2KF8
| Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution | Descriptor: | HUMAN TELOMERE DNA | Authors: | Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T. | Deposit date: | 2009-02-12 | Release date: | 2009-03-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers J.Am.Chem.Soc., 131, 2009
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2KGI
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2KYO
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4LOH
| Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOJ
| Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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2KPR
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2KYP
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6VRB
| Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex | Descriptor: | AcrVIA1, CRISPR-associated endoribonuclease Cas13a, RNA (52-MER) | Authors: | Jia, N, Meeske, A.J, Marraffini, L.A, Patel, D.J. | Deposit date: | 2020-02-07 | Release date: | 2020-06-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity. Science, 369, 2020
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6VRC
| Cryo-EM structure of Cas13(crRNA) | Descriptor: | CRISPR-associated endoribonuclease Cas13a, RNA (51-MER) | Authors: | Jia, N, Meeske, A.J, Marraffini, L.A, Patel, D.J. | Deposit date: | 2020-02-07 | Release date: | 2020-06-10 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity. Science, 369, 2020
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7WRN
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7VKJ
| Structure of ESRP1 qRRM3 domain | Descriptor: | Epithelial splicing regulatory protein 1 | Authors: | Wu, B.X, Patel, D.J. | Deposit date: | 2021-09-30 | Release date: | 2022-10-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of ESRP1 qRRM3 domain To Be Published
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6MUR
| Cryo-EM structure of Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system | Descriptor: | RNA (27-MER), RNA (5'-R(P*GP*CP*AP*AP*AP*CP*CP*GP*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*C)-3'), Uncharacterized protein, ... | Authors: | Jia, N, Wang, C, Eng, E.T, Patel, D.J. | Deposit date: | 2018-10-23 | Release date: | 2018-12-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity. Mol. Cell, 73, 2019
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6MJW
| human cGAS catalytic domain bound with the inhibitor G150 | Descriptor: | 1-[9-(6-aminopyridin-3-yl)-6,7-dichloro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl]-2-hydroxyethan-1-one, Cyclic GMP-AMP synthase, ZINC ION | Authors: | Lama, L, Adura, C, Xie, W, Tomita, D, Kamei, T, Kuryavyi, V, Gogakos, T, Steinberg, J.I, Miller, M, Ramos-Espiritu, L, Asano, Y, Hashizume, S, Aida, J, Imaeda, T, Okamoto, R, Jennings, A.J, Michinom, M, Kuroita, T, Stamford, A, Gao, P, Meinke, P, Glickman, J.F, Patel, D.J, Tuschl, T. | Deposit date: | 2018-09-23 | Release date: | 2019-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.405 Å) | Cite: | Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun, 10, 2019
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6MUT
| Cryo-EM structure of ternary Csm-crRNA-target RNA with anti-tag sequence complex in type III-A CRISPR-Cas system | Descriptor: | RNA (5'-R(*GP*UP*GP*GP*AP*AP*AP*GP*GP*CP*GP*GP*GP*CP*AP*GP*AP*GP*GP*C)-3'), RNA (5'-R(P*CP*CP*UP*CP*UP*GP*CP*CP*CP*GP*CP*CP*UP*UP*UP*CP*CP*AP*C)-3'), Uncharacterized protein Csm1, ... | Authors: | Jia, N, Wang, C, Eng, E.T, Patel, D.J. | Deposit date: | 2018-10-23 | Release date: | 2018-12-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity. Mol. Cell, 73, 2019
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3KHR
| Dpo4 post-extension ternary complex with the correct C opposite the 2-aminofluorene-guanine [AF]G lesion | Descriptor: | 2-AMINOFLUORENE, 5'-D(*CP*C*TP*AP*AP*CP*GP*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*GP*CP*(DDG))-3', ... | Authors: | Rechkoblit, O, Malinina, L, Patel, D.J. | Deposit date: | 2009-10-30 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nat.Struct.Mol.Biol., 17, 2010
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8URU
| Spo11 core complex with hairpin DNA | Descriptor: | Antiviral protein SKI8, Hairpin DNA, MAGNESIUM ION, ... | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-10-26 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structure of the yeast Spo11 core complex bound to DNA To Be Published
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3KV0
| Crystal structure of HET-C2: A FUNGAL GLYCOLIPID TRANSFER PROTEIN (GLTP) | Descriptor: | HET-C2 | Authors: | Simanshu, D.K, Kenoth, R, Brown, R.E, Patel, D.J. | Deposit date: | 2009-11-28 | Release date: | 2010-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J.Biol.Chem., 285, 2010
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3LMA
| Crystal structure of the stage V sporulation protein AD (SpoVAD) from Bacillus licheniformis. Northeast Structural Genomics Consortium Target BiR6. | Descriptor: | Stage V sporulation protein AD (SpoVAD) | Authors: | Vorobiev, S, Ashok, S, Seetharaman, J, Belote, R.L, Ciccosanti, C, Patel, D.J, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-29 | Release date: | 2010-02-09 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.993 Å) | Cite: | Crystal structure of the stage V sporulation protein AD (SpoVAD) from Bacillus licheniformis. To be Published
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3LD7
| Crystal structure of the Lin0431 protein from Listeria innocua, Northeast Structural Genomics Consortium Target LkR112 | Descriptor: | Lin0431 protein | Authors: | Vorobiev, S, Chen, Y, Lee, D, Patel, D.J, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-12 | Release date: | 2010-01-26 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.547 Å) | Cite: | Crystal structure of the Lin0431 protein from Listeria innocua To be Published
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3LPY
| Crystal structure of the RRM domain of CyP33 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Peptidyl-prolyl cis-trans isomerase E, SULFATE ION | Authors: | Wang, Z, Patel, D.J. | Deposit date: | 2010-02-07 | Release date: | 2010-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141, 2010
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3LQH
| Crystal structure of MLL1 PHD3-Bromo in the free form | Descriptor: | Histone-lysine N-methyltransferase MLL, ZINC ION | Authors: | Wang, Z, Patel, D.J. | Deposit date: | 2010-02-09 | Release date: | 2010-07-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell(Cambridge,Mass.), 141, 2010
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3LML
| Crystal Structure of the sheath tail protein Lin1278 from Listeria innocua, Northeast Structural Genomics Consortium Target LkR115 | Descriptor: | Lin1278 protein | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Patel, D.J, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-31 | Release date: | 2010-03-09 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Northeast Structural Genomics Consortium Target LkR115 To be Published
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3LQJ
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3LQI
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8URQ
| Spo11 core complex with gapped DNA | Descriptor: | Antiviral protein SKI8, MAGNESIUM ION, Meiosis-specific protein SPO11, ... | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-10-26 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the yeast Spo11 core complex bound to DNA To Be Published
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