4N3E
Crystal structure of Hyp-1, a St John's wort PR-10 protein, in complex with 8-anilino-1-naphthalene sulfonate (ANS)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| a | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| a | 0005634 | cellular_component | nucleus |
| a | 0005737 | cellular_component | cytoplasm |
| a | 0006952 | biological_process | defense response |
| a | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| a | 0010427 | molecular_function | abscisic acid binding |
| a | 0038023 | molecular_function | signaling receptor activity |
| A | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006952 | biological_process | defense response |
| A | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| A | 0010427 | molecular_function | abscisic acid binding |
| A | 0038023 | molecular_function | signaling receptor activity |
| b | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| b | 0005634 | cellular_component | nucleus |
| b | 0005737 | cellular_component | cytoplasm |
| b | 0006952 | biological_process | defense response |
| b | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| b | 0010427 | molecular_function | abscisic acid binding |
| b | 0038023 | molecular_function | signaling receptor activity |
| B | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006952 | biological_process | defense response |
| B | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| B | 0010427 | molecular_function | abscisic acid binding |
| B | 0038023 | molecular_function | signaling receptor activity |
| C | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006952 | biological_process | defense response |
| C | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| C | 0010427 | molecular_function | abscisic acid binding |
| C | 0038023 | molecular_function | signaling receptor activity |
| D | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006952 | biological_process | defense response |
| D | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| D | 0010427 | molecular_function | abscisic acid binding |
| D | 0038023 | molecular_function | signaling receptor activity |
| E | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| E | 0005634 | cellular_component | nucleus |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006952 | biological_process | defense response |
| E | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| E | 0010427 | molecular_function | abscisic acid binding |
| E | 0038023 | molecular_function | signaling receptor activity |
| F | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| F | 0005634 | cellular_component | nucleus |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006952 | biological_process | defense response |
| F | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| F | 0010427 | molecular_function | abscisic acid binding |
| F | 0038023 | molecular_function | signaling receptor activity |
| G | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| G | 0005634 | cellular_component | nucleus |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006952 | biological_process | defense response |
| G | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| G | 0010427 | molecular_function | abscisic acid binding |
| G | 0038023 | molecular_function | signaling receptor activity |
| H | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| H | 0005634 | cellular_component | nucleus |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006952 | biological_process | defense response |
| H | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| H | 0010427 | molecular_function | abscisic acid binding |
| H | 0038023 | molecular_function | signaling receptor activity |
| I | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| I | 0005634 | cellular_component | nucleus |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006952 | biological_process | defense response |
| I | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| I | 0010427 | molecular_function | abscisic acid binding |
| I | 0038023 | molecular_function | signaling receptor activity |
