1B0X
 
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1BY1
 | | DBL homology domain from beta-PIX | | 分子名称: | PROTEIN (PIX) | | 著者 | Aghazadeh, B, Zhu, K, Kubiseski, T.J, Liu, G.A, Pawson, T, Zheng, Y, Rosen, M.K. | | 登録日 | 1998-10-22 | | 公開日 | 1999-10-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Mutagenesis of the Dbl Homology Domain
Nat.Struct.Biol., 5, 1998
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1Z1V
 | | NMR structure of the Saccharomyces cerevisiae Ste50 SAM domain | | 分子名称: | STE50 protein | | 著者 | Kwan, J.J, Warner, N, Maini, J, Pawson, T, Donaldson, L.W. | | 登録日 | 2005-03-06 | | 公開日 | 2006-02-14 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head-to-tail SAM domain interaction.
J.Mol.Biol., 356, 2006
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1DDM
 | | SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE | | 分子名称: | NUMB ASSOCIATE KINASE, NUMB PROTEIN | | 著者 | Zwahlen, C, Li, S.C, Kay, L.E, Pawson, T, Forman-Kay, J.D. | | 登録日 | 1999-11-11 | | 公開日 | 2000-04-10 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb.
EMBO J., 19, 2000
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1H3H
 | | Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain | | 分子名称: | GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 | | 著者 | Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S. | | 登録日 | 2002-09-03 | | 公開日 | 2003-03-06 | | 最終更新日 | 2013-07-24 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition
Mol.Cell, 11, 2003
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1F1W
 | | SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN | | 分子名称: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE | | 著者 | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | | 登録日 | 2000-05-20 | | 公開日 | 2000-07-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
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1F2F
 | | SRC SH2 THREF1TRP MUTANT | | 分子名称: | PHOSPHATE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | | 著者 | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | | 登録日 | 2000-05-24 | | 公開日 | 2000-07-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for specificity switching of the Src SH2 domain.
Mol.Cell, 5, 2000
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1JU5
 | | Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy | | 分子名称: | Abl, Crk | | 著者 | Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D. | | 登録日 | 2001-08-23 | | 公開日 | 2002-11-06 | | 最終更新日 | 2021-11-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a regulatory complex involving the Abl SH3 domain, the Crk
SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99, 2002
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1JPA
 | | Crystal Structure of unphosphorylated EphB2 receptor tyrosine kinase and juxtamembrane region | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, neural kinase, Nuk=Eph/Elk/Eck family receptor-like tyrosine kinase | | 著者 | Wybenga-Groot, L.E, Pawson, T, Sicheri, F. | | 登録日 | 2001-08-01 | | 公開日 | 2001-10-03 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.
Cell(Cambridge,Mass.), 106, 2001
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1KA7
 | | SAP/SH2D1A bound to peptide n-Y-c | | 分子名称: | SH2 DOMAIN PROTEIN 1A, peptide n-Y-c | | 著者 | Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C. | | 登録日 | 2001-10-31 | | 公開日 | 2001-11-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
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1KA6
 | | SAP/SH2D1A bound to peptide n-pY | | 分子名称: | SH2 DOMAIN PROTEIN 1A, peptide n-pY | | 著者 | Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C. | | 登録日 | 2001-10-31 | | 公開日 | 2001-11-07 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
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2HEN
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2HEL
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2JFA
 | | ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE | | 分子名称: | COREPRESSOR PEPTIDE, ESTROGEN RECEPTOR, RALOXIFENE, ... | | 著者 | Heldring, N, Pawson, T, McDonnell, D, Treuter, E, Gustafsson, J.A, Pike, A.C.W. | | 登録日 | 2007-01-29 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
J.Biol.Chem., 282, 2007
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2JF9
 | | ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST | | 分子名称: | 1,2-ETHANEDIOL, 4-HYDROXYTAMOXIFEN, AB5 PEPTIDE, ... | | 著者 | Heldring, N, Pawson, T, McDonnell, D, Treuter, E, Gustafsson, J.A, Pike, A.C.W. | | 登録日 | 2007-01-29 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
J.Biol.Chem., 282, 2007
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2KIS
 | | Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker | | 分子名称: | Transcription elongation regulator 1 | | 著者 | Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T. | | 登録日 | 2009-05-08 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays.
J.Mol.Biol., 393, 2009
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2NMB
 | | DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES. | | 分子名称: | PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN) | | 著者 | Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D. | | 登録日 | 1998-10-29 | | 公開日 | 1998-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
Nat.Struct.Biol., 5, 1998
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2PLE
 | | NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | | 登録日 | 1994-08-19 | | 公開日 | 1995-01-26 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
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2PLD
 | | NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | | 登録日 | 1994-08-19 | | 公開日 | 1995-01-26 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide.
Cell(Cambridge,Mass.), 77, 1994
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2P0F
 | | ArhGAP9 PH domain in complex with Ins(1,3,5)P3 | | 分子名称: | PHOSPHATE ION, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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2P0H
 | | ArhGAP9 PH domain in complex with Ins(1,3,4)P3 | | 分子名称: | (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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2P0D
 | | ArhGAP9 PH domain in complex with Ins(1,4,5)P3 | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rho GTPase-activating protein 9 | | 著者 | Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F. | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.811 Å) | | 主引用文献 | Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
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2QNJ
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3V7D
 | | Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex | | 分子名称: | Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1 | | 著者 | Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M. | | 登録日 | 2011-12-20 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | | 主引用文献 | Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4LG6
 | | Crystal structure of ANKRA2-CCDC8 complex | | 分子名称: | Ankyrin repeat family A protein 2, Coiled-coil domain-containing protein 8, UNKNOWN ATOM OR ION | | 著者 | Xu, C, Bian, C, Tempel, W, Mackenzie, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-27 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Ankyrin Repeats of ANKRA2 Recognize a PxLPxL Motif on the 3M Syndrome Protein CCDC8.
Structure, 23, 2015
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