1MPL
CRYSTAL STRUCTURE OF PHOSPHONATE-INHIBITED D-ALA-D-ALA PEPTIDASE REVEALS AN ANALOG OF A TETRAHEDRAL TRANSITION STATE
Summary for 1MPL
Entry DOI | 10.2210/pdb1mpl/pdb |
Related | 1IKG 1IKI |
Descriptor | D-alanyl-D-alanine carboxypeptidase, GLYCYL-L-A-AMINOPIMELYL-E-(D-2-AMINOETHYL)PHOSPHONATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transition state analog, peptidoglycan, penicillin binding protein, hydrolase |
Biological source | Streptomyces sp. |
Total number of polymer chains | 1 |
Total formula weight | 38221.32 |
Authors | Silvaggi, N.R.,Anderson, J.W.,Brinsmade, S.R.,Pratt, R.F.,Kelly, J.A. (deposition date: 2002-09-12, release date: 2003-02-25, Last modification date: 2019-07-24) |
Primary citation | Silvaggi, N.R.,Anderson, J.W.,Brinsmade, S.R.,Pratt, R.F.,Kelly, J.A. The Crystal Structure of Phosphonate-Inhibited d-Ala-d-Ala Peptidase Reveals an Analogue of a Tetrahedral Transition State. Biochemistry, 42:1199-1208, 2003 Cited by PubMed: 12564922DOI: 10.1021/bi0268955 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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