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1TRS
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BU of 1trs by Molmil
THE HIGH-RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURES OF THE OXIDIZED AND REDUCED STATES OF HUMAN THIOREDOXIN
Descriptor: THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1994-05-10
Release date:1994-09-30
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The high-resolution three-dimensional solution structures of the oxidized and reduced states of human thioredoxin.
Structure, 2, 1994
1MDI
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BU of 1mdi by Molmil
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB
Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDK
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BU of 1mdk by Molmil
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
1MDJ
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BU of 1mdj by Molmil
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB (RESIDUES 56-68 OF THE P50 SUBUNIT OF NFKB)
Descriptor: TARGET SITE IN HUMAN NFKB, THIOREDOXIN
Authors:Clore, G.M, Qin, J, Gronenborn, A.M.
Deposit date:1995-02-27
Release date:1995-06-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B.
Structure, 3, 1995
5EJC
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BU of 5ejc by Molmil
Crystal structural of the TSC1-TBC1D7 complex
Descriptor: Hamartin, TBC1 domain family member 7
Authors:Wang, Z, Qin, J, Gong, W, Xu, W.
Deposit date:2015-11-01
Release date:2016-03-02
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
3REP
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BU of 3rep by Molmil
Crystal structure of the ILK/alpha-parvin core complex (MnATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ...
Authors:Fukuda, K, Qin, J.
Deposit date:2011-04-04
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the ILK/alpha-parvin core complex (MnATP)
To be Published
2KNC
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BU of 2knc by Molmil
Platelet integrin ALFAIIB-BETA3 transmembrane-cytoplasmic heterocomplex
Descriptor: Integrin alpha-IIb, Integrin beta-3
Authors:Yang, J, Ma, Y, Page, R.C, Misra, S, Plow, E.F, Qin, J.
Deposit date:2009-08-20
Release date:2009-09-29
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structure of an integrin alphaIIb beta3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation.
Proc.Natl.Acad.Sci.USA, 106, 2009
3KMW
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BU of 3kmw by Molmil
Crystal structure of the ILK/alpha-parvin core complex (MgATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-parvin, Integrin-linked kinase, ...
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
3KMU
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BU of 3kmu by Molmil
Crystal structure of the ILK/alpha-parvin core complex (apo)
Descriptor: Alpha-parvin, Integrin-linked kinase
Authors:Fukuda, K, Qin, J.
Deposit date:2009-11-11
Release date:2009-12-29
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
Mol.Cell, 36, 2009
2K9U
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BU of 2k9u by Molmil
Solution NMR structure of the Filamin-migfilin complex
Descriptor: Filamin-binding LIM protein 1, Gamma filamin
Authors:Ithychanda, S.N, Qin, J.
Deposit date:2008-10-24
Release date:2008-12-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Migfilin, a molecular switch in regulation of integrin activation.
J.Biol.Chem., 284, 2009
7SC4
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BU of 7sc4 by Molmil
filamin complex-1
Descriptor: Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION
Authors:Liu, J, Qin, J.
Deposit date:2021-09-27
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
7SFT
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BU of 7sft by Molmil
Filamin complex-2
Descriptor: Filamin-A, Integrin alpha-IIb light chain, form 2
Authors:Liu, J, Qin, J.
Deposit date:2021-10-04
Release date:2023-04-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
6U4M
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BU of 6u4m by Molmil
Solution structure of paxillin LIM4
Descriptor: Paxillin, ZINC ION
Authors:Zhu, L, Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
5J2Y
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BU of 5j2y by Molmil
Molecular insight into the regulatory mechanism of the quorum-sensing repressor RsaL in Pseudomonas aeruginosa
Descriptor: DNA (26-MER), Regulatory protein
Authors:Zhao, J, Gan, J, Zhang, J, Kang, H, Kong, W, Zhu, M, Li, F, Song, Y, Qin, J, Liang, H.
Deposit date:2016-03-30
Release date:2017-04-12
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Pseudomonas aeruginosa RsaL bound to promoter DNA reaffirms its role as a global regulator involved in quorum-sensing.
