8FTV
SgvM methyltransferase triple variant (M144V/F329V/T331A) with SAH and 2-oxo-4-phenylbutanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyltransferase | polymer | 339 | 36801.3 | 1 | UniProt (R9UTR3) | Streptomyces griseoviridis | |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | 2-oxo-4-phenylbutanoic acid | non-polymer | 178.2 | 1 | Chemie (Y9E) PubChem (69732) | |||
| 5 | E (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 1 - 339 (UniProt: R9UTR3)
| PDB | External Database | Details |
|---|---|---|
| Val 144 | Met 144 | engineered mutation |
| Val 329 | Phe 329 | engineered mutation |
| Ala 331 | Thr 331 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36801.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 628.0 | |
| All* | Total formula weight | 37429.3 |