| J | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| J | 0005634 | cellular_component | nucleus |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006952 | biological_process | defense response |
| J | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| J | 0010427 | molecular_function | abscisic acid binding |
| J | 0038023 | molecular_function | signaling receptor activity |
| K | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| K | 0005634 | cellular_component | nucleus |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006952 | biological_process | defense response |
| K | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| K | 0010427 | molecular_function | abscisic acid binding |
| K | 0038023 | molecular_function | signaling receptor activity |
| L | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| L | 0005634 | cellular_component | nucleus |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006952 | biological_process | defense response |
| L | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| L | 0010427 | molecular_function | abscisic acid binding |
| L | 0038023 | molecular_function | signaling receptor activity |
| M | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| M | 0005634 | cellular_component | nucleus |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0006952 | biological_process | defense response |
| M | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| M | 0010427 | molecular_function | abscisic acid binding |
| M | 0038023 | molecular_function | signaling receptor activity |
| N | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| N | 0005634 | cellular_component | nucleus |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0006952 | biological_process | defense response |
| N | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| N | 0010427 | molecular_function | abscisic acid binding |
| N | 0038023 | molecular_function | signaling receptor activity |
| O | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| O | 0005634 | cellular_component | nucleus |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0006952 | biological_process | defense response |
| O | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| O | 0010427 | molecular_function | abscisic acid binding |
| O | 0038023 | molecular_function | signaling receptor activity |
| P | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| P | 0005634 | cellular_component | nucleus |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0006952 | biological_process | defense response |
| P | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| P | 0010427 | molecular_function | abscisic acid binding |
| P | 0038023 | molecular_function | signaling receptor activity |
| Q | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| Q | 0005634 | cellular_component | nucleus |
| Q | 0005737 | cellular_component | cytoplasm |
| Q | 0006952 | biological_process | defense response |
| Q | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| Q | 0010427 | molecular_function | abscisic acid binding |
| Q | 0038023 | molecular_function | signaling receptor activity |
| R | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| R | 0005634 | cellular_component | nucleus |
| R | 0005737 | cellular_component | cytoplasm |
| R | 0006952 | biological_process | defense response |
| R | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| R | 0010427 | molecular_function | abscisic acid binding |
| R | 0038023 | molecular_function | signaling receptor activity |
| S | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| S | 0005634 | cellular_component | nucleus |
| S | 0005737 | cellular_component | cytoplasm |
| S | 0006952 | biological_process | defense response |
| S | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| S | 0010427 | molecular_function | abscisic acid binding |
| S | 0038023 | molecular_function | signaling receptor activity |
| T | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| T | 0005634 | cellular_component | nucleus |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0006952 | biological_process | defense response |
