6L7O
| cryo-EM structure of cyanobacteria Fd-NDH-1L complex | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | 著者 | Zhang, C, Shuai, J, Wu, J, Lei, M. | 登録日 | 2019-11-02 | 公開日 | 2020-02-19 | 最終更新日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into NDH-1 mediated cyclic electron transfer. Nat Commun, 11, 2020
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6LBS
| Crystal structure of yeast Stn1 | 分子名称: | KLLA0C11825p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBR
| Crystal structure of yeast Cdc13 and ssDNA | 分子名称: | KLLA0F20922p, Telomere single-strand DNA | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBU
| Crystal structure of yeast Stn1 and Ten1 | 分子名称: | KLLA0C11825p, KLLA0E09417p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6LBT
| Crystal structure of yeast Cdc13 and Stn1 | 分子名称: | GLYCEROL, KLLA0C11825p, KLLA0F20922p,KLLA0F20922p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6L7P
| cryo-EM structure of cyanobacteria NDH-1LdelV complex | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | 著者 | Zhang, C, Shuai, J, Wu, J, Lei, M. | 登録日 | 2019-11-02 | 公開日 | 2020-02-19 | 最終更新日 | 2021-09-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into NDH-1 mediated cyclic electron transfer. Nat Commun, 11, 2020
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6MLC
| PHD6 domain of MLL3 in complex with histone H4 | 分子名称: | GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ... | 著者 | Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-09-27 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun, 10, 2019
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5WQD
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5XUP
| Crystal structure of TRF1 and TERB1 | 分子名称: | Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1 | 著者 | Long, J, Huang, C, Wu, J, Lei, M. | 登録日 | 2017-06-24 | 公開日 | 2017-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Telomeric TERB1-TRF1 interaction is crucial for male meiosis. Nat. Struct. Mol. Biol., 24, 2017
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5Y59
| Crystal structure of Ku80 and Sir4 | 分子名称: | ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | 登録日 | 2017-08-08 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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5Y5A
| Crystal structure of Est1 and Cdc13 | 分子名称: | KLLA0F20702p, KLLA0F20922p | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | 登録日 | 2017-08-08 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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5Y58
| Crystal structure of Ku70/80 and TLC1 | 分子名称: | ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1 | 著者 | Chen, H, Xue, J, Wu, J, Lei, M. | 登録日 | 2017-08-08 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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7WTE
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | 分子名称: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTB
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTA
| Cryo-EM structure of human pyruvate carboxylase in apo state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTD
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTC
| Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, Pyruvate carboxylase, ... | 著者 | Chai, P, Lan, P, Wu, J, Lei, M. | 登録日 | 2022-02-04 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7V2Y
| cryo-EM structure of yeast THO complex with Sub2 | 分子名称: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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7V2W
| protomer structure from the dimer of yeast THO complex | 分子名称: | Protein TEX1, THO complex subunit 2, THO complex subunit HPR1, ... | 著者 | Chen, C, Tan, M, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-10 | 公開日 | 2022-07-27 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex. Sci Bull (Beijing), 66, 2021
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7X5C
| Solution structure of Tetrahymena p75OB1-p50PBM | 分子名称: | Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1 | 著者 | Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M. | 登録日 | 2022-03-04 | 公開日 | 2022-10-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance Structure, 2022
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7X9G
| Crystal structure of human EDA and EDAR | 分子名称: | Ectodysplasin-A, secreted form, Tumor necrosis factor receptor superfamily member EDAR | 著者 | Yu, K, Wan, F, Huang, C, Wu, J, Lei, M. | 登録日 | 2022-03-15 | 公開日 | 2023-02-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants. Nat Commun, 14, 2023
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7V9A
| biogenesis module of human telomerase holoenzyme | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-24 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | 主引用文献 | Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
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7V99
| catalytic core of human telomerase holoenzyme | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... | 著者 | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | 登録日 | 2021-08-24 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
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6BPH
| Crystal structure of the chromodomain of RBBP1 | 分子名称: | AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-11-23 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of chromo barrel domain of RBBP1. Biochem. Biophys. Res. Commun., 496, 2018
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6C1Y
| mbd of human mecp2 in complex with methylated DNA | 分子名称: | 12-mer DNA, Methyl-CpG-binding protein 2, UNKNOWN ATOM OR ION | 著者 | Liu, K, Bian, C, Tempel, W, Wernimont, A.K, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-01-05 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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