Second Messenger Cyclic di-GMP. J.Biol.Chem., 289, 2014
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4LYK
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2J88
| Hyaluronidase in complex with a monoclonal IgG Fab fragment | Descriptor: | FAB, HYALURONONGLUCOSAMINIDASE | Authors: | Padavattan, S, Schirmer, T, Markovic-Housley, Z. | Deposit date: | 2006-10-23 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Identification of a B-Cell Epitope of Hyaluronidase, a Major Bee Venom Allergen, from its Crystal Structure in Complex with a Specific Fab. J.Mol.Biol., 368, 2007
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2J1N
| osmoporin OmpC | Descriptor: | CHLORIDE ION, DODECANE, MAGNESIUM ION, ... | Authors: | Basle, A, Storici, P, Rummel, G, Rosenbusch, J.P, Schirmer, T. | Deposit date: | 2006-08-15 | Release date: | 2006-09-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Osmoporin Ompc from E. Coli at 2.0 A. J.Mol.Biol., 362, 2006
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2JK8
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1W25
| Response regulator PleD in complex with c-diGMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, STALKED-CELL DIFFERENTIATION CONTROLLING PROTEIN, ... | Authors: | Chan, C, Schirmer, T, Jenal, U. | Deposit date: | 2004-06-28 | Release date: | 2004-11-18 | Last modified: | 2019-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Activity and Allosteric Control of Diguanylate Cyclase Proc.Natl.Acad.Sci.USA, 101, 2004
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1MPM
| MALTOPORIN MALTOSE COMPLEX | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Dutzler, R, Schirmer, T. | Deposit date: | 1996-01-11 | Release date: | 1997-03-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway. Structure, 4, 1996
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1MPN
| MALTOPORIN MALTOTRIOSE COMPLEX | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Dutzler, R, Schirmer, T. | Deposit date: | 1996-01-11 | Release date: | 1997-03-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway. Structure, 4, 1996
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1MPO
| MALTOPORIN MALTOHEXAOSE COMPLEX | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Dutzler, R, Schirmer, T. | Deposit date: | 1996-01-11 | Release date: | 1997-03-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway. Structure, 4, 1996
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4FQE
| KdgM porin | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-OCTANE, Oligogalacturonate-specific porin kdgM | Authors: | Hutter, C, Peneff, C.M, Wirth, C, Schirmer, T. | Deposit date: | 2012-06-25 | Release date: | 2013-06-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure of the oligogalacturonate-specific KdgM porin. Acta Crystallogr.,Sect.D, 70, 2014
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4H54
| Crystal structure of the diguanylate cyclase DgcZ | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate cyclase YdeH, GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, ... | Authors: | Zaehringer, F, Schirmer, T. | Deposit date: | 2012-09-18 | Release date: | 2013-07-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure and signaling mechanism of a zinc-sensory diguanylate cyclase. Structure, 21, 2013
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4HJF
| EAL domain of phosphodiesterase PdeA in complex with c-di-GMP and Ca++ | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, GGDEF family protein | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-10-12 | Release date: | 2012-10-31 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of EAL domain from Caulobacter crescentus in complex with c-di-GMP and Ca TO BE PUBLISHED
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4PGL
| Crystal structure of engineered D-tagatose 3-epimerase PcDTE-ILS6 | Descriptor: | D-tagatose 3-epimerase, L-sorbose, L-tagatose, ... | Authors: | Hee, C.S, Bosshart, A, Schirmer, T. | Deposit date: | 2014-05-02 | Release date: | 2014-10-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates. Chembiochem, 16, 2015
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4PRX
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4PU9
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4PR7
| KdgM porin in complex with disordered oligogalacturonate | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, N-OCTANE, Oligogalacturonate-specific porin KdgM, ... | Authors: | Hutter, C, Peneff, C.M, Wirth, C, Schirmer, T. | Deposit date: | 2014-03-05 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the oligogalacturonate-specific KdgM porin. Acta Crystallogr.,Sect.D, 70, 2014
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4PFH
| Crystal structure of engineered D-tagatose 3-epimerase PcDTE-IDF8 | Descriptor: | D-fructose, D-psicose, D-tagatose 3-epimerase, ... | Authors: | Hee, C.S, Bosshart, A, Schirmer, T. | Deposit date: | 2014-04-29 | Release date: | 2014-10-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Directed Divergent Evolution of a Thermostable D-Tagatose Epimerase towards Improved Activity for Two Hexose Substrates. Chembiochem, 16, 2015
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