1PW8
Covalent Acyl Enzyme Complex Of The R61 DD-Peptidase with A Highly Specific Cephalosporin
Summary for 1PW8
Entry DOI | 10.2210/pdb1pw8/pdb |
Related | 1IKG 1IKI 1MPL |
Descriptor | D-alanyl-D-alanine carboxypeptidase, (6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | beta-lactam, antibiotics, penicillin binding protein, enzyme, peptidoglycan, hydrolase |
Biological source | Streptomyces sp. |
Total number of polymer chains | 1 |
Total formula weight | 38094.27 |
Authors | Silvaggi, N.R.,Josephine, H.R.,Pratt, R.F.,Kelly, J.A. (deposition date: 2003-07-01, release date: 2004-07-13, Last modification date: 2023-08-16) |
Primary citation | Silvaggi, N.R.,Josephine, H.R.,Kuzin, A.P.,Nagarajan, R.,Pratt, R.F.,Kelly, J.A. Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345:521-533, 2005 Cited by PubMed: 15581896DOI: 10.1016/j.jmb.2004.10.076 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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