3KO1
| Cystal structure of thermosome from Acidianus tengchongensis strain S5 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin | 著者 | Huo, Y, Zhang, K, Hu, Z, Wang, L, Zhai, Y, Zhou, Q, Lander, G, He, Y, Zhu, J, Xu, W, Dong, Z, Sun, F. | 登録日 | 2009-11-12 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Crystal structure of group II chaperonin in the open state. Structure, 18, 2010
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2FS3
| Bacteriophage HK97 K169Y Head I | 分子名称: | Major capsid protein | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | 登録日 | 2006-01-20 | 公開日 | 2006-02-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM. Structure, 14, 2006
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2FTE
| Bacteriophage HK97 Expansion Intermediate IV | 分子名称: | major capsid protein | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | 登録日 | 2006-01-24 | 公開日 | 2006-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM. Structure, 14, 2006
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2FRP
| Bacteriophage HK97 Expansion Intermediate IV | 分子名称: | Major capsid protein | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | 登録日 | 2006-01-19 | 公開日 | 2006-02-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (7.5 Å) | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM. Structure, 14, 2006
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2FT1
| Bacteriophage HK97 Head II | 分子名称: | major capsid protein | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | 登録日 | 2006-01-23 | 公開日 | 2006-02-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM. Structure, 14, 2006
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2FSY
| Bacteriophage HK97 Pepsin-treated Expansion Intermediate IV | 分子名称: | major capsid protein | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | 登録日 | 2006-01-23 | 公開日 | 2006-02-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM. Structure, 14, 2006
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8QVI
| Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | 分子名称: | Bifunctional epoxide hydrolase 2, DI(HYDROXYETHYL)ETHER | 著者 | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | 登録日 | 2023-10-18 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Exploring serial crystallography for drug discovery To Be Published
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6WHI
| Cryo-electron microscopy structure of the type I-F CRISPR RNA-guided surveillance complex bound to the anti-CRISPR AcrIF9 | 分子名称: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ... | 著者 | Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G. | 登録日 | 2020-04-08 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Nat Commun, 11, 2020
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8FFY
| Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(UGA-TL) | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial, ... | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | 登録日 | 2022-12-11 | 公開日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition. Nat Commun, 14, 2023
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7U2B
| Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA(GCU-TL) | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (53-MER), Serine--tRNA ligase, ... | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | 登録日 | 2022-02-23 | 公開日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA. Nat Commun, 13, 2022
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7U2A
| Cryo-electron microscopy structure of human mt-SerRS in complex with mt-tRNA (GCU) | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, RNA (38-MER), Serine--tRNA ligase, ... | 著者 | Hirschi, M, Kuhle, B, Doerfel, L, Schimmel, P, Lander, G. | 登録日 | 2022-02-23 | 公開日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA. Nat Commun, 13, 2022
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7TZB
| Crystal structure of the human mitochondrial seryl-tRNA synthetase (mt SerRS) bound with a seryl-adenylate analogue | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, Serine--tRNA ligase, mitochondrial | 著者 | Kuhle, B, Hirschi, M, Doerfel, L, Lander, G, Schimmel, P. | 登録日 | 2022-02-15 | 公開日 | 2022-09-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA. Nat Commun, 13, 2022
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6W1X
| Cryo-EM structure of anti-CRISPR AcrIF9, bound to the type I-F crRNA-guided CRISPR surveillance complex | 分子名称: | CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ... | 著者 | Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G. | 登録日 | 2020-03-04 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex. Nat Commun, 11, 2020
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4U67
| Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 | 分子名称: | 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | 登録日 | 2014-07-28 | 公開日 | 2015-08-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure, 25, 2017
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6GSP
| RIBONUCLEASE T1/3'-GMP, 15 WEEKS | 分子名称: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-09 | 公開日 | 1998-03-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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4WFN
| Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A. | 登録日 | 2014-09-16 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.54 Å) | 主引用文献 | The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. Structure, 25, 2017
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4GSP
| RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS | 分子名称: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ... | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-02 | 公開日 | 1998-08-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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3GSP
| RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 4 DAYS | 分子名称: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ... | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-02 | 公開日 | 1998-08-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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1GSP
| RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY | 分子名称: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, RIBONUCLEASE T1 | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-11-28 | 公開日 | 1998-02-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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5GSP
| RIBONUCLEASE T1/3'-GMP, 9 WEEKS | 分子名称: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-09 | 公開日 | 1998-03-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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2GSP
| RIBONUCLEASE T1/2',3'-CGPS AND 3'-GMP, 2 DAYS | 分子名称: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ... | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-02 | 公開日 | 1998-08-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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7GSP
| RIBONUCLEASE T1/2',3'-CGPS, NON-PRODUCTIVE | 分子名称: | GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, PHOSPHATE ION, RIBONUCLEASE T1 | 著者 | Zegers, I, Wyns, L. | 登録日 | 1997-12-10 | 公開日 | 1998-03-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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8QK5
| Structure of K. pneumoniae LpxH in complex with EBL-3647 | 分子名称: | 5-[[3-(aminomethyl)azetidin-1-yl]methyl]-N-[4-[4-(4-cyano-6-methyl-pyrimidin-2-yl)piperazin-1-yl]sulfonylphenyl]-2-[methyl(methylsulfonyl)amino]benzamide, MANGANESE (II) ION, UDP-2,3-diacylglucosamine hydrolase | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2023-09-14 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria. Proc.Natl.Acad.Sci.USA, 121, 2024
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8QK2
| Structure of K.pneumoniae LpxH in complex with EBL-3339 | 分子名称: | MANGANESE (II) ION, UDP-2,3-diacylglucosamine hydrolase, ~{N}-[4-[4-(4-cyano-6-methyl-pyrimidin-2-yl)piperazin-1-yl]sulfonylphenyl]-2-[methyl(methylsulfonyl)amino]benzamide | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2023-09-14 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria. Proc.Natl.Acad.Sci.USA, 121, 2024
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8QJZ
| Crystal structure of E. coli LpxH in complex with lipid X | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, MANGANESE (II) ION, UDP-2,3-diacylglucosamine hydrolase | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2023-09-14 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria. Proc.Natl.Acad.Sci.USA, 121, 2024
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