4UFL
| Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. | 登録日 | 2015-03-17 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
|
|
4UFM
| Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. | 登録日 | 2015-03-17 | 公開日 | 2015-04-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
|
|
2R82
| Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state | 分子名称: | Pyruvate, phosphate dikinase, SULFATE ION | 著者 | Lim, K, Read, R.J, Chen, C.C, Herzberg, O. | 登録日 | 2007-09-10 | 公開日 | 2008-01-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Swiveling domain mechanism in pyruvate phosphate dikinase. Biochemistry, 46, 2007
|
|
2RIV
| Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | 分子名称: | GLYCEROL, SULFATE ION, Thyroxine-binding globulin | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | 登録日 | 2007-10-12 | 公開日 | 2008-10-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
|
|
2RIW
| The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | 登録日 | 2007-10-12 | 公開日 | 2008-10-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins J.Biol.Chem., 286, 2011
|
|
2VDX
| |
2VDY
| Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | 著者 | Zhou, A, Wei, Z, Read, R.J. | 登録日 | 2007-10-13 | 公開日 | 2008-05-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
|
|
2WY1
| |
2WXW
| |
2WXX
| |
2WXY
| Crystal structure of mouse angiotensinogen in the reduced form | 分子名称: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | 著者 | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | 登録日 | 2009-11-11 | 公開日 | 2010-10-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
|
|
2WY0
| Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | 分子名称: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | 著者 | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | 登録日 | 2009-11-11 | 公開日 | 2010-10-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
|
|
2WXZ
| |
2X0B
| Crystal structure of human angiotensinogen complexed with renin | 分子名称: | ANGIOTENSINOGEN, RENIN | 著者 | Zhou, A, Wei, Z, Yan, Y, Carrell, R.W, Read, R.J. | 登録日 | 2009-12-08 | 公開日 | 2010-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.33 Å) | 主引用文献 | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
|
|
2XSC
| Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli | 分子名称: | SHIGA-LIKE TOXIN 1 SUBUNIT B, ZINC ION | 著者 | Stein, P.E, Boodhoo, A, Tyrrell, G.J, Brunton, J.L, Oeffner, R.D, Bunkoczi, G, Read, R.J. | 登録日 | 2010-09-27 | 公開日 | 2010-10-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | 主引用文献 | Crystal Structure of the Cell-Binding B Oligomer of Verotoxin-1 from E. Coli. Nature, 355, 1992
|
|
3TX8
| Crystal structure of a succinyl-diaminopimelate desuccinylase (ArgE) from Corynebacterium glutamicum ATCC 13032 at 2.97 A resolution | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase | 著者 | Joint Center for Structural Genomics (JCSG), Brunger, A.T, Terwilliger, T.C, Read, R.J, Adams, P.D, Levitt, M, Schroder, G.F. | 登録日 | 2011-09-22 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.972 Å) | 主引用文献 | Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum. Acta Crystallogr.,Sect.D, 68, 2012
|
|
3MIW
| Crystal Structure of Rotavirus NSP4 | 分子名称: | 1,2-ETHANEDIOL, Non-structural glycoprotein 4 | 著者 | Chacko, A.R, Read, R.J, Dodson, E.J, Rao, D.C, Suguna, K. | 登録日 | 2010-04-12 | 公開日 | 2011-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A new pentameric structure of rotavirus NSP4 revealed by molecular replacement. Acta Crystallogr.,Sect.D, 68, 2012
|
|
4N3E
| Crystal structure of Hyp-1, a St John's wort PR-10 protein, in complex with 8-anilino-1-naphthalene sulfonate (ANS) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-ANILINO-1-NAPHTHALENE SULFONATE, Phenolic oxidative coupling protein, ... | 著者 | Sliwiak, J, Dauter, Z, Mccoy, A.J, Read, R.J, Jaskolski, M. | 登録日 | 2013-10-07 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry. Acta Crystallogr.,Sect.D, 70, 2014
|
|
8G8F
| Human IMPDH2 mutant - L245P, treated with ATP, IMP, and NAD+; extended filament segment reconstruction | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 2, ... | 著者 | O'Neill, A.G, Kollman, J.M. | 登録日 | 2023-02-17 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
|
|
8G9B
| Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | 著者 | O'Neill, A.G, Kollman, J.M. | 登録日 | 2023-02-21 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
|
|
8H9D
| Crystal structure of Cas12a protein | 分子名称: | Cas12A, MAGNESIUM ION, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3'), ... | 著者 | Jianwei, L, Jobichen, C, Sivaraman, J. | 登録日 | 2022-10-25 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21, 2023
|
|
5M0W
| N-terminal domain of mouse Shisa 3 | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Lohkamp, B, Ojala, J.R.M. | 登録日 | 2016-10-06 | 公開日 | 2017-04-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Ab initio solution of macromolecular crystal structures without direct methods. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
8I54
| Lb2Cas12a RNA DNA complex | 分子名称: | DNA (25-MER), DNA (5'-D(*AP*GP*TP*GP*CP*TP*TP*TP*A)-3'), Lb2Cas12a, ... | 著者 | Li, J, Sivaraman, J, Satoru, M. | 登録日 | 2023-01-24 | 公開日 | 2023-02-22 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21, 2023
|
|
5MLG
| |
5MKT
| |