| T | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| T | 0010427 | molecular_function | abscisic acid binding |
| T | 0038023 | molecular_function | signaling receptor activity |
| U | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| U | 0005634 | cellular_component | nucleus |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0006952 | biological_process | defense response |
| U | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| U | 0010427 | molecular_function | abscisic acid binding |
| U | 0038023 | molecular_function | signaling receptor activity |
| V | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| V | 0005634 | cellular_component | nucleus |
| V | 0005737 | cellular_component | cytoplasm |
| V | 0006952 | biological_process | defense response |
| V | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| V | 0010427 | molecular_function | abscisic acid binding |
| V | 0038023 | molecular_function | signaling receptor activity |
| W | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| W | 0005634 | cellular_component | nucleus |
| W | 0005737 | cellular_component | cytoplasm |
| W | 0006952 | biological_process | defense response |
| W | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| W | 0010427 | molecular_function | abscisic acid binding |
| W | 0038023 | molecular_function | signaling receptor activity |
| X | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| X | 0005634 | cellular_component | nucleus |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0006952 | biological_process | defense response |
| X | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| X | 0010427 | molecular_function | abscisic acid binding |
| X | 0038023 | molecular_function | signaling receptor activity |
| Y | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| Y | 0005634 | cellular_component | nucleus |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0006952 | biological_process | defense response |
| Y | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| Y | 0010427 | molecular_function | abscisic acid binding |
| Y | 0038023 | molecular_function | signaling receptor activity |
| Z | 0004864 | molecular_function | protein phosphatase inhibitor activity |
| Z | 0005634 | cellular_component | nucleus |
| Z | 0005737 | cellular_component | cytoplasm |
| Z | 0006952 | biological_process | defense response |
| Z | 0009738 | biological_process | abscisic acid-activated signaling pathway |
| Z | 0010427 | molecular_function | abscisic acid binding |
| Z | 0038023 | molecular_function | signaling receptor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN A 201 |
| Chain | Residue |
| A | VAL30 |
| A | LYS33 |
| A | ALA34 |
| A | TYR150 |
| A | VAL157 |
| A | PHE158 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2AN A 202 |
| Chain | Residue |
| A | PHE39 |
| A | ILE135 |
| A | GLY136 |
| A | LYS139 |
| A | ALA140 |
| A | HOH303 |
| A | HOH305 |
| A | ARG27 |
| A | LEU31 |
| A | GLN35 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN A 203 |
| Chain | Residue |
| A | GLU10 |
| A | LEU23 |
| A | TYR84 |
| A | GLY114 |
| A | ILE116 |
| A | ALA140 |
| A | TYR144 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN A 204 |
| Chain | Residue |
| A | VAL38 |
| A | HIS63 |
| A | LYS139 |
| M | LYS138 |
| M | TYR141 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN B 201 |
| Chain | Residue |
| B | ARG27 |
| B | LEU31 |
| B | GLN35 |
| B | PHE39 |
| B | PHE59 |
| B | TYR101 |
| B | GLU132 |
| B | ALA140 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN B 202 |
| Chain | Residue |
| B | LYS8 |
| B | GLU10 |
| B | SER12 |
| B | LEU19 |
| B | LEU23 |
| B | VAL103 |
| B | ILE116 |
| B | TYR141 |
| B | TYR144 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN B 203 |
| Chain | Residue |
| B | HIS17 |
| B | ALA77 |
| B | PHE158 |
| Z | GLY109 |
| Z | GLY110 |
| b | GLU46 |
| b | GLY47 |
| b | ASP48 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN B 204 |
| Chain | Residue |
| B | GLU46 |
| B | GLY47 |
| B | ASP48 |
| B | GLY52 |
| N | GLY110 |
| b | LYS21 |
| b | ALA77 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 2AN B 205 |
| Chain | Residue |
| B | VAL30 |
