9B8Z
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9B93
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9B8Y
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9B92
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8SR8
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8SRB
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8SRC
| Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SR7
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (1.97 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SR9
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8SRA
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8SRD
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRI
| Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRG
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRK
| Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRH
| Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRJ
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8SRF
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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8SRE
| Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution To Be Published
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4TLL
| Crystal structure of GluN1/GluN2B NMDA receptor, structure 1 | Descriptor: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | Authors: | Gouaux, E, Lee, C.-H, Lu, W. | Deposit date: | 2014-05-30 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.59 Å) | Cite: | NMDA receptor structures reveal subunit arrangement and pore architecture. Nature, 511, 2014
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4RSY
| Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7 | Descriptor: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, ACETIC ACID, IMIDAZOLE, ... | Authors: | Ouyang, P, Lu, W, Cui, K, Huang, J. | Deposit date: | 2014-11-12 | Release date: | 2015-12-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1 To be Published
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4RVB
| Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase | Descriptor: | ACETATE ION, ACETIC ACID, GLYCEROL, ... | Authors: | Ouyang, P, Lu, W, Cui, K, Huang, J. | Deposit date: | 2014-11-25 | Release date: | 2015-12-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase To be Published
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4TLM
| Crystal structure of GluN1/GluN2B NMDA receptor, structure 2 | Descriptor: | 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ... | Authors: | Gouaux, E, Lee, C.-H, Lu, W. | Deposit date: | 2014-05-30 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.77 Å) | Cite: | NMDA receptor structures reveal subunit arrangement and pore architecture. Nature, 511, 2014
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2PM5
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2PM1
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2PM4
| Human alpha-defensin 1 (multiple Arg->Lys mutant) | Descriptor: | Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) | Authors: | Lubkowski, J, Pazgier, M, Lu, W. | Deposit date: | 2007-04-20 | Release date: | 2007-05-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J.Biol.Chem., 282, 2007
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