6VRB

Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex

Summary for 6VRB

• Entry DOI: 10.2210/pdb6vrb/pdb
• EMDB information: 21366
• Descriptor: RNA (52-MER), CRISPR-associated endoribonuclease Cas13a, AcrVIA1 (3 entities in total)
• Functional Keywords: crispr-cas system, cas13, type via, immune system, anti-crispr, hydrolase, rna
• Biological source: Listeria seeligeri serovar 1/2b (strain ATCC 35967 / DSM 20751 / CIP 100100 / SLCC 3954); More
• Total number of polymer chains: 3
• Total formula weight: 172030.14

Authors

Jia, N.,Meeske, A.J.,Marraffini, L.A.,Patel, D.J. (deposition date: 2020-02-07, release date: 2020-06-10, Last modification date: 2024-03-06)

• Primary citation: Meeske, A.J.,Jia, N.,Cassel, A.K.,Kozlova, A.,Liao, J.,Wiedmann, M.,Patel, D.J.,Marraffini, L.A.; A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity.; Science, 369:54-59, 2020; PubMed: 32467331; DOI: 10.1126/science.abb6151

Experimental method

ELECTRON MICROSCOPY (3 Å)