| B | LYS33 |
| B | TYR150 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN C 201 |
| Chain | Residue |
| C | ARG27 |
| C | LEU31 |
| C | GLN35 |
| C | PHE39 |
| C | VAL91 |
| C | TYR101 |
| C | GLY136 |
| C | LYS139 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN C 202 |
| Chain | Residue |
| C | LYS8 |
| C | GLU10 |
| C | LEU19 |
| C | LEU23 |
| C | TYR144 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN C 203 |
| Chain | Residue |
| C | VAL30 |
| C | LYS33 |
| C | VAL147 |
| C | TYR150 |
| C | VAL157 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 2AN C 204 |
| Chain | Residue |
| C | LYS138 |
| K | VAL38 |
| K | LYS138 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE C 205 |
| Chain | Residue |
| C | ILE135 |
| C | LYS138 |
| K | LYS138 |
| K | TYR141 |
| K | GLU142 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN D 201 |
| Chain | Residue |
| D | ARG27 |
| D | LEU31 |
| D | PHE39 |
| D | TYR101 |
| D | LYS139 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2AN D 202 |
| Chain | Residue |
| D | LEU105 |
| D | ILE116 |
| D | ALA140 |
| D | TYR141 |
| D | TYR144 |
| D | LYS8 |
| D | GLU10 |
| D | LEU19 |
| D | LEU23 |
| D | VAL103 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 2AN D 203 |
| Chain | Residue |
| D | LYS138 |
| Q | ARG93 |
| Q | LYS138 |
| site_id | BC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN E 201 |
| Chain | Residue |
| E | ARG27 |
| E | LEU31 |
| E | GLN35 |
| E | PHE39 |
| E | GLY136 |
| E | LYS139 |
| E | ALA140 |
| E | 2AN204 |
| E | HOH301 |
| site_id | CC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN E 202 |
| Chain | Residue |
| E | LYS8 |
| E | SER12 |
| E | LEU23 |
| E | VAL103 |
| E | GLY114 |
| E | ILE116 |
| E | TYR141 |
| E | TYR144 |
| site_id | CC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN E 203 |
| Chain | Residue |
| E | ALA22 |
| E | VAL30 |
| E | LYS33 |
| E | VAL147 |
| E | TYR150 |
| E | LEU151 |
| E | VAL157 |
| E | PHE158 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN E 204 |
| Chain | Residue |
| E | HIS63 |
| E | PRO64 |
| E | LEU65 |
| E | VAL91 |
| E | ARG93 |
| E | 2AN201 |
| E | 2AN205 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN E 205 |
| Chain | Residue |
| E | HIS63 |
| E | ILE135 |
| E | LYS138 |
| E | LYS139 |
| E | 2AN204 |
| I | LYS138 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN F 201 |
| Chain | Residue |
| F | GLU10 |
| F | LEU19 |
| F | LEU23 |
| F | TYR84 |
| F | LEU105 |
| F | ALA140 |
| F | TYR141 |
| F | TYR144 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN G 201 |
| Chain | Residue |
| G | ARG27 |
| G | LEU31 |
| G | PHE39 |
| G | MET68 |
| G | VAL91 |
| G | GLU132 |
| G | LYS139 |
| site_id | CC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN G 202 |
| Chain | Residue |
| G | LYS8 |
| G | GLU10 |
| G | LEU19 |
| G | LEU23 |
| G | TYR84 |
| G | VAL103 |
| G | LEU105 |
| G | ALA140 |
| G | TYR144 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2AN G 203 |
| Chain | Residue |
| G | VAL30 |
| G | LYS33 |
| G | TYR150 |
| G | PHE158 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN G 204 |
| Chain | Residue |
| G | HIS63 |
| G | LYS138 |
| G | LYS139 |
| G | GLU142 |
| G | 2AN205 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2AN G 205 |
| Chain | Residue |
| G | GLU131 |
| G | LYS134 |
| G | ILE135 |
| G | 2AN204 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN H 201 |
| Chain | Residue |
| H | VAL30 |
| H | LYS33 |
| H | TYR150 |
| H | VAL157 |
| H | PHE158 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN H 202 |
| Chain | Residue |
| H | ARG27 |
| H | LEU31 |
| H | PHE39 |
| H | TYR101 |
| H | GLY136 |
| H | LYS139 |
| H | ALA140 |
| site_id | DC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN H 203 |
| Chain | Residue |
| H | LYS8 |
| H | LEU19 |
| H | LEU23 |
| H | VAL103 |
| H | LEU105 |
| H | ILE116 |
| H | ALA140 |
| H | TYR141 |
| H | TYR144 |
| site_id | DC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN I 201 |
| Chain | Residue |
| I | LYS8 |
| I | GLU10 |
| I | SER12 |
| I | LEU19 |
| I | VAL103 |
| I | ILE116 |
| I | TYR144 |
