1TPY
 
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1UCK
 | | Mutants of RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | | Deposit date: | 2003-04-15 | | Release date: | 2003-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
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1UCJ
 | | Mutants of RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | | Deposit date: | 2003-04-15 | | Release date: | 2003-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
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1UCL
 | | Mutants of RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | | Deposit date: | 2003-04-15 | | Release date: | 2003-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
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1UCI
 | | Mutants of RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | | Deposit date: | 2003-04-15 | | Release date: | 2003-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
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1VA5
 | | Antigen 85C with octylthioglucoside in active site | | Descriptor: | Antigen 85-C, octyl 1-thio-beta-D-glucopyranoside | | Authors: | Ronning, D.R, Vissa, V, Besra, G.S, Belisle, J.T, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-02-11 | | Release date: | 2004-07-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Mycobacterium tuberculosis Antigen 85A and 85C Structures Confirm Binding Orientation and Conserved Substrate Specificity
J.Biol.Chem., 279, 2004
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1VRW
 | | Crystal structure analysis of plasmodium falciparum enoyl-acyl-carrier-protein reductase with nadh | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ENOYL-ACYL CARRIER REDUCTASE | | Authors: | Perozzo, R, Kuo, M, Sidhu, A.S, Valiyaveettil, J.T, Bittman, R, Jacobs Jr, W.R, Fidock, D.A, Sacchettini, J.C. | | Deposit date: | 2005-06-30 | | Release date: | 2005-07-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for
Malarial Enoyl Acyl Carrier Protein Reductase
J.Biol.Chem., 277, 2002
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1XJU
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1XJT
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1Y4Y
 | | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) | | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | | Deposit date: | 2004-12-01 | | Release date: | 2005-02-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
J.Mol.Biol., 346, 2005
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1Y50
 | | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant domain_swapped dimer | | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | | Deposit date: | 2004-12-01 | | Release date: | 2005-02-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
J.Mol.Biol., 346, 2005
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1Y8T
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1Y51
 | | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant | | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | | Deposit date: | 2004-12-01 | | Release date: | 2005-02-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
J.Mol.Biol., 346, 2005
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1Y6X
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1YNK
 | | Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647 | | Descriptor: | 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL, Ig gamma heavy chain, immunoglobulin kappa light chain | | Authors: | Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B. | | Deposit date: | 2005-01-24 | | Release date: | 2005-08-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
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3BV0
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3BZQ
 | | High resolution crystal structure of Nitrogen Regulatory Protein (Rv2919c) of Mycobacterium tuberculosis | | Descriptor: | Nitrogen regulatory protein P-II | | Authors: | Reddy, M.C, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-01-18 | | Release date: | 2008-04-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein.
Protein Sci., 19, 2010
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3C90
 | | The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II | | Descriptor: | Phosphoribosyl-ATP pyrophosphatase | | Authors: | Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-02-14 | | Release date: | 2008-04-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 64, 2008
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3CE6
 | | Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and adenosine | | Descriptor: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Reddy, M.C.M, Gokulan, K, Shetty, N.D, Owen, J.L, Ioerger, T.R, Sacchettini, J.C. | | Deposit date: | 2008-02-28 | | Release date: | 2008-09-16 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.
Protein Sci., 17, 2008
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3D7P
 | | Crystal structure of human Transthyretin (TTR) at pH 4.0 | | Descriptor: | Transthyretin | | Authors: | Palaninathan, S.K, Mohamedmohaideen, N.N, Snee, W.C, Kelly, J.W, Sacchettini, J.C. | | Deposit date: | 2008-05-21 | | Release date: | 2008-08-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.
J.Mol.Biol., 382, 2008
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3D2T
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3DC2
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3DDN
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3DHY
 | | Crystal Structures of Mycobacterium tuberculosis S-Adenosyl-L-Homocysteine Hydrolase in Ternary Complex with Substrate and Inhibitors | | Descriptor: | 5'-S-ethyl-5'-thioadenosine, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Shetty, N.D, Ioerger, T.R, Gokulan, K, Reddy, M.C.M, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-06-19 | | Release date: | 2008-09-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.
Protein Sci., 17, 2008
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3DOD
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