4N3E

Crystal structure of Hyp-1, a St John's wort PR-10 protein, in complex with 8-anilino-1-naphthalene sulfonate (ANS)

Summary for 4N3E

Entry DOI	10.2210/pdb4n3e/pdb
Related	1BV1 1FM4 1ICX 1IFV 1XDF 2FLH 2QIM 3E85 3IE5 3US7 4A80 4A81 4A83 4A85 4A86 4A87 4A8U 4A8V 4GY9 4JHG
Descriptor	Phenolic oxidative coupling protein, 8-ANILINO-1-NAPHTHALENE SULFONATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	plant hormone binding, phytohormone binding, cytokinin, plant defense, pathogenesis-related protein, pr-10 protein, hypericin, depression, pr-10 fold, hydrophobic cavity, glycine-rich loop, ans displacement assay (ada), commensurately modulated superstructure, tetartohedral twinning, plant protein
Biological source	Hypericum perforatum (St. John's wort)
Total number of polymer chains	28
Total formula weight	545269.47
Authors	Sliwiak, J.,Dauter, Z.,Mccoy, A.J.,Read, R.J.,Jaskolski, M. (deposition date: 2013-10-07, release date: 2014-02-26, Last modification date: 2023-09-20)
Primary citation	Sliwiak, J.,Jaskolski, M.,Dauter, Z.,McCoy, A.J.,Read, R.J. Likelihood-based molecular-replacement solution for a highly pathological crystal with tetartohedral twinning and sevenfold translational noncrystallographic symmetry. Acta Crystallogr.,Sect.D, 70:471-480, 2014 Cited by PubMed: 24531481 DOI: 10.1107/S1399004713030319 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.43 Å)

Structure validation