Nucleic Acids Res., 45, 2017
3ISW
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BU of 3isw by Molmil
Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR
Descriptor: Cystic fibrosis transmembrane conductance regulator, Filamin-A
Authors:Xu, Z, Page, R, Qin, J, Ithychanda, S.S, Liu, J.M, Misra, S.
Deposit date:2009-08-27
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
J.Biol.Chem., 285, 2010
6U4N
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BU of 6u4n by Molmil
Solution structure of paxillin LIM4 in complex with kindlin-2 F0
Descriptor: Fermitin family homolog 2, Paxillin, ZINC ION
Authors:Zhu, L, Qin, J.
Deposit date:2019-08-26
Release date:2019-10-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion.
Structure, 27, 2019
3CWG
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BU of 3cwg by Molmil
Unphosphorylated mouse STAT3 core fragment
Descriptor: Signal transducer and activator of transcription 3
Authors:Ren, Z, Mao, X, Mertens, C, Krishnaraj, R, Qin, J, Mandal, P.K, Romanowshi, M.J, McMurray, J.S.
Deposit date:2008-04-21
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of unphosphorylated STAT3 core fragment.
Biochem.Biophys.Res.Commun., 374, 2008
4F7G
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BU of 4f7g by Molmil
Crystal structure of talin autoinhibition complex
Descriptor: Talin-1
Authors:Song, X, Qin, J, Ye, S, Zhang, R.
Deposit date:2012-05-16
Release date:2012-07-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
Cell Res., 22, 2012
2LGX
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BU of 2lgx by Molmil
NMR structure for Kindle-2 N-terminus
Descriptor: Fermitin family homolog 2
Authors:Perera, H.D, Ma, Y, Yang, J, Hirbawi, J, Plow, E.F, Qin, J.
Deposit date:2011-08-03
Release date:2011-11-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation.
Structure, 19, 2011
2MYO
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BU of 2myo by Molmil
SOLUTION STRUCTURE OF MYOTROPHIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: MYOTROPHIN
Authors:Yang, Y, Nanduri, S, Sen, S, Qin, J.
Deposit date:1998-08-17
Release date:1999-08-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin.
Structure, 6, 1998
1MYO
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BU of 1myo by Molmil
SOLUTION STRUCTURE OF MYOTROPHIN, NMR, 44 STRUCTURES
Descriptor: MYOTROPHIN
Authors:Yang, Y, Nanduri, S, Sen, S, Qin, J.
Deposit date:1998-08-17
Release date:1999-08-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin.
Structure, 6, 1998
2MWN
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BU of 2mwn by Molmil
Talin-F3 / RIAM N-terminal Peptide complex
Descriptor: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1
Authors:Yang, J, Zhu, L, Zhang, H, Hirbawi, J, Fukuda, K, Dwivedi, P, Liu, J, Byzova, T, Plow, E.F, Wu, J, Qin, J.
Deposit date:2014-11-13
Release date:2014-12-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
Nat Commun, 5, 2014
8G59
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BU of 8g59 by Molmil
Cryo-EM structure of the TUG891 bound GPR120-Giq complex
Descriptor: 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Mao, C, Xiao, P, Tao, X, Qin, J, He, Q, Zhang, C, Yu, X, Zhang, Y, Sun, J.
Deposit date:2023-02-12
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Science, 380, 2023
1U5S
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BU of 1u5s by Molmil
NMR structure of the complex between Nck-2 SH3 domain and PINCH-1 LIM4 domain
Descriptor: Cytoplasmic protein NCK2, PINCH protein, ZINC ION
Authors:Vaynberg, J, Fukuda, T, Vinogradova, O, Velyvis, A, Ng, L, Wu, C, Qin, J.
Deposit date:2004-07-28
Release date:2005-04-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of an ultraweak protein-protein complex and its crucial role in regulation of cell morphology and motility.
Mol.Cell, 17, 2005
1S4W
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BU of 1s4w by Molmil
NMR structure of the cytoplasmic domain of integrin AIIb in DPC micelles
Descriptor: Integrin alpha-IIb
Authors:Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J.
Deposit date:2004-01-19
Release date:2004-03-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004

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