| site_id | DC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN I 202 |
| Chain | Residue |
| I | ARG27 |
| I | LEU31 |
| I | GLN35 |
| I | PHE39 |
| I | MET68 |
| I | GLY136 |
| I | LYS139 |
| I | 2AN205 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN I 203 |
| Chain | Residue |
| I | VAL30 |
| I | LYS33 |
| I | VAL147 |
| I | TYR150 |
| I | VAL157 |
| I | PHE158 |
| site_id | DC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN I 204 |
| Chain | Residue |
| E | LYS138 |
| E | TYR141 |
| I | HIS63 |
| I | LYS139 |
| I | 2AN205 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN I 205 |
| Chain | Residue |
| I | HIS63 |
| I | PRO64 |
| I | LEU65 |
| I | ARG93 |
| I | 2AN202 |
| I | 2AN204 |
| site_id | EC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN J 201 |
| Chain | Residue |
| J | ARG27 |
| J | GLN35 |
| J | PHE39 |
| J | LEU86 |
| J | VAL91 |
| J | TYR101 |
| J | GLY136 |
| J | LYS139 |
| site_id | EC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN J 202 |
| Chain | Residue |
| J | LYS8 |
| J | GLU10 |
| J | LEU19 |
| J | TYR84 |
| J | VAL103 |
| J | ILE116 |
| J | ALA140 |
| J | TYR141 |
| J | TYR144 |
| site_id | EC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN K 201 |
| Chain | Residue |
| K | ARG27 |
| K | LEU31 |
| K | PHE39 |
| K | PHE59 |
| K | MET68 |
| K | LEU86 |
| K | VAL91 |
| K | GLU132 |
| K | GLY136 |
| site_id | EC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN K 202 |
| Chain | Residue |
| K | GLU10 |
| K | LEU19 |
| K | LEU23 |
| K | ARG27 |
| K | TYR84 |
| K | VAL103 |
| K | LEU105 |
| K | ILE116 |
| K | TYR144 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN K 203 |
| Chain | Residue |
| K | VAL30 |
| K | LYS33 |
| K | TYR150 |
| K | VAL157 |
| K | PHE158 |
| site_id | EC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN L 201 |
| Chain | Residue |
| L | ARG27 |
| L | LEU31 |
| L | PHE39 |
| L | LEU86 |
| L | TYR101 |
| L | GLU132 |
| L | GLY136 |
| L | LYS139 |
| site_id | EC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN L 202 |
| Chain | Residue |
| L | LYS8 |
| L | LEU19 |
| L | VAL103 |
| L | ILE116 |
| L | ALA140 |
| L | TYR141 |
| L | TYR144 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN L 203 |
| Chain | Residue |
| L | VAL30 |
| L | LYS33 |
| L | ALA34 |
| L | TYR150 |
| L | VAL157 |
| L | PHE158 |
| site_id | EC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN L 204 |
| Chain | Residue |
| J | GLY110 |
| L | GLU46 |
| L | GLY47 |
| L | ASP48 |
| R | HIS17 |
| R | LYS21 |
| R | ALA77 |
| site_id | FC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN L 205 |
| Chain | Residue |
| L | HIS17 |
| L | ALA77 |
| L | ALA78 |
| L | PHE158 |
| P | GLY109 |
| P | GLY110 |
| R | GLU46 |
| R | GLY47 |
| site_id | FC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN M 201 |
| Chain | Residue |
| M | ARG27 |
| M | LEU31 |
| M | GLN35 |
| M | PHE39 |
| M | PHE59 |
| M | VAL91 |
| M | LYS139 |
| M | ALA140 |
| site_id | FC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN M 202 |
| Chain | Residue |
| M | LYS8 |
| M | GLU10 |
| M | SER12 |
| M | LEU19 |
| M | LEU23 |
| M | VAL103 |
| M | GLY114 |
| M | ILE116 |
| M | TYR144 |
| site_id | FC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN M 203 |
| Chain | Residue |
| M | ALA22 |
| M | VAL30 |
| M | LYS33 |
| M | ALA34 |
| M | VAL147 |
| M | TYR150 |
| M | LEU151 |
| M | VAL157 |
| M | PHE158 |
| site_id | FC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN N 201 |
| Chain | Residue |
| N | ARG27 |
| N | LEU31 |
| N | GLN35 |
| N | PHE39 |
| N | PHE59 |
| N | MET68 |
| N | GLU132 |
| N | GLY136 |
| site_id | FC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN N 202 |
| Chain | Residue |
| N | LYS8 |
| N | GLU10 |
| N | LEU19 |
| N | LEU23 |
| N | VAL103 |
| N | ILE116 |
| N | ALA140 |
| N | TYR141 |
| N | TYR144 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN N 203 |
| Chain | Residue |
| N | LYS138 |
| N | TYR141 |
| N | 2AN204 |
| a | VAL38 |
| a | HIS63 |
| a | LYS139 |
| site_id | FC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN N 204 |
| Chain | Residue |
| N | TYR141 |
| N | 2AN203 |
| a | HIS37 |
