1PWC

penicilloyl acyl enzyme complex of the Streptomyces R61 DD-peptidase with penicillin G

Summary for 1PWC

Entry DOI	10.2210/pdb1pwc/pdb
Related	1IKG 1IKI 1MPL
Descriptor	D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G (3 entities in total)
Functional Keywords	beta-lactam, antibiotics, penicillin binding protein, enzyme, peptidoglycan, hydrolase
Biological source	Streptomyces sp.
Cellular location	Secreted: P15555
Total number of polymer chains	1
Total formula weight	37758.98
Authors	Silvaggi, N.R.,Josephine, H.R.,Pratt, R.F.,Kelly, J.A. (deposition date: 2003-07-01, release date: 2004-07-13, Last modification date: 2023-08-16)
Primary citation	Silvaggi, N.R.,Josephine, H.R.,Kuzin, A.P.,Nagarajan, R.,Pratt, R.F.,Kelly, J.A. Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345:521-533, 2005 Cited by PubMed: 15581896 DOI: 10.1016/j.jmb.2004.10.076 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation