8H9D

Crystal structure of Cas12a protein

Summary for 8H9D

• Entry DOI: 10.2210/pdb8h9d/pdb
• Descriptor: Cas12A, RNA (5'-R(P*AP*AP*UP*UP*UP*CP*UP*AP*CP*UP*AP*AP*GP*UP*GP*UP*AP*GP*AP*UP*C)-3'), SULFATE ION, ... (6 entities in total)
• Functional Keywords: crispr-cas, cas12a, dna binding protein
• Biological source: Lachnospiraceae bacterium; More
• Total number of polymer chains: 3
• Total formula weight: 289319.01

Authors

Jianwei, L.,Jobichen, C.,Sivaraman, J. (deposition date: 2022-10-25, release date: 2023-02-08, Last modification date: 2023-11-29)

• Primary citation: Jianwei, L.,Jobichen, C.,Machida, S.,Meng, S.,Read, R.J.,Hongying, C.,Jian, S.,Yuan, Y.A.,Sivaraman, J.; Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.; Plos Biol., 21:e3002023-e3002023, 2023; PubMed: 36917574; DOI: 10.1371/journal.pbio.3002023

Experimental method

X-RAY DIFFRACTION (3.1 Å)