6APL
| Crystal Structure of human ST6GALNAC2 in complex with CMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, CYTIDINE-5'-MONOPHOSPHATE | 著者 | Forouhar, F, Moremen, K.W, Northeast Structural Genomics Consortium (NESG), Tong, L. | 登録日 | 2017-08-17 | 公開日 | 2017-12-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Expression system for structural and functional studies of human glycosylation enzymes. Nat. Chem. Biol., 14, 2018
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6APJ
| Crystal Structure of human ST6GALNAC2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 著者 | Forouhar, F, Moremen, K.W, Northeast Structural Genomics Consortium (NESG), Tong, L. | 登録日 | 2017-08-17 | 公開日 | 2017-12-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Expression system for structural and functional studies of human glycosylation enzymes. Nat. Chem. Biol., 14, 2018
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7MU8
| Structure of the minimally glycosylated human CEACAM1 N-terminal domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, ... | 著者 | Belcher Dufrisne, M, Swope, N, Kieber, M, Yang, J.Y, Han, J, Li, J, Moremen, K.W, Prestegard, J.H, Columbus, L. | 登録日 | 2021-05-14 | 公開日 | 2022-02-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human CEACAM1 N-domain dimerization is independent from glycan modifications. Structure, 30, 2022
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6XFI
| Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, ... | 著者 | Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N. | 登録日 | 2020-06-15 | 公開日 | 2021-04-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies. Acta Crystallogr D Struct Biol, 77, 2021
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6XI2
| Apo form of POMGNT2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-GLY-ALA-GLY-ALA-ALA-ALA-ALA-ALA-ALA, ... | 著者 | Halmo, S.M, Yeh, J, Wells, L, Moremen, K.W, Lanzilotta, W.N. | 登録日 | 2020-06-19 | 公開日 | 2021-04-21 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies. Acta Crystallogr D Struct Biol, 77, 2021
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1NXC
| Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases) | 分子名称: | CALCIUM ION, Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Tempel, W, Liu, Z.-J, Karaveg, K, Rose, J, Moremen, K.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2003-02-10 | 公開日 | 2004-05-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases J.Biol.Chem., 279, 2004
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1FMI
| CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE | 分子名称: | CALCIUM ION, ENDOPLASMIC RETICULUM ALPHA-MANNOSIDASE I, SULFATE ION | 著者 | Vallee, F, Karaveg, K, Herscovics, A, Moremen, K.W, Howell, P.L. | 登録日 | 2000-08-17 | 公開日 | 2001-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. J.Biol.Chem., 275, 2000
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1FO3
| CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH KIFUNENSINE | 分子名称: | ALPHA1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ... | 著者 | Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L. | 登録日 | 2000-08-24 | 公開日 | 2001-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. J.Biol.Chem., 275, 2000
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1FO2
| CRYSTAL STRUCTURE OF HUMAN CLASS I ALPHA1,2-MANNOSIDASE IN COMPLEX WITH 1-DEOXYMANNOJIRIMYCIN | 分子名称: | 1-DEOXYMANNOJIRIMYCIN, ALPHA1,2-MANNOSIDASE, CALCIUM ION, ... | 著者 | Vallee, F, Karaveg, K, Moremen, K.W, Herscovics, A, Howell, P.L. | 登録日 | 2000-08-24 | 公開日 | 2001-01-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. J.Biol.Chem., 275, 2000
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4MPS
| Crystal structure of rat Beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1), Northeast Structural Genomics Consortium Target RnR367A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactoside alpha-2,6-sialyltransferase 1 | 著者 | Forouhar, F, Meng, L, Milaninia, S, Seetharaman, J, Su, M, Kornhaber, G, Montelione, G.T, Hunt, J.F, Moremen, K.W, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-09-13 | 公開日 | 2013-09-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Enzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT alpha 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATION. J.Biol.Chem., 288, 2013
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1X9D
| Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue | 分子名称: | 1,4-BUTANEDIOL, CALCIUM ION, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ... | 著者 | Karaveg, K, Tempel, W, Liu, Z.J, Siriwardena, A, Moremen, K.W, Wang, B.C. | 登録日 | 2004-08-20 | 公開日 | 2005-02-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control. J.Biol.Chem., 280, 2005
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2WZS
| Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Mannoimidazole | 分子名称: | (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Zhu, Y, Suits, M.D.L, Thompson, A, Chavan, S, Dinev, Z, Dumon, C, Smith, N, Moremen, K.W, Xiang, Y, Siriwardena, A, Williams, S.J, Gilbert, H.J, Davies, G.J. | 登録日 | 2009-12-02 | 公開日 | 2009-12-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
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5FBH
| Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | 登録日 | 2015-12-14 | 公開日 | 2016-06-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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5FBK
| Crystal structure of the extracellular domain of human calcium sensing receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | 登録日 | 2015-12-14 | 公開日 | 2016-06-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Sci Adv, 2, 2016
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5KIJ
| Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase and Man9GlcNAc2-PA complex | 分子名称: | 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ... | 著者 | Karaveg, K, Xiang, Y, Moremen, K.W. | 登録日 | 2016-06-16 | 公開日 | 2017-05-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5KKB
| Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex | 分子名称: | 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | 著者 | Xiang, Y, Moremen, K.W. | 登録日 | 2016-06-21 | 公開日 | 2016-12-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.774 Å) | 主引用文献 | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5KK7
| Crystal structure of the class I human endoplasmic reticulum 1,2-alpha-mannosidase T688A mutant and Thio-disaccharide substrate analog complex | 分子名称: | 1,4-BUTANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ACETATE ION, ... | 著者 | Karaveg, K, Xiang, Y, Moremen, K.W. | 登録日 | 2016-06-21 | 公開日 | 2017-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7324 Å) | 主引用文献 | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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7SCJ
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7SCH
| Cryo-EM structure of the human Exostosin-1 and Exostosin-2 heterodimer | 分子名称: | Exostosin-1, Exostosin-2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Li, H, Li, H. | 登録日 | 2021-09-28 | 公開日 | 2022-09-28 | 最終更新日 | 2023-05-17 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex. Nat.Chem.Biol., 19, 2023
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7SCK
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7UQY
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7UQX
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6CCI
| The Crystal Structure of XOAT1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Alahuhta, P.M, Lunin, V.V. | 登録日 | 2018-02-07 | 公開日 | 2019-02-20 | 最終更新日 | 2020-09-02 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis XylanO-acetyltransferase XOAT1. Plant Cell, 32, 2020
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2WW3
| Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with thiomannobioside | 分子名称: | CALCIUM ION, GLYCEROL, PUTATIVE ALPHA-1,2-MANNOSIDASE, ... | 著者 | Suits, M.D.L, Zhu, Y, Thompson, A.J, Gilbert, H.J, Davies, G.J. | 登録日 | 2009-10-21 | 公開日 | 2010-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanistic Insights Into a Ca(2+)-Dependent Family of Alpha-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
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2WW1
| Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482 in complex with Thiomannobioside | 分子名称: | PUTATIVE ALPHA-1,2-MANNOSIDASE, alpha-D-mannopyranose-(1-2)-methyl 2-thio-alpha-D-mannopyranoside | 著者 | Suits, M.D.L, Zhu, Y, Thompson, A, Gilbert, H.J, Davies, G.J. | 登録日 | 2009-10-21 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont. Nat.Chem.Biol., 6, 2010
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