| a | VAL60 |
| a | GLY62 |
| a | HIS63 |
| a | PRO64 |
| site_id | FC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN O 201 |
| Chain | Residue |
| O | LYS8 |
| O | GLU10 |
| O | LEU19 |
| O | LEU23 |
| O | TYR84 |
| O | ILE116 |
| O | ALA140 |
| O | TYR144 |
| site_id | GC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN O 202 |
| Chain | Residue |
| O | ARG27 |
| O | LEU31 |
| O | GLN35 |
| O | PHE39 |
| O | PHE59 |
| O | TYR101 |
| O | GLY136 |
| O | LYS139 |
| O | ALA140 |
| site_id | GC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN P 201 |
| Chain | Residue |
| P | ARG27 |
| P | LEU31 |
| P | GLN35 |
| P | PHE39 |
| P | VAL91 |
| P | TYR101 |
| P | LYS139 |
| site_id | GC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN P 202 |
| Chain | Residue |
| P | VAL30 |
| P | LYS33 |
| P | ALA34 |
| P | VAL147 |
| P | TYR150 |
| P | LEU151 |
| P | VAL157 |
| P | PHE158 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN Q 201 |
| Chain | Residue |
| Q | GLU10 |
| Q | LEU19 |
| Q | LEU23 |
| Q | ILE116 |
| Q | TYR141 |
| Q | TYR144 |
| site_id | GC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN Q 202 |
| Chain | Residue |
| I | GLY47 |
| K | GLY109 |
| K | GLY110 |
| Q | HIS17 |
| Q | LYS21 |
| Q | ALA77 |
| site_id | GC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN Q 203 |
| Chain | Residue |
| I | ALA77 |
| Q | GLU46 |
| Q | GLY47 |
| S | GLY109 |
| S | GLY110 |
| site_id | GC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2AN R 201 |
| Chain | Residue |
| R | LYS8 |
| R | GLU10 |
| R | GLU11 |
| R | LEU23 |
| R | ARG27 |
| R | TYR84 |
| R | VAL103 |
| R | ILE116 |
| R | ALA140 |
| R | TYR144 |
| site_id | GC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN R 202 |
| Chain | Residue |
| R | ARG27 |
| R | LEU31 |
| R | GLN35 |
| R | PHE39 |
| R | PHE59 |
| R | VAL91 |
| R | TYR101 |
| R | LYS139 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2AN R 203 |
| Chain | Residue |
| R | VAL30 |
| R | LYS33 |
| R | TYR150 |
| R | VAL157 |
| R | PHE158 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2AN R 204 |
| Chain | Residue |
| R | LYS145 |
| X | HIS63 |
| X | PRO64 |
| X | LYS139 |
| site_id | HC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN S 201 |
| Chain | Residue |
| S | ARG27 |
| S | LEU31 |
| S | GLN35 |
| S | GLU132 |
| S | ILE135 |
| S | GLY136 |
| S | ALA140 |
| S | PHE143 |
| site_id | HC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2AN U 201 |
| Chain | Residue |
| U | LYS8 |
| U | LEU19 |
| U | LEU23 |
| U | ARG27 |
| U | VAL103 |
| U | LEU105 |
| U | ILE116 |
| U | ALA140 |
| U | TYR141 |
| U | TYR144 |
| site_id | HC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN U 202 |
| Chain | Residue |
| U | ARG27 |
| U | LEU31 |
| U | GLN35 |
| U | PHE39 |
| U | GLY136 |
| U | LYS139 |
| U | ALA140 |
| site_id | HC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2AN U 203 |
| Chain | Residue |
| E | ALA77 |
| U | GLU46 |
| U | GLY47 |
| W | GLY110 |
| site_id | HC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN U 204 |
| Chain | Residue |
| E | GLY47 |
| E | ASP48 |
| G | GLY109 |
| G | GLY110 |
| U | HIS17 |
| U | LYS21 |
| U | ALA77 |
| U | PHE158 |
| site_id | HC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE 2AN U 205 |
| Chain | Residue |
| U | ILE135 |
| U | LYS138 |
| site_id | HC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN V 201 |
| Chain | Residue |
| T | HIS37 |
| T | GLY62 |
| T | HIS63 |
| T | PRO64 |
| V | LYS138 |
| V | TYR141 |
| V | GLU142 |
| V | LYS145 |
| site_id | HC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN V 202 |
| Chain | Residue |
| T | GLU142 |
| T | LYS145 |
| V | HIS37 |
| V | VAL38 |
| V | HIS63 |
| V | PRO64 |
| site_id | IC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 V 203 |
| Chain | Residue |
| V | ARG27 |
| V | LEU31 |
| V | MET68 |
| site_id | IC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN W 201 |
| Chain | Residue |
| J | TYR141 |
| J | LYS145 |
| W | HIS37 |
| W | GLY62 |
| W | HIS63 |
| W | PRO64 |
| W | 2AN204 |
| site_id | IC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN W 202 |
| Chain | Residue |
