8FTV

SgvM methyltransferase triple variant (M144V/F329V/T331A) with SAH and 2-oxo-4-phenylbutanoic acid

Summary for 8FTV

• Entry DOI: 10.2210/pdb8ftv/pdb
• Related: 8FTR
• Descriptor: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (5 entities in total)
• Functional Keywords: methyltransferase, biosynthetic protein
• Biological source: Streptomyces griseoviridis
• Total number of polymer chains: 1
• Total formula weight: 37429.35

Authors

Kuzelka, K.,Nair, S.K. (deposition date: 2023-01-13, release date: 2023-11-01)

• Primary citation: Ju, S.,Kuzelka, K.P.,Guo, R.,Krohn-Hansen, B.,Wu, J.,Nair, S.K.,Yang, Y.; A biocatalytic platform for asymmetric alkylation of alpha-keto acids by mining and engineering of methyltransferases; Nat Commun, 14:5704-5704, 2023; PubMed: 37709735; DOI: 10.1038/s41467-023-40980-w

Experimental method

X-RAY DIFFRACTION (2.04 Å)