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3NZW
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BU of 3nzw by Molmil
Crystal structure of the yeast 20S proteasome in complex with 2b
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, Proteasome component C11, ...
著者Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M.
登録日2010-07-17
公開日2011-02-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZJ
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BU of 3nzj by Molmil
Crystal structure of yeast 20S proteasome in complex with ligand 2a
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, Proteasome component C11, ...
著者Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M.
登録日2010-07-16
公開日2011-02-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
3NZX
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BU of 3nzx by Molmil
Crystal structure of the yeast 20S proteasome in complex with ligand 2c
分子名称: Proteasome component C1, Proteasome component C11, Proteasome component C5, ...
著者Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M.
登録日2010-07-17
公開日2011-02-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A.
Chemmedchem, 5, 2010
4JSU
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BU of 4jsu by Molmil
Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:3a
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Desvergne, A, Genin, E, Marechal, X, Gallastegui, N, Dufau, L, Richy, N, Groll, M, Vidal, J, Reboud-Ravaux, M.
登録日2013-03-22
公開日2013-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome
J.Med.Chem., 56, 2013
4JSQ
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BU of 4jsq by Molmil
Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4e
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Desvergne, A, Genin, E, Marechal, X, Gallastegui, N, Dufau, L, Richy, N, Groll, M, Vidal, J, Reboud-Ravaux, M.
登録日2013-03-22
公開日2013-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome
J.Med.Chem., 56, 2013
4JT0
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BU of 4jt0 by Molmil
Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4a
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ...
著者Desvergne, A, Genin, E, Marechal, X, Gallastegui, N, Dufau, L, Richy, N, Groll, M, Vidal, J, Reboud-Ravaux, M.
登録日2013-03-22
公開日2013-05-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome.
J.Med.Chem., 56, 2013
5BOU
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BU of 5bou by Molmil
Yeast 20S proteasome in complex with a beta1 / beta2 specific non-peptidic sulfonamide Ligand
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[4-(acetylsulfamoyl)phenyl]-2-(4-ethoxyphenyl)quinoline-4-carboxamide, ...
著者Beck, P, Groll, M.
登録日2015-05-27
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a beta 1/ beta 2-Specific Sulfonamide Proteasome Ligand by Crystallographic Screening.
Angew.Chem.Int.Ed.Engl., 54, 2015
6Y4S
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BU of 6y4s by Molmil
Human kallikrein-related peptidase 7 (KLK7) in the unliganded state
分子名称: Kallikrein-7, SULFATE ION, TRIETHYLENE GLYCOL
著者Hanke, S, Strater, N.
登録日2020-02-23
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SJU
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BU of 6sju by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 3 covalently bound to H57
分子名称: (3-iodanylphenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-13
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHI
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BU of 6shi by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 2 covalently bound to H57
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-2-oxidanylidene-chromene-3-carboxylic acid, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-06
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020
6SHH
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BU of 6shh by Molmil
Human kallikrein 7 with aromatic coumarinic ester compound 1 covalently bound to H57
分子名称: (3-chlorophenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Kallikrein-7, ...
著者Hanke, S, Straeter, N.
登録日2019-08-06
公開日2020-05-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
J.Med.Chem., 63, 2020

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件を2024-04-24に公開中

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