8H9D
Crystal structure of Cas12a protein
Summary for 8H9D
Entry DOI | 10.2210/pdb8h9d/pdb |
Descriptor | Cas12A, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3'), SULFATE ION, ... (6 entities in total) |
Functional Keywords | crispr-cas, cas12a, dna binding protein |
Biological source | Lachnospiraceae bacterium More |
Total number of polymer chains | 3 |
Total formula weight | 289319.01 |
Authors | Jianwei, L.,Jobichen, C.,Sivaraman, J. (deposition date: 2022-10-25, release date: 2023-02-08, Last modification date: 2023-11-29) |
Primary citation | Jianwei, L.,Jobichen, C.,Machida, S.,Meng, S.,Read, R.J.,Hongying, C.,Jian, S.,Yuan, Y.A.,Sivaraman, J. Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage. Plos Biol., 21:e3002023-e3002023, 2023 Cited by PubMed: 36917574DOI: 10.1371/journal.pbio.3002023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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