8FTV
SgvM methyltransferase triple variant (M144V/F329V/T331A) with SAH and 2-oxo-4-phenylbutanoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyltransferase | polymer | 339 | 36801.3 | 1 | UniProt (R9UTR3) Pfam (PF08242) | Streptomyces griseoviridis | |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | 2-oxo-4-phenylbutanoic acid | non-polymer | 178.2 | 1 | Chemie (Y9E) | |||
| 5 | E (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 1 - 339 (UniProt: R9UTR3)
| PDB | External Database | Details |
|---|---|---|
| Val 144 | Met 144 | engineered mutation |
| Val 329 | Phe 329 | engineered mutation |
| Ala 331 | Thr 331 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36801.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 628.0 | |
| All* | Total formula weight | 37429.3 |
