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7XBD
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BU of 7xbd by Molmil
Cryo-EM structure of human galanin receptor 2
Descriptor: Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ishimoto, N, Kita, S, Park, S.Y.
Deposit date:2022-03-21
Release date:2022-07-13
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.
Plos Biol., 20, 2022
3TGM
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BU of 3tgm by Molmil
X-Ray Crystal Structure of Human Heme Oxygenase-1 in Complex with 1-(1H-imidazol-1-yl)-4,4-diphenyl-2 butanone
Descriptor: 1-(1H-imidazol-1-yl)-4,4-diphenylbutan-2-one, HEXANE-1,6-DIOL, Heme oxygenase 1, ...
Authors:Rahman, M.N, Jia, Z.
Deposit date:2011-08-17
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A novel, "double-clamp" binding mode for human heme oxygenase-1 inhibition.
Plos One, 7, 2012
1CO0
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BU of 1co0 by Molmil
NMR STUDY OF TRP REPRESSOR-MTR OPERATOR DNA COMPLEX
Descriptor: 5'-D(*TP*GP*TP*AP*CP*CP*AP*GP*TP*AP*CP*AP*CP*GP*AP*GP*TP*AP*CP*A)-3', 5'-D(*TP*GP*TP*AP*CP*TP*CP*GP*TP*GP*TP*AP*CP*TP*GP*GP*TP*AP*CP*A)-3', TRP OPERON REPRESSOR, ...
Authors:Zhou, G.P, Brocchieri, L, Jardetzky, O.
Deposit date:1999-05-30
Release date:2003-09-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Allostery and Induced Fit, NMR and Molecular Modeling Study of the trp-repressor - mtr DNA complex
Structures and Mechanisms, ACS Symposium Series, 827, 2002
6JCG
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BU of 6jcg by Molmil
Room temperature structure of HIV-1 Integrase catalytic core domain by serial femtosecond crystallography.
Descriptor: CACODYLATE ION, Integrase
Authors:Park, J.H, Shi, Y, Han, J, Li, X, Kim, T.H, Yun, J.H.
Deposit date:2019-01-28
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
6LH8
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BU of 6lh8 by Molmil
Structure of aerolysin-like protein (Bombina maxima)
Descriptor: aerolysin-like protein
Authors:Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
Deposit date:2019-12-07
Release date:2020-06-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
6LHZ
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BU of 6lhz by Molmil
Structure of aerolysin-like protein (Bombina maxima)
Descriptor: aerolysin-like protein
Authors:Bian, X.L, Wang, Q.Q, Li, X, Teng, M.Q, Zhang, Y.
Deposit date:2019-12-10
Release date:2020-06-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions.
J.Biol.Chem., 295, 2020
1IKI
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BU of 1iki by Molmil
COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH THE PRODUCTS OF A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT
Descriptor: D-ALANINE, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANINE
Authors:Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A.
Deposit date:2001-05-03
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
1IKG
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BU of 1ikg by Molmil
MICHAELIS COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT
Descriptor: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANYL-D-ALANINE
Authors:Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A.
Deposit date:2001-05-03
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
1PWD
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BU of 1pwd by Molmil
Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C
Descriptor: (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase precursor
Authors:Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PW1
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BU of 1pw1 by Molmil
Non-Covalent Complex Of Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin
Descriptor: (2S,5R,6R)-6-{[(6R)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, D-alanyl-D-alanine carboxypeptidase, FORMYL GROUP, ...
Authors:Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A.
Deposit date:2003-06-30
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWC
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BU of 1pwc by Molmil
penicilloyl acyl enzyme complex of the Streptomyces R61 DD-peptidase with penicillin G
Descriptor: D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G
Authors:Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PW8
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BU of 1pw8 by Molmil
Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin
Descriptor: (6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE, D-alanyl-D-alanine carboxypeptidase, GLYCEROL
Authors:Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWG
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BU of 1pwg by Molmil
Covalent Penicilloyl Acyl Enzyme Complex Of The Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin
Descriptor: (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase
Authors:Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.074 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1WRS
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BU of 1wrs by Molmil
NMR STUDY OF HOLO TRP REPRESSOR
Descriptor: HOLO TRP REPRESSOR, TRYPTOPHAN
Authors:Zhao, D, Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
1WRT
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BU of 1wrt by Molmil
NMR STUDY OF APO TRP REPRESSOR
Descriptor: APO TRP REPRESSOR
Authors:Zhao, D, Zheng, Z.
Deposit date:1995-05-12
Release date:1996-06-20
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Refined solution structures of the Escherichia coli trp holo- and aporepressor.
J.Mol.Biol., 229, 1993
2PE2
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BU of 2pe2 by Molmil
CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 3-{5-[2-Oxo-5-ureido-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrol-3-yl}-N-(2-piperidin-1-yl-ethyl)-benzamide COMPLEX
Descriptor: 3-[5-({5-[(AMINOCARBONYL)AMINO]-2-OXO-2H-INDOL-3-YL}METHYL)-1H-PYRROL-3-YL]-N-(2-PIPERIDIN-1-YLETHYL)BENZAMIDE, 3-phosphoinositide-dependent protein kinase 1, GLYCEROL, ...
Authors:Whitlow, M, Adler, M.
Deposit date:2007-04-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX-517.
Bioorg.Med.Chem.Lett., 17, 2007

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