Glutamylation domain, TbtB, from thiomuracin biosynthesis

Summary for 6EC7

DescriptorLantibiotic dehydratase domain protein (2 entities in total)
Functional Keywordsripp, thiopeptide, thiomuracin, trna-dependent, glutamylation, dehydratase, biosynthetic protein
Biological sourceThermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
Total number of polymer chains1
Total molecular weight96006.84
Cogan, D.P.,Nair, S.K. (deposition date: 2018-08-07, release date: 2019-08-14, Last modification date: 2019-09-25)
Primary citation
Bothwell, I.R.,Cogan, D.P.,Kim, T.,Reinhardt, C.J.,van der Donk, W.A.,Nair, S.K.
Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116:17245-17250, 2019
PubMed: 31409709 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1905240116
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2774 1.3% 4.5% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report