| W | LYS8 |
| W | GLU10 |
| W | LEU19 |
| W | LEU23 |
| W | VAL103 |
| W | ILE116 |
| W | ALA140 |
| W | TYR144 |
| site_id | IC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN W 203 |
| Chain | Residue |
| W | ARG27 |
| W | LEU31 |
| W | GLN35 |
| W | PHE39 |
| W | PHE59 |
| W | ILE135 |
| W | GLY136 |
| W | ALA140 |
| site_id | IC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN W 204 |
| Chain | Residue |
| J | LYS138 |
| J | TYR141 |
| W | VAL38 |
| W | HIS63 |
| W | LYS138 |
| W | LYS139 |
| W | 2AN201 |
| site_id | IC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN X 201 |
| Chain | Residue |
| X | ARG27 |
| X | LEU31 |
| X | GLN35 |
| X | PHE39 |
| X | PHE59 |
| X | LEU65 |
| X | MET68 |
| X | VAL91 |
| X | LYS139 |
| site_id | IC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN X 202 |
| Chain | Residue |
| X | LYS8 |
| X | GLU10 |
| X | LEU23 |
| X | ARG27 |
| X | TYR84 |
| X | ILE116 |
| X | TYR144 |
| site_id | IC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN X 203 |
| Chain | Residue |
| R | HIS37 |
| R | HIS63 |
| R | PRO64 |
| X | TYR141 |
| X | GLU142 |
| X | LYS145 |
| site_id | IC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 X 204 |
| Chain | Residue |
| R | LYS138 |
| R | LYS139 |
| X | LYS138 |
| X | GLU142 |
| site_id | JC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN Y 201 |
| Chain | Residue |
| Y | ARG27 |
| Y | LEU31 |
| Y | GLN35 |
| Y | PHE39 |
| Y | TYR101 |
| Y | GLY136 |
| Y | LYS139 |
| site_id | JC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN Y 202 |
| Chain | Residue |
| Y | LYS8 |
| Y | GLU10 |
| Y | LEU19 |
| Y | LEU23 |
| Y | VAL103 |
| Y | LEU105 |
| Y | ILE116 |
| Y | ALA140 |
| Y | TYR144 |
| site_id | JC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN Y 203 |
| Chain | Residue |
| A | HIS17 |
| A | LYS21 |
| A | LEU25 |
| A | ALA77 |
| Y | GLY47 |
| Y | HOH301 |
| a | GLY109 |
| a | GLY110 |
| site_id | JC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2AN Y 204 |
| Chain | Residue |
| A | GLY47 |
| A | ASP48 |
| C | GLY109 |
| Y | HIS17 |
| Y | LYS21 |
| Y | ALA77 |
| Y | PHE158 |
| site_id | JC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN Z 201 |
| Chain | Residue |
| Z | ARG27 |
| Z | GLN35 |
| Z | PHE39 |
| Z | MET68 |
| Z | VAL91 |
| Z | TYR101 |
| Z | GLY136 |
| Z | LYS139 |
| Z | HOH303 |
| site_id | JC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN Z 202 |
| Chain | Residue |
| Z | LYS8 |
| Z | GLU10 |
| Z | LEU19 |
| Z | ARG27 |
| Z | LEU105 |
| Z | ILE116 |
| Z | ALA140 |
| Z | TYR141 |
| Z | TYR144 |
| site_id | JC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 2AN Z 203 |
| Chain | Residue |
| Z | VAL30 |
| Z | LYS33 |
| Z | TYR150 |
| Z | VAL157 |
| site_id | JC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EPE Z 204 |
| Chain | Residue |
| P | LYS138 |
| P | TYR141 |
| Z | LYS139 |
| site_id | JC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2AN a 201 |
| Chain | Residue |
| a | LYS8 |
| a | GLU10 |
| a | LEU19 |
| a | LEU23 |
| a | ARG27 |
| a | TYR84 |
| a | VAL103 |
| a | ILE116 |
| a | TYR144 |
| site_id | KC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN b 201 |
| Chain | Residue |
| b | LYS8 |
| b | GLU10 |
| b | GLU11 |
| b | LEU23 |
| b | ARG27 |
| b | TYR84 |
| b | ILE116 |
| b | TYR144 |
| site_id | KC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2AN b 202 |
| Chain | Residue |
| b | ARG27 |
| b | GLN35 |
| b | PHE39 |
| b | LEU65 |
| b | MET68 |
| b | VAL91 |
| b | TYR101 |
| b | LYS139 |
| site_id | KC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2AN b 203 |
| Chain | Residue |
| b | HIS37 |
| b | HIS63 |
| b | PRO64 |
| b | TYR141 |
| b | GLU142 |
| b | SO4204 |
| site_id | KC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 b 204 |
| Chain | Residue |
| b | LYS138 |
| b | LYS138 |
| b | LYS139 |
| b | 2AN203 |
Functional Information from PROSITE/UniProt
| site_id | PS00451 |
| Number of Residues | 32 |
| Details | PATHOGENESIS_BETVI Pathogenesis-related proteins Bet v I family signature. GdvLrdniEkv.Vyevkleav.GGGSkgKitvtY |
| Chain | Residue | Details |
| A | GLY89-TYR120 |
