6E6T
| Dieckmann cyclase, NcmC, bound to cerulenin | Descriptor: | (4S,5R)-4,5-dihydroxy-5-[(3E,6E)-octa-3,6-dien-1-yl]pyrrolidin-2-one, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
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6E6U
| Variant C89S of Dieckmann cyclase, NcmC | Descriptor: | Dieckmann cyclase, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
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6EC8
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1OKN
| CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKN INHIBITOR 4-SULFONAMIDE-[1-(4-N-(5-FLUORESCEIN THIOUREA)BUTANE)] | Descriptor: | 4-SULFONAMIDE-[4-(THIOMETHYLAMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | Authors: | Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. | Deposit date: | 1996-06-25 | Release date: | 1997-01-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
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1OKM
| CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE | Descriptor: | 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | Authors: | Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. | Deposit date: | 1996-06-25 | Release date: | 1997-01-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
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6E6Y
| Dieckmann cyclase, NcmC | Descriptor: | Dieckmann cyclase, NcmC, SULFATE ION | Authors: | Cogan, D.P, Nair, S.K. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Basis for Enzymatic Off-Loading of Hybrid Polyketides by Dieckmann Condensation. Acs Chem.Biol., 2020
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6EC7
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2A9I
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7MSK
| ThuS glycosin S-glycosyltransferase | Descriptor: | Glyco_trans_2-like domain-containing protein, MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | Authors: | Garg, N, Nair, S.K. | Deposit date: | 2021-05-11 | Release date: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural and mechanistic investigations of protein S-glycosyltransferases. Cell Chem Biol, 28, 2021
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7MSN
| SunS glycosin S-glycosyltransferase | Descriptor: | SPbeta prophage-derived glycosyltransferase SunS, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Garg, N, Nair, S.K. | Deposit date: | 2021-05-11 | Release date: | 2022-04-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and mechanistic investigations of protein S-glycosyltransferases. Cell Chem Biol, 28, 2021
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7MSP
| SunS glycosin S-glycosyltransferase | Descriptor: | MAGNESIUM ION, SPbeta prophage-derived glycosyltransferase SunS, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Garg, N, Nair, S.K. | Deposit date: | 2021-05-11 | Release date: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and mechanistic investigations of protein S-glycosyltransferases. Cell Chem Biol, 28, 2021
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8F72
| Phage P32 gp64- RNA polymerase | Descriptor: | MAGNESIUM ION, TPR_REGION domain-containing protein | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2022-11-17 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Thermophage RNA polymerase To Be Published
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8F5M
| Crystal structure of P74 gp62 | Descriptor: | Envelope glycoprotein gp62, MAGNESIUM ION | Authors: | Bae, B, Nair, S.K. | Deposit date: | 2022-11-14 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail. Nat Commun, 15, 2024
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8FTS
| SgvM methyltransferase with SAH and alpha-ketoleucine | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Kuzelka, K, Nair, S.K. | Deposit date: | 2023-01-13 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases Nat Commun, 14, 2023
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8FTV
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8FTR
| SgvM methyltransferase with MTA and alpha-ketoleucine | Descriptor: | 2-OXO-4-METHYLPENTANOIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methyltransferase, ... | Authors: | Kuzelka, K, Nair, S.K. | Deposit date: | 2023-01-13 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases. Nat Commun, 14, 2023
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4ETX
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4EUV
| Crystal Structure of PelD 158-CT from Pseudomonas aeruginosa PAO1, in complex with c-di-GMP, form 1 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), PelD | Authors: | Li, Z, Chen, J, Nair, S.K. | Deposit date: | 2012-04-25 | Release date: | 2012-07-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the PelD Cyclic Diguanylate Effector Involved in Pellicle Formation in Pseudomonas aeruginosa PAO1. J.Biol.Chem., 287, 2012
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4ETW
| Structure of the Enzyme-ACP Substrate Gatekeeper Complex Required for Biotin Synthesis | Descriptor: | Acyl carrier protein, Pimelyl-[acyl-carrier protein] methyl ester esterase, methyl 7-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxoheptanoate | Authors: | Agarwal, V, Nair, S.K. | Deposit date: | 2012-04-24 | Release date: | 2012-10-17 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proc.Natl.Acad.Sci.USA, 109, 2012
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5DLY
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5DM1
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5DZT
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5BKC
| Crystal structure of AAD-1 in complex with (R)-diclofop, Mn(II), and 2-oxoglutarate | Descriptor: | (2R)-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2019-06-02 | Release date: | 2019-06-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
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5BSM
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5BKB
| Crystal structure of AAD-1 in complex with (R)-dichlorprop, Mn(II), and 2-oxoglutarate | Descriptor: | (2R)-2-(2,4-dichlorophenoxy)propanoic acid, (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, ... | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2019-06-02 | Release date: | 2019-06-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.582 Å) | Cite: | Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
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