1VRW

Crystal structure analysis of plasmodium falciparum enoyl-acyl-carrier-protein reductase with nadh

Replaces:  1NHD

Summary for 1VRW

• Entry DOI: 10.2210/pdb1vrw/pdb
• Descriptor: ENOYL-ACYL CARRIER REDUCTASE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (2 entities in total)
• Functional Keywords: rossmann fold, short chain dehydrogenase reductase, nadh, oxidoreductase
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum)
• Total number of polymer chains: 2
• Total formula weight: 77522.80

Authors

Perozzo, R.,Kuo, M.,Sidhu, A.S.,Valiyaveettil, J.T.,Bittman, R.,Jacobs Jr., W.R.,Fidock, D.A.,Sacchettini, J.C. (deposition date: 2005-06-30, release date: 2005-07-05, Last modification date: 2023-12-27)

• Primary citation: Perozzo, R.,Kuo, M.,Sidhu, A.S.,Valiyaveettil, J.T.,Bittman, R.,Jacobs Jr., W.R.,Fidock, D.A.,Sacchettini, J.C.; Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase; J.Biol.Chem., 277:13106-13114, 2002; PubMed: 11792710; DOI: 10.1074/jbc.M112000200

Experimental method

X-RAY DIFFRACTION (2.4 Å)