6C1Y
mbd of human mecp2 in complex with methylated DNA
Summary for 6C1Y
Entry DOI | 10.2210/pdb6c1y/pdb |
Descriptor | Methyl-CpG-binding protein 2, 12-mer DNA, UNKNOWN ATOM OR ION (3 entities in total) |
Functional Keywords | mbd, dna methylation, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 34283.68 |
Authors | Liu, K.,Bian, C.,Tempel, W.,Wernimont, A.K.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-01-05, release date: 2018-02-14, Last modification date: 2023-10-04) |
Primary citation | Lei, M.,Tempel, W.,Chen, S.,Liu, K.,Min, J. Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862:194409-194409, 2019 Cited by PubMed: 31356990DOI: 10.1016/j.bbagrm.2019